Estradiol benzoate Estradiol benzoate Estradiol benzoate Estradiol benzoate

• Product NameEstradiol benzoate Estradiol benzoate Estradiol benzoate Estradiol benzoate
  CAS No.50-50-0
  Purity99%
  Min Quantity200Kilograms
  Price800~1600
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  Molecular Structure

Detailed Description

Estradiol benzoate Estradiol benzoate Estradiol benzoate Estradiol benzoate
Synonyms: (17beta)-Estra-1,3,5(10)-triene-3,17-diol 3-benzoate;1,3,5(10)-Estratriene-3,17-diol-3-benzoate;1,3,5(10)-Oestratriene-3,17-beta-diol 3-benzoate;1,3,5(10)-oestratriene-3,17-beta-diol3-benzoate;17beta-Estradiol monobenzoate;17-beta-estradiolmonobenzoate;17-beta-Oestradiol 3-benzoate;17-beta-oestradiol3-benzoate
CAS: 50-50-0
MF: C25H28O3
MW: 376.49
EINECS: 200-043-7
Chemical Properties White solid
Usage antiacne, antineoplastic
Usage Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an
estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the
treatment of lesions produced by diminution of bodily production of estrogens.


Estradiol benzoate (INN; brand names Agofollin, Diffolisterol, Progynon-B, many others), or oestradiol benzoate (BAN), is a synthetic ester, specifically the 3-benzoyl ester, of the natural estrogen, estradiol.[1][2] It was the first form of estrogen to be marketed, patented by Schering-Kahlbaum in 1936 in an oil preparation for injectable use and introduced later that year as Progynon-B.[3][4] Though it is still in widespread use today, it has been mostly superseded by newer forms of estradiol with improved pharmacokinetics that require less frequent administration such as estradiol cypionate and estradiol valerate.[5]

A single dose of 2.5 mg estradiol benzoate by intramuscular injection was found to produce plasma estradiol levels of >400 pg/mL, measured 24 hours post-injection, in a group of patients with minimal baseline levels of estradiol (due to GnRH analogue therapy with triptorelin).[6]



Uses
Consult your pharmacist.

How to use estradiol benzoate (bulk)
Consult your pharmacist.
Side Effects
Consult your pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Precautions
Consult your pharmacist.
Interactions
Consult your pharmacist.

Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Estradiol valerate Pronunciation
Generic Name: estradiol valerate (ess-tra-DIE-ole)
Brand Name: Delestrogen

Estrogens have been reported to increase the chance of womb (endometrial) cancer in women who have been through menopause, especially in women who receive estrogen-only hormone therapy. Contact your doctor immediately if you experience any unusual vaginal bleeding. Estrogens may also increase the risk of cancer of the ovary or breast. Estrogen-containing products should not be used to prevent heart disease. Estrogen given with another hormone (progestin) for replacement therapy can infrequently cause heart disease (eg, heart attacks), stroke, serious blood clots in the legs or lungs (pulmonary embolism/deep vein thrombosis), dementia, and cancer of the breast. These risks appear to depend on the length of time estradiol valerate is used and the amount of estrogen per dose. Therefore, estradiol valerate should be used for the shortest possible length of time at the lowest effective dose so that you obtain the benefits and minimize the chance of serious side effects from long-term treatment. Consult your doctor or pharmacist for details.


Estradiol valerate is used for:

Treating certain symptoms of menopause (eg, hot flashes, vaginal itching, burning, or dryness). It is used to treat low levels of estrogen caused by certain conditions. It may be used to treat certain types of prostate cancer (advanced androgen-dependent). It may also be used for other conditions as determined by your doctor.

Estradiol valerate is a female estrogen hormone. It works by replacing natural estrogens in a woman who can no longer produce enough estrogen.It works for advanced prostate cancer by antagonizing male hormones.

Do NOT use estradiol valerate if:
you are allergic to any ingredient in estradiol valerate
you are pregnant or suspect you may be pregnant, or you have vaginal bleeding of abnormal or unknown cause
you have a history of known or suspected breast cancer (unless your doctor tells you otherwise)
you have any other estrogen-dependent cancer
you have the blood disease porphyria, or a history of blood clots or liver problems
you have had a recent (within the past year) stroke or heart attack
Contact your doctor or health care provider right away if any of these apply to you.


Do NOT use estradiol valerate if:
you are allergic to any ingredient in estradiol valerate
you are pregnant or suspect you may be pregnant, or you have vaginal bleeding of abnormal or unknown cause
you have a history of known or suspected breast cancer (unless your doctor tells you otherwise)
you have any other estrogen-dependent cancer
you have the blood disease porphyria, or a history of blood clots or liver problems
you have had a recent (within the past year) stroke or heart attack
Contact your doctor or health care provider right away if any of these apply to you.
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