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AZD-8835

  • Purity: 98%
  • Price: USD 250~1670/Kilograms
  • Place of Orign: wuhan,Hubei,China
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  • Product Name.:AZD-8835
  • CAS No: 1620576-64-8

Details

AZD8835 is a selective, oral inhibitor of PI3K isoforms and with the following activity in enzymatic assays: PI3K C IC50 = 6nM (equipotent vs wt and E545K / H1047R mutants); PI3K C IC50 = 6nM; PI3K C IC50 = 90nM; PI3K C IC50 = 431nM. Inhibition of signalling in cells (pAKT endpoint): PI3K C IC50= 57nM; PI3K C IC50= 49nM; PI3K C IC50= 3.6M; PI3K - IC50= 532nM

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