VE-822VE-822 is a selective ATR inhibitor with an Ki value of 0.2 nM, >150 fold selectivity over ATM (Ki=34 nM), DNA-PK (Ki >4 uM) and mTOR (Ki >1 uM).
IC50 Value: 0.2 nM (Ki); 19 nM (Cell IC50) [1]
Target: ATR
in vitro: VE-822, a close analog of VE-821, has increased potency against ATR retaining the excellent ATR selectivity pro?le.
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