Zhuzhou Hezhong Technology Development C

Zhuzhou Hezhong Technology Development C

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GW501516

  • CAS No:317318-70-0 2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,<br />3-thiazol-5-yl]methylsulfanyl]phenoxy]acetic acid
    Molecular Structure

    Detailed Description

    GW501516

    Alias: 2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid;
    GW1516;
    GW501516;
    GSK-516

    CAS: 317318-70-0
    M.F.: C21H18F3NO3S2
    M.W.: 453.5
    M.S.:

    M.P.: 134-136°C

    Chemical Properties :White Solid.

    Usage:An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARd agonist. Exhibits selectivity for PPARd compared.

    An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist. Exhibits selectivity for PPARδ compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells.
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  • GW501516
  • GW501516