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Epothilone B

  • CAS No:152044-54-7 (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,<br />16-pentamethyl-3-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-4,<br />17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
    Molecular Structure

    Detailed Description

    Epothilone B
    Synonym: EPO906, EpoB, Patupilone, Molecular Formula:C27H41NO6S
    Molecular Weight: 507.68
    CAS Number:
    AppearanceColorless crystals
    Purity (HPLC):99.0%
    Descriptions:
    A compound isolated from the myxobacterium Sorangium cellulosum. Similar to paclitaxel, epothilone B induces microtubule polymerization and stabilizes microtubules against depolymerization conditions. In addition to promoting tubulin polymerization and stabilization of microtubules, this agent is cytotoxic for cells overexpressing P-glycoprotein, a characteristic that distinguishes it from the taxanes. Epothilone B may cause complete cell-cycle arrest.
    Packing: Preserved in tight container 50g /bottle or in demand
    storage condition desiccated
    protect from light,storage temp.: 20
  • Epothilone B
  • Epothilone B