Product Name:Methylhexanamine,dimethylamylamine,methylhexamine,DMAA
Alias:1,3-dimethylpentylamine hydrochloride,2-amino-4-methylhexane hydrochloride
CAS Registry Number:13803-74-2
Molecular Formula:C7H18ClN
Molecular Weight:151.68
Appearance:White Crystalline powder
Grade:Pharmaceutical Grade
Methylhexanamine is synthesized by reacting 4-methylhexanone-2 with hydroxylamine, which converts the 4-methylhexanone-2 to 4-methylhexanone-2 oxime, which is reduced with hydrogen by means of a catalyst; the resulting methylhexanamine can be purified by distillation.
A large number of supplements focusing on fat loss and workout energy (thermogenic or general-purpose stimulants) now use the ingredient in concert with other substances such as caffeine, a combination similar to the combination of ephedrine and caffeine.
Methylhexanamine is an indirect sympathomimetic drug that constricts blood vessels and thus has effects on the heart, lungs, and reproductive organs it also causes bronchodilation, inhibits peristalsis in the intestines, and has diuretic effects.Most studies have been done on pharmacological effects when the drug is inhaled; our understanding of what methylhexanamine does when taken orally are mostly based on extrapolating from the activities of similar compounds.A 2013 review concluded that: "Pharmacological effects after oral intake can be expected on the lungs (bronchodilation) and the nasal mucosa following a single oral dose of about 4-15 mg. Pharmacological effects on the heart can be expected following a single oral dose of about 50-75 mg. Pharmacological effects on the blood pressure can be expected after a single oral dose of about 100 mg. Because of the long half-life, there is a risk that repeated doses within 24-36 hours could lead to steadily stronger pharmacological effects (build-up).
Dimethylamylamine is a drug made synthetically in a laboratory. It was originally used as a nasal decongestant. Today, dimethylamylamine is sold as a dietary supplement used for attention deficit-hyperactive disorder (ADHD), weight loss, improving athletic performance, and body building.
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