1-(6-Aminopurin-9-yl)propan-2-yloxymethylphosphonic acid /Tenofovir

High purity 98% 1-(6-Aminopurin-9-yl)propan-2-yloxymethylphosphonic acid /Tenofovir Pharmaceutical Intermediates cas:147127-20-6

Quick detail:

CAS Registry Number:147127-20-6 purity: 98%
Molecular Formula:C9H14N5O4P Molecular Weight: 287.21
ATC code:J05AF07 PubChem:CID 464205
DrugBank:DB00300 ChemSpider:408154
ChEMBL:CHEMBL483 NIAID ChemDB:080741
Synonyms:1-(6-aminopurin-9-yl)propan-2-yloxymethylphosphonic acid;D,L-TENOFOVIR;TENOFOVIR;(R)-9-(2-PHOSPHONYLMETHOXYPROPYL)-ADENINE;(R)-9-(2-Phosphonomethoxypropyl)Adenine;Tenofovir(ForResearchOnly);(R)-PMPA;[[(1R)-2(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic Acid
Molecular Structure






Description:

Tenofovir disoproxil fumarate, marketed by Gilead Sciences under the trade name Viread, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (NRTIs), which block reverse transcriptase, a crucial virus enzyme in human immunodeficiency virus 1 (HIV-1) and hepatitis B virus infections.

Application:

1.Tenofovir is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients 2 years of age and older.[2] This indication is based on analyses of plasma HIV-1 RNA levels and CD4 cell counts in controlled studies of tenofovir in treatment-naive and treatment-experienced adults.

2.Tenofovir is indicated for the treatment of chronic hepatitis B in adults and pediatric patients 12 years of age and older

Specification:

Product Name:
Tenofovir [PMPA]

CAS NO.:
147127-20-6

MF:
C9H14N5O4P

MW:
287.2

Standard:
In-house. FDA;USDMF

Appearance:
White to off white powder

Status:
Commercial

Application:
Antivirus, Anti-HIV



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