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CAS No:842133-18-0 (2S,3R,4R,5S,<br />6R)-2-[3-[[5-(4-fluorophenyl)thiophen-2-yl]methyl]-4-methylphenyl]-6-<br />(hydroxymethyl)oxane-3,4,5-triol
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Canagliflozin

  • CAS No.: 842133-18-0
  • Purity: >98%
  • Weight: 444.515703
  • Formula: C24H25FO5S
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

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Item specifics

  • Product Name.:Canagliflozin
  • CAS No: 842133-18-0
  • Weight: 444.515703
  • Formula: C24H25FO5S
  • Boiling Point: 642.9±55.0 °C at 760 mmHg
  • Density: 1.364

Details

CanagliflozinCanagliflozin(JNJ 28431754; TA 7284) is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM, exhibits 413-fold selectivity over hSGLT1.

IC50 value: 2.2 nM

Target: SGLT2

Canagliflozin(JNJ 24831754ZAE; JNJ 28431754; JNJ 28431754AAA; TA 7284) is an experimental drug being developed by Johnson & Johnson for the treatment of type 2 diabetes.Canagliflozin(JNJ 24831754ZAE; JNJ 28431754; JNJ 28431754AAA; TA 7284) is an inhibitor of subtype 2 sodium-glucose transport protein (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney.

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CAS No:842133-18-0 (2S,3R,4R,5S,<br />6R)-2-[3-[[5-(4-fluorophenyl)thiophen-2-yl]methyl]-4-methylphenyl]-6-<br />(hydroxymethyl)oxane-3,4,5-triol

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