GDC-0994

• Product NameGDC-0994
  CAS No.1453848-26-4
  Purity>98%
  Min Quantity
  Price~
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Detailed Description

GDC-0994GDC-0994 is highly selective for ERK1 and ERK2, with biochemical potency of 1.1 nM and 0.3 nM, respectively.

IC50 value: 1.1 nM/0.3 nM(ERK1/ERK2) [1]

Target: ERK1/ERK2 inhibitor

Daily, oral dosing of GDC-0994 results in significant single-agent activity in multiple in vivo cancer models, including KRAS-mutant and BRAF-mutant human xenograft tumors in mice.

Target:HIF

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