L-Thyroxine / Epinephrine Hydrochloride

Quick Detail:

Product name
L-Thyroxine Factory Supplying
Other name
Levothyroxine; L-Epinephrine HCl; epinephrine hydrochloride; L-adrenaline hydrochloride; (R)-adrenaline hydrochloride
CAS register number
51-48-9
EINECS
200-101-1
Molecular formula
C15H11I4NO4
Molecular weight
776.87
Molecular structure
51-48-9 Anesthetic Anodyne Powder L-Thyroxine / Epinephrine Hydrochloride
Melting point
235°C
Assay
99%

Product description:

Levothyroxine (INN, USAN) or L-thyroxine is a synthetic thyroid hormone that is chemically identical to thyroxine (T4), which is naturally secreted by the follicular cells of the thyroid gland. It is used to treat thyroid hormone deficiency, and occasionally to prevent the recurrence of thyroid cancer. Like its naturally secreted counterpart, levothyroxine is a chiral compound in the L-form. The related drug dextrothyroxine (D-thyroxine) was used in the past as a treatment for hypercholesterolemia (elevated cholesterol levels) but was withdrawn due to cardiac side effects.

Levothyroxine is typically used to treat hypothyroidism, and is the treatment of choice for patients with hypothyroidism, who often require lifelong thyroid hormone therapy. It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing. Levothyroxine is also used as interventional therapy in patients with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion. In 1992, President George H.W. Bush told television host Larry King that he had been prescribed levothyroxine as part of a treatment regimen for Graves' disease.
Side effects: This medication should not be used for weight loss. Normal doses of this medication will not work for weight loss, and large doses of this medication may cause serious, possibly fatal side effects, especially when taken with diet pills.

COA and HPLC:

COA:

Product name
L-Thyroxine
Appearance
White crystalline powder
Assay(*)
98～101.0%
99.3%
Identification
By UV, To match with working standard
Complies
Related Substances
Not more than the reference solution (0.05%)
Complies
Heavy metals
≤10ppm
10ppm
Loss on drying
<0.5%
0.15%
Resiue on ignition
≤0.1%
0.05%
Melting
235°C
Complies


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