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EPZ004777

  • Purity: >98%
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

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  • Product Name.:EPZ004777
  • CAS No: 1338466-77-5

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EPZ004777EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.

IC50 value: 0.4 nM [1]

Target: DOT1L

in vitro: EPZ004777 selectively inhibits cellular H3K79 methylation and inhibits expression of key MLL fusion target genes.

Target:NMDA Receptor

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EPZ-6438

CAS No: 1403254-99-8

Purity: >98%

Min quantity: null null

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Description: EPZ-6438 EPZ-6438 is a potent, selective, and orally bioavailable small-molecule inhibitor of EZH2 enzymatic activity with Ki value of 2.5±0.5 nM. IC50 Value: 2.5±0.5 nM (PRC2-containing wild-type EZH2) [1] Target: EZH2; HMTase in vitro: EPZ-6438 inh...

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