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| Produktsname: | tris(2-methylphenyl) phosphate |
| CAS Registry Number: | 78-30-8 |
| EINECS: | 201-103-5 |
| Synonyme: | Triorthocresyl phosphate; TOCP;o-Tolyl phosphate;tris(2-methylphenyl) phosphate; Tri-o-tolyl phosphate; o-Cresyl phosphate; TOTP; 78-30-8; |
| Molecular Structure: |
 |
| Molecular Formula: | C21H21O4P |
| Molecular Weight: | 368.362802 |
| Dichte: | 1.2 |
| Boiling Point: | 410 °C |
| Schmelzpunkt: | -25 °C |
| Flash Point: | 225 °C |
| Brechungsindex: | 1.558-1.561 |
| Risiko-Codes: | 51/53-39/23/24/25 |
| S-Sätze: | Poison by subcutaneous, intramuscular, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. Most of the cases of tri-o-cresyl phosphate poisoning have followed its ingestion. In 1930, some 15,000 persons were affected in the United States, and of these, 10 died. The responsible material was found to be an alcoholic drink known as Jamaica ginger, or “jake.” This beverage had been adulterated with about 2% of tri-o-cresyl phosphate. The affected persons developed a polyneuritis, which progressed, in many cases, with degeneration of the peripheral motor nerves, the anterior horn cells, and the pyramidal tracts. Sensory changes were absent. Since 1930 there have been several other outbreaks of poisoning following ingestion of the material. Tri-o-cresyl phosphate is more toxic than the m-form, and much more so than tri-p-cresyl phosphate or triphenyl phosphate. Experimental reproductive effects. Combustible when exposed to heat or flame |
| Gefahrensymbole: | Toxic by ingestion and skin absorption. The o- isomer is highly toxic. TLV: 0.1 mg/m3 (skin); Not Classifiable as a Human Carcinogen. |