Paclitaxel Injection

• Product NamePaclitaxel Injection
  CAS No.33069-62-4
  Purity99.999%
  Min Quantity30FCL
  Price~
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  Molecular Structure

Detailed Description

Chemical Name: Paclitaxel
CAS Number: 33069-62-4
Molecular Formula: C15H24N202
Molecular Weight: 264.36
Purity: 99%
Appearance: white crystalline powder
Applications/Function:Paclitaxel isAmitotic inhibitor used in cancer chemotherapy. It was discovered inANational Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree, Taxus brevifoli Aand named it 'taxol'. When it was developed commercially by Bristol-Myers Squibb (BMS) the generic name was changed to 'paclitaxel' and the BMS compound is sold under the trademark 'TAXOL'. In this formulation, paclitaxel is dissolved in Cremophor EL and ethanol, asAdelivery agent.Anewer formulation, in which paclitaxel is bound to albumin, is sold under the trademark Abraxane.
Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is also used for the prevention of restenosis.
Paclitaxel stabilizes microtubules and asAresult, interferes with the normal breakdown of microtubules during cell division. Together with docetaxel, it forms the drug category of the taxanes.
These are available in 30mg compositions.