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CAS No:155148-31-5 1,1'-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane]
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Plerixafor (octahydrochloride)

  • CAS No.: 155148-31-5
  • Purity: >98%
  • Weight: 502.78
  • Formula: C28H54N8
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

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Item specifics

  • Product Name.:Plerixafor (octahydrochloride)
  • CAS No: 155148-31-5
  • Weight: 502.78
  • Formula: C28H54N8
  • Boiling Point: 657.5°Cat760mmHg
  • Density: 0.962g/cm3

Details

Plerixafor (octahydrochloride)Plerixafor octahydrochloride(AMD3100 8HCL) is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively.

IC50 value: 44 nM (CXCR4); 5.7 nM (CXCL12-mediated chemotaxis)

Target: CXCR4

in vitro: Plerixafor inhibits CXCL12-mediated chemotaxis with a potency lightly better than its affinity for CXCR4.

Target:PDK-1

Product Links:http://www.medchemexpress.cn/plerixafor-octahydrochloride.html

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CAS No:155148-31-5 1,1'-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane]

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