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Chlorogenic acid

  • CAS No.: 327-97-9
  • Purity: 5%-98%Chlorogenic Acid
  • Min quantity: 5000 Kilograms
  • Price: USD 10~1000/Kilograms
  • Place of Orign: Changde,Hunan,China
Ms.Cherry Chan

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Item specifics

  • Product Name.:Chlorogenic acid
  • CAS No: 327-97-9
  • Weight: 354.31
  • Formula: C16H18O9
  • Melting Point: 205-209 ºC
  • Boiling Point: 665°Cat760mmHg
  • Density: 1.65g/cm3

Details

Chlorogenic Acid Extract Powder Eucommia Extract Powder


Description Of Eucommia Extract Pure Chlorogenic Acid

Product Name
Eucommia Ulmoides Extract Pure Chlorogenic Acid
Latin Name:Eucommia Ulmoides Oliv.
Family:Eucommia Ulmoides
Part Used: Leaves
Active Ingredients: Chlorogenic Acid
Specs Available: 10% 20% 25%
Appearance:Brown yellow fine powder

What is 5~98% Eucommia Extract Powder/ Pure Chlorogenic acid?
Chlorogenic acids are cholegogues; their regular ingestion helps the flow of bile and thus reduces the adverse effects of bile stagnation. Chlorogenic acids (see basic structure, below) are found in all higher plants and are understood to have a role in the plant's response to stress, particularly to damage such as breaking of leaves and flowers or nicking the skin of fruits (1). The quantities present in most plants are miniscule, and thus they do not play an important part in human diet or herbal medicines. However, a few plants accumulate chlorogenic acids in quantities sufficient to have a physiological effect. The

primary dietary source of chlorogenic acid is coffee; the green coffee beans typically contain 6-7% of this component (range: 4-10%); roasted coffee beans contain somewhat less, as the roasting transforms chlorogenic acids into other molecules, which may still retain the same functions.

Quality Eucommia Extract Powder Pure Chlorogenic Acid
1).Ash: 0.2% max
2).Moisture:1%max
3).Heavy metal:2ppm max
4).Pb:2ppm max
5).As:2ppm max
6).Size:80 Mesh

Microbiological Eucommia Extract Powder Pure Chlorogenic Acid
1).Total plate count: 1000cfu/g max
2).Yeast & Mold:100cfu/g max
3).E.Coli:Negative
4).Salmonella:Negative
5).Staphylococcus:Negative

Application Of Eucommia Extract Powder Pure Chlorogenic Acid
1).Eucommia Extract Chlorogenic Acid are applied in anti-hypertensive effect
2). Eucommia Extract Chlorogenic Acid are applied in anti-tumor effect
3). Eucommia Extract Chlorogenic Acid are applied in kidney, and enhance immune function
4). Eucommia Extract Chlorogenic Acid are applied in anti-oxidation, anti-aging, anti-aging musculoskeletal
5).Eucommia Extract Chlorogenic Acid are applied in anti-bacterial, anti-virus
6).Eucommia Extract Chlorogenic Acid also have other
functions:diuretic,choleretic,lowering blood pressure, miscarriage.

Main Functions Eucommia Extract Powder Pure Chlorogenic Acid
1. Eucommia Extract Powder has antihypertensive effects: Chlorogenic acid has significant antihypertensive effect, which is smooth, and non-toxic without side effects.
2. Eucommia Extract Powder Chlorogenic Acid as anti-tumor effects: Modern
pharmacological experiments show that chlorogenic acid has the effects of anti-cancer and tumor suppressor.
3. Eucommia Extract Powder Chlorogenic Acid has the effects of strengthening Kidney and enhancing immune function: experimental results show that chlorogenic acid can excite pituitary and adrenal cortex system and can enhance the function of the adrenal cortex.
4. Eucommia Extract Powder Chlorogenic Acid is a antioxidant, anti-aging, against free radicals, promoting metabolism
5. Eucommia Extract Powder Chlorogenic acid has antibacterial, anti-inflammatory effects. It decreases blood pressure and increases white blood cells and gastric peristalsis and secretion significantly.

Health Benefits of Eucommia Extract Chlorogenic Acid
1. Anti oxidative effects of Eucommia Extract Chlorogenic Acid
In the investigation of the impact of consumption of a coffee containing high levels of chlorogenic acids on the oxidation of proteins, DNA and membrane lipids; additionally,other redox biomarkers were monitored in an intervention trial, found that the oxidation of DNA, lipids and proteins associated with the incidence of various diseases and the protection against their oxidative damage may be indicative for beneficial health effects of coffee.

2. Hepatoprotective effects of Eucommia Extract Chlorogenic Acid
In the investigation of the potential protective effects of chlorogenic acid (CGA) on acute liver injury caused by lipopolysaccharide (LPS) in mice, found that CGA also decreased the elevated plasma levels of ALT and AST. At the transcriptional level, CGA pretreatment suppressed hepatic mRNA expression of toll-like receptor 4 (TLR4), TNF-alpha and NF-kappaB p65 subunit. In contrast, mRNA level of the transcriptional coactivator PGC-1alpha was restored by CGA. Finally, CGA reduced the phosphorylation of NF-kappaB p65 subunit in the liver.


3. Anti-obesity of Eucommia Extract Chlorogenic Acid
in the investigation of the efficacy of chlorogenic acid on altering body fat in high-fat diet(37% calories from fat) induced-obese mice compared to caffeic acid. Caffeic acid or chlorogenic acid was supplemented with high-fat diet at 0.02% (wt/wt) dose, found that Caffeic acid and chlorogenic acid significantly inhibited fatty acid synthase, 3-hydroxy-3-methylglutaryl CoA reductase and acyl-CoA:cholesterol acyltransferase activities, while they increased fatty acid beta-oxidation activity and peroxisome proliferator-activated receptors alpha expression in the liver compared to the high-fat group, and concluded that
caffeic acid and chlorogenic acid improve body weight, lipid metabolism and obesity-related hormones levels in high-fat fed mice. Chlorogenic acid seemed to be more potent for body weight reduction and regulation of lipid metabolism than caffeic acid.

4. Anti-inflammatory effects of Eucommia Extract Chlorogenic Acid
In the assessment in vivo of the anti-inflammatory and antinociceptive activities of the aerial part and root extracts of Scorzonera acuminata, Scorzonera cana var. alpina,Scorzonera cana var. jacquiniana, Scorzonera cana var. radicosa, Scorzonera cinerea,Scorzonera eriophora, Scorzonera incisa, Scorzonera laciniata ssp. laciniata, Scorzonera parviflora and Scorzonera sublanata and theirs effect against inflammation and to relieve pain, found that Scorzonera cana var.

5. Antioxidants of Eucommia Extract Chlorogenic Acid
In the study of the chemical composition and the antioxidant activity of spent coffee grounds and coffee husks extracts, obtained by supercritical fluid extraction (SFE) with CO(2) and with CO(2) and co-solvent, found that the best antioxidant activity was showed by coffee husk extracts obtained by LPE. The quantification and the identification of the extracts were accomplished using HPLC analysis. The main compounds identified were caffeine and chlorogenic acid for the supercritical extracts from coffee husks.

6. Antitussive of Eucommia Extract Chlorogenic Acid
In the investigation of the orally administrated the water extracts in mice. Ammonia induced mice coughing model was used to evaluate the antitussive activity, found that only flower bud can be used as the antitussive and expectorant herbal drug. The high concentration of chlorogenic acid, 3,5-dicaffeoylquinic acid, rutin in flower buds may be related with the antitussive and expectorant effects of Flos Farfara. To guarantee the clinical effect, rachis should be picked out before use.

7. Rheumatoid Arthritis of Eucommia Extract Chlorogenic Acid
In the investigation the antiarthritic activities of this compound in adjuvant induced-arthritis in male Wistar rats, and exploration of the underlying mechanisms of actions in view of immunological responses, found that CGA efficiently suppressed CD80/86 but failed to bring any changes in the CD28 count, whereas ibuprofen (standard drug) resulted in highly significant inhibition of both.

Cherry Chan

Tel:13501541862

Skype: qiurongchan

Email: worldwellbeing02(at)gmail.com
Chlorogenic acid

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