Benzocaine
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Molecular Structure
Detailed Description
Benzocaine
Attention: The COA Provided--Factory Direct Sales
Specifications:
Synonyms: AETHOFORM;anesthesin;AKOS BBS-00003658;4-AMINOBENZOIC ACID ETHYL ESTER;LABOTEST-BB LTBB000527;H-4-ABZ-OET;ETHYL 4-AMINOBENZOATE;ETHYL P-AMINOBENZOATE
Attention: The COA Provided--Factory Direct Sales
CAS number: 94-09-7
EINECS: 202-303-5
Molecular formula: C9H11NO2
Molecular weight: 165.19
Purity: 99%
Properties: white crystalline powder; odorless, slightly bitter taste, then have numbness; when being light yellow.
Package: 25kg/cardboard
Standard: USP
Pharmaceutical Grade
The page number: 2000 two edition 371
This product is amino ethyl benzoate. According to the dry matter calculation, C9H11NO2 containing not less than 99%.
This product is in ethanol, chloroform soluble in fatty oil, slightly soluble in water, soluble in dilute acid solution;
The melting point of the product of the melting point (Appendix VI C) is 88 to 91 DEG c.
[identification]
(1) the differential response to this product display aromatic amines (Appendix III) first.
(2) take this product about 0.1g, addition of sodium hydroxide solution 5ml, boiling, namely ethanol production; iodine test solution, heating,
That is generating the yellow precipitate, odor and the occurrence of iodoform.
(3) the goods should be light absorption pattern contrast pattern of (spectrum set of 237 plans) consistent.
[check] acidity to take this product 1.0g, plus neutral alcohol (of phenolphthalein indicator solution was neutral) dissolved in 10ml,
Add 2 drops of phenolphthalein indicator solution and titration with sodium hydroxide solution (0.1mol/L) 0.10ml, should damask.
Chloride to take this product 0.2g, add 5ml of ethanol dissolved, add 3 drops of dilute nitric acid and silver nitrate solution 3 drops, not immediate turbidity.
Loss on drying take this product, the phosphorus pentoxide dryer for drying to constant weight, lose weight shall not exceed 0.5% (Appendix VIII L).
Residue on ignition to take this product 1.0g, to check (Appendix VIII N), remaining residue shall not exceed 0.1%.
Heavy metals to take residue left under the debris, according to inspection (Appendix VIII H second method), containing heavy metal
[content determination] take this product about 0.35g, accurately weighed, as dead stop titration (Appendix VII A), with nitrite
Sodium acid titrating solution (0.1mol/L) titration. Each 1ml sodium nitrite titrimetric solution (0.1mol/L) is equivalent to 16.52mg C9H11NO2. [category] local anesthetics.
[storage] shading, sealing preservation.
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- Benzocaine
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