Product Name: Pimaricin
Synonyms: NATAMYCIN;PIMAFUCIN;PIMARICIN;PIMARICIN, STREPTOMYCES CHATTANOOGENSIS;antibiotica-5283;cl12,625;delvocid;delvolan
CAS: 7681-93-8
MF: C33H47NO13
MW: 665.73
EINECS: 231-683-5
Product Categories: Food & Feed ADDITIVES;Antifungal (Topical);Intermediates & Fine Chemicals;Pharmaceuticals;food additives;ERGOSTAT;antibiotic
Mol File: 7681-93-8.mol
mp :2000C (dec)
density :1.0 g/mL at 20 °C(lit.)
storage temp. : 2-8°C
form : aqueous suspension
Stability: Light sensitive
Chemical Properties :White to Off-White Solid
Usage :Polyene antifungal antibiotic
Usage :analgesic, antimigraine
Usage :Pimaricin is a macrocyclic tetraene originally isolated from Streptomyces natalensis in 1957. Pimaricin exhibits broad spectrum antifungal activity against yeast and filamentous fungi by binding specifically to ergosterol to block fungal growth. Unlike the related polyenes, nystatin and filipin, pimaricin does not change the permeability of the plasma membrane. Pimaricin is used in the food industry for surface treatment of cheeses as a mould inhibitor.
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