An anaplastic lymphoma kinase (ALK)-positive inhibitor used for the treatment of non-small cell lung cancer (NSCLC). It less potently inhibits IGF-1R, InsR, and STK22D and IC50 value is 8, 7, and 23 nM. LDK378 is also minimally effective against a panel of other kinases. In Sep 2016, Interim adverse events and efficacy data from phase III ASCEND-4 trial in non small cell lung cancer released by Novartis. In Oct 2016, efficacy data from the phase III ASCEND-3 and ASCEND-5 trial in non small cell lung cancer was presented.https://www.bocsci.com/ceritinib-cas-1032900-25-6-item-462148.html
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Basic Information
Business Type: Manufacturer
Product/Service (We Buy): 101 - 500 People
Year Established: 2005
Number of Employees: 101 - 500 People
Trade & Market
Main Markets: North America,Southeast Asia,Mid East,South America,Africa,Eastern Asia,Eastern Europe,Oceania,Western Europe
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