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1-(6-Aminopurin-9-yl)propan-2-yloxymethylphosphonic acid /Tenofovir

  • Product Name1-(6-Aminopurin-9-yl)propan-2-yloxymethylphosphonic acid /Tenofovir
    CAS No.147127-20-6
    Purity98%min
    Min Quantity500Kilograms
    Price500~1500
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  • CAS No:147127-20-6 [(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid
    Molecular Structure

    Detailed Description

    High purity 98% 1-(6-Aminopurin-9-yl)propan-2-yloxymethylphosphonic acid /Tenofovir Pharmaceutical Intermediates cas:147127-20-6

    Quick detail:

    CAS Registry Number:147127-20-6 purity: 98%
    Molecular Formula:C9H14N5O4P Molecular Weight: 287.21
    ATC code:J05AF07 PubChem:CID 464205
    DrugBank:DB00300 ChemSpider:408154
    ChEMBL:CHEMBL483 NIAID ChemDB:080741
    Synonyms:1-(6-aminopurin-9-yl)propan-2-yloxymethylphosphonic acid;D,L-TENOFOVIR;TENOFOVIR;(R)-9-(2-PHOSPHONYLMETHOXYPROPYL)-ADENINE;(R)-9-(2-Phosphonomethoxypropyl)Adenine;Tenofovir(ForResearchOnly);(R)-PMPA;[[(1R)-2(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic Acid
    Molecular Structure






    Description:

    Tenofovir disoproxil fumarate, marketed by Gilead Sciences under the trade name Viread, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (NRTIs), which block reverse transcriptase, a crucial virus enzyme in human immunodeficiency virus 1 (HIV-1) and hepatitis B virus infections.

    Application:

    1.Tenofovir is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients 2 years of age and older.[2] This indication is based on analyses of plasma HIV-1 RNA levels and CD4 cell counts in controlled studies of tenofovir in treatment-naive and treatment-experienced adults.

    2.Tenofovir is indicated for the treatment of chronic hepatitis B in adults and pediatric patients 12 years of age and older

    Specification:

    Product Name:
    Tenofovir [PMPA]

    CAS NO.:
    147127-20-6

    MF:
    C9H14N5O4P

    MW:
    287.2

    Standard:
    In-house. FDA;USDMF

    Appearance:
    White to off white powder

    Status:
    Commercial

    Application:
    Antivirus, Anti-HIV



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  • 1-(6-Aminopurin-9-yl)propan-2-yloxymethylphosphonic acid /Tenofovir
  • 1-(6-Aminopurin-9-yl)propan-2-yloxymethylphosphonic acid /Tenofovir