Ethisterone
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Molecular Structure
Detailed Description
Ethisterone
Product Name:Ethisterone
CAS: 434-03-7
MF: C21H28O2
MW: 312.45
EINECS: 207-096-5
mp 263-269 °C(lit.)
storage temp. -20°C Freezer
Packaging: 1kg/tin
Chemical Properties: White or kind of white crystalline powder
Usage: Synthetic progestogen; metabolite of Danazol; intermediate in the synthesis of Spironolactone
Description:
Ethisterone (pregneninolone, 17α-ethynyltestosterone or 19-norandrostane) is a progestin. It is the 17α-ethynyl analog of testosterone, and was synthesized in 1938 by Hans Herloff Inhoffen, Willy Logemann, Walter Hohlweg, and Arthur Serini at Schering AG in Berlin and marketed in Germany in 1939 as Proluton C and by Schering in the U.S. in 1945 as Pranone. It was the first orally-active progestin.
Application:
In recent years, estrogen replacement therapy has been criticized for its association with breast and uterine cancer, heart disease, and strokes. Hormone replacement therapy (HRT) should be used only in extreme cases and always under the supervision of a healthcare professional.
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