Orlistat

• Product NameOrlistat
  CAS No.96829-58-2
  Purity99%
  Min Quantity1000Kilograms
  Price1~2
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  Molecular Structure

Detailed Description

Orlistat
Synonyms:(s)-2-formylamino-4-methyl-pentanoic acid (s)-1-[[(2s,3s)-3-hexyl-4-oxo-2-oxetanyl]methyl]-dodecyl ester;Ro-18-0647;(-)-tetrahydrolipstatin(equivalenttoorlistat);Orlipastat
CAS: 96829-58-2
MF: C29H53NO5
MW: 495.73
Product CategoriesN/A: Pharmaceutical Raw Materials;Miscellaneous Biochemicals;Antiobesity Agent;Chiral Reagents;Pharmaceuticals
Chemical Properties Off-White Solid
Usage An antiobesity agent. A pancreatic lipase inhibitor. Antiobesity agent. Tetrahydrolipstatin (orlistat) is a semi-synthetic derivative of lipstatin, a metabolite isolated from Streptomyces toxytricini. Tetrahydrolipstatin acts as a potent, irreversible inhibitor of pancreatic lipase. In vivo, it blocks the absorption of triglycerides while allowing fatty acid absorption. Tetrahydrolipstatin is widely used for the treatment of obesity.
Packing:1kg/foil bag or as required
TESTS Specificatione Results
Description White or almost crystalline powder White crystalline powder
Identification IR Conforms
Specific rotation -33 -35° -34°
Loss on drying <0.5% 0.35%
Melting point 42-45℃ 42-44℃
Water <=2.0% 0.25%
Residual solvents n-hexane<=290ppm n-heptane<=5000ppm 20ppm 1260ppm
Assay(HPLC) >=96.0%(ON DRY BASIS) 97.4%
This medication is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who are obese or have weight-related medical problems. Taking orlistat can also help keep you from gaining back weight you have lost. Losing weight and keeping it off can lessen the many health risks that come with obesity, including heart disease, diabetes, high blood pressure, and a shorter life.

Dietary fats need to be broken down into smaller pieces before the body can absorb them. Orlistat works by blocking the enzyme that breaks down fats in your diet. This undigested fat then passes out of your body in your bowel movement. Orlistat does not block the absorption of calories from sugar and other non-fat foods, so you still need to restrict your total intake of calories.
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• Orlistat