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Ibuprofen

  • CAS No:15687-27-1 2-[4-(2-methylpropyl)phenyl]propanoic acid
    Molecular Structure

    Detailed Description

    Specifications

    Ibuprofen 15687-27-1
    CAS:15687-27-1
    assay:>99%
    appearance:white powder

    Ibuprofen 15687-27-1
    CAS:15687-27-1
    assay:>99%
    appearance:white powder

    Test items
    Specifications
    Results
    Apperance
    White crystalline powder
    Conforms
    Solubility
    Practically insoluble in water,very soluble in alcohol,in methanol ,in acetone,and in chloroform;slightly soluble in ethyl acetate.
    Conforms
    Identification
    IR
    UV
    HPLC
    sample IR spectrum corresponds to that of the standard
    sample UC spectrum does not differ form that of the standard by more than 3.0%
    retention time corresponds to that of the standard

    Conforms

    Conforms

    Conforms
    Residual on ignition
    Not more than 0.5%
    0.01%
    Chromatographic purity
    2-[3-(2methylpropyl)phenyl]propanoic acid:not more than 0.15%
    2-(4-methylphenyl)propanoic acid:not more than 0.15%
    2-(4-ethylphenyl)propanoic acid:not more than 0.15%
    2-(4-propylphenyl)propanoic acid:not more than 0.15%
    2-(4-butylphenyl)propanoic acid:not more than 0.1%
    Any unknown impurity:not more than 0.05%
    Total impurities:not more than 0.6%
    0.06%

    Not detected
    0.02%
    0.01%
    Not detected
    0.02%
    0.12%
    4-isobutylacetophenone
    Not more than 0.1%
    Not detected
    Water content
    Not more that 1.0%
    0.12%
    Heavy Metals
    Not more than 0.002%
    <0.002%
    Residual solvents(petroleum ether)
    Not more than 250ppm
    55ppm
    Assay(dry basis)
    97.0-103.0%
    99.50%
    Bulk density
    0.20-0.50g/ml
    0.29g/ml
    Tapped density
    0.40-0.70g/ml
    0.50g/ml
    Median particle size
    30-60um
    37.9um
    Conclusion
    Comply with USP32
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