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Organic Intermediates
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Ibrutinib
936563-96-1
Ibrutinib is a small-molecule inhibitor of Bruton's tyrosine kinase (BTK). It binds to BTK to suppress both B-cell activation and B-cell-mediated signaling, and is approved for the treatment of B cell cancers, including mantle cell lymphoma, chronic ...
Min. Order:
10 null
BOC Sciences
[Manufacturer]
Tel: 1-631-4854226
Fax: 1-631-6147828
Address: Ramsey Road Shirley,New YorkUnited States
Ceritinib
1032900-25-6
An anaplastic lymphoma kinase (ALK)-positive inhibitor used for the treatment of non-small cell lung cancer (NSCLC). It less potently inhibits IGF-1R, InsR, and STK22D and IC50 value is 8, 7, and 23 nM. LDK378 is also minimally effective against a pa...
Min. Order:
10 null
BOC Sciences
[Manufacturer]
Tel: 1-631-4854226
Fax: 1-631-6147828
Address: Ramsey Road Shirley,New YorkUnited States
Nintedanib
656247-17-5
Nintedanib is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM. It is used for the treatment of pulmonary fibrosis, systemic sclerosis-associated interst...
Min. Order:
10 null
BOC Sciences
[Manufacturer]
Tel: 1-631-4854226
Fax: 1-631-6147828
Address: Ramsey Road Shirley,New YorkUnited States
Midostaurin
120685-11-2
Midostaurin is a multi-target protein kinase inhibitor being investigated for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). https://www.bocsci.com/midostaurin-cas-120685-11-2-item-162132.html
Min. Order:
10 null
BOC Sciences
[Manufacturer]
Tel: 1-631-4854226
Fax: 1-631-6147828
Address: Ramsey Road Shirley,New YorkUnited States
Trametinib
871700-17-3
A MEK inhibitor that suppresses MEK1 and MEK2 with IC50 of 0.92 and 1.8 nM and no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2. It has been approved by FDA, in combination with Tafilnar, for the treatment of metastatic anaplastic thyro...
Min. Order:
10 null
BOC Sciences
[Manufacturer]
Tel: 1-631-4854226
Fax: 1-631-6147828
Address: Ramsey Road Shirley,New YorkUnited States
Cefoperazone
62893-19-0
A third-generation cephalosporin antibiotic effective in the treatment of Pseudomonas infections. It has been used to treat respiratory tract infections, peritonitis, skin infections, endometritis, and bacterial septicemia. https://www.bocsci.com/cef...
Min. Order:
10 null
BOC Sciences
[Manufacturer]
Tel: 1-631-4854226
Fax: 1-631-6147828
Address: Ramsey Road Shirley,New YorkUnited States
Nebivolol
118457-14-0
Nebivolol, a highly selective β1-adrenergic receptor inhibitor, has vasodilatory effect so that could be effective against hypertension. It was just withdrawed a Phase II/III trial for Hypertension in patients with chronic obstructive pulmonary dise...
Min. Order:
10 null
BOC Sciences
[Manufacturer]
Tel: 1-631-4854226
Fax: 1-631-6147828
Address: Ramsey Road Shirley,New YorkUnited States
Nilotinib
641571-10-0
Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM. It is under investigation as a possible treatment for chronic myelogenous leukemia (CML). https://www.bocsci.com/nilotinib-cas-641571-10-0-item-84-74229.html
Min. Order:
10 null
BOC Sciences
[Manufacturer]
Tel: 1-631-4854226
Fax: 1-631-6147828
Address: Ramsey Road Shirley,New YorkUnited States
Natamycin
7681-93-8
Natamycin is a naturally occurring antifungal agent produced during fermentation by the bacterium Streptomyces natalensis with a MIC (minimum inhibitory concentration) of less than 10 ppm for most molds. It is especially effective against Aspergillus...
Min. Order:
10 null
BOC Sciences
[Manufacturer]
Tel: 1-631-4854226
Fax: 1-631-6147828
Address: Ramsey Road Shirley,New YorkUnited States
Cefonicid
61270-58-4
Cefonicid is a second-generation cephalosporin antibiotic used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections. It works by suppressing cell wall synthesis. https://www.bocsci.com/cefonicid-cas-61...
Min. Order:
10 null
BOC Sciences
[Manufacturer]
Tel: 1-631-4854226
Fax: 1-631-6147828
Address: Ramsey Road Shirley,New YorkUnited States
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