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Doxorubicin hydrochloride

  • CAS No.: 25316-40-9
  • Purity: 99
  • Min quantity: 1 Kilograms
  • Price: USD 1~5/Kilograms
  • Place of Orign: Zhuzhou,Hunan,China
Ms.Amy Yu

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Item specifics

  • Product Name.:Doxorubicin hydrochloride
  • CAS No: 25316-40-9
  • Weight: 579.99
  • Formula: C27H29NO11.HCl
  • Melting Point: 216 °C (dec.)(lit.)
  • Boiling Point: 810.3 °C at 760 mmHg

Details

English name: Doxorubicin Hydrochloride for Injection
Latin name: Doxorubicini Hydrochloridum Pro Injectione
CAS number: 25316-40-9
Molecular Formula:C27H29NO11·HCI
Molecular weight: 579.99
Melting point: 216°C
Traits
This product is orange-red loose block or powder, soluble in water, DMSO, tetrahydrofuran, alcohol. Insoluble in acetone, chloroform, benzene, ether. Solubility in water 10mg/ml.
This product can be combined with glucose and sodium chloride infusion; it can also be combined with some anti-tumor drugs.
Pharmacological effects
Doxorubicin produces a wide range of biochemical effects on the body. Has a strong cytotoxic effect. Its mechanism of action is mainly that the mold of Bacillus is inserted into DNA to inhibit the synthesis of nucleic acid.
Absorption, distribution, excretion
Adriamycin quickly disappears in plasma after intravenous injection. Widely distributed in the liver, spleen, kidney, lung and heart. This product is mainly metabolized in the liver, and about half is excreted in the bile. Urinary excretion is about 4-5%, and liver insufficiency will result in slower excretion. This product cannot pass the blood-brain barrier.
Indications
This product is suitable for breast cancer, lung cancer, soft tissue tumors, osteosarcoma, bladder cancer, testicular cancer, thyroid cancer, neuroblastoma, nephroblastoma, malignant lymphoma and acute leukemia, can also be used for liver cancer, gastric cancer, ovarian cancer Cervical cancer, head and neck cancer, multiple myeloma, pancreatic cancer, esophageal cancer, and endometrial cancer.
Doxorubicin hydrochloride

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