CAS 84371-65-3 Anti Estrogen Steroids Mifpristone Powder Anti Aging

Detailed Product Description
Product Name: E: Mifpristone Appearance: Light Yellowish Powder
Export Markets: Global Purity:: 99%
Standard: Enterprise Standard Policy: Re-Shipping Policy
Supply: In Stock Trade Term: FOB,CIF, EXW
CAS 84371-65-3 Anti Estrogen Steroids Mifpristone Powder Anti Aging


Product Details:

Product name: Mifpristone
CAS NO.: 84371-65-3
Molecular Formular:C29H35NO2
Purity:99%
Character: Light Yellowish powder
Standard:USP
CAS 84371-65-3 Anti Estrogen Steroids Mifpristone Powder Anti Aging

Description:

Mifepristone (or RU-486) is a synthetic, steroidal antiprogestogen and antiglucocorticoid drug. It is a 19-norsteroid with substitutions at positions C11 and C17 (17β-hydroxy-11β-(4-(dimethylamino)phenyl)-17α-(1-propynyl)estra-4,9-dien-3-one), which antagonizes cortisol action competitively at the receptor level.
Mifepristone is a low efficacy partial agonist of the progesterone receptor used as an abortifacient in the
first months of pregnancy, and in smaller doses as an emergency contraceptive. It is also a glucocorticoid receptor antagonist to a lesser extent, and has occasionally been used in refractory Cushing's
syndrome (due to ectopic/neoplastic ACTH/cortisol secretion). During early trials, it was known as
RU38486 or simply RU486, its designation at the Roussel Uclaf company, which designed the drug. The
drug was initially made available in France, and other countries then followed often amid controversy. It is marketed under tradenames Korlym and Mifeprex, according to FDA Orange Book.

Applications:

Mifepristone is approved for use in the United States and the EU for the treatment of Cushing's syndrome via a patented preparation manufactured by Corcept Therapeutics.

Other medical applications of mifepristone studied in clinical trials include regular long-term use as an oral contraceptive, and treatment of HIV infection, uterine fibroids, endometriosis, major depression with psychotic features, bipolar depression and disorders causing cognitive dysfunction, post-traumatic stress disorder, chronic multisymptom illness, glaucoma, meningiomas, breast cancer, ovarian cancer, and prostate cancer.

CAS 84371-65-3 Anti Estrogen Steroids Mifpristone Powder Anti Aging

Specifications :

TEST ITEMS
SPECIFICATION
RESULTS
Description
: pale yellow crystalline powder

Assay(by TLC)
: ≥ 98.5%
99.50%
Melting Point
: 192~196 °C
192~196 °C
Loss On Drying
: ≤0.5%
0.1%
Specific Rotation
: +124~ +129°
+127.1°(C=0.5CH2Cl2)

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CAS 84371-65-3 Anti Estrogen Steroids Mifpristone Powder Anti Aging

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