Home > Name List By 6 > 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol

CAS No 1491-59-4 , 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol

  • Name: 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol
  • Synonyms: Sinerol; Navisin; Oxylazine; Rhinofrenol; Oximetazolinum; Hazol;Oxymethazoline;6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol; Nafrine; Iliadin;
  • CAS Registry Number:
  • Transport: 3249
  • Melting Point: 182 ºC
  • Density: 1.08 g/cm3
  • Safety Statements: Poison by ingestion and subcutaneous routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
  • EINECS: 216-079-1
  • Molecular Weight: 260.37456
  • InchiKey: WYWIFABBXFUGLM-UHFFFAOYSA-N
  • InChI: InChI=1S/C16H24N2O/c1-10-8-13(16(3,
    4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)
  • Molecular Formula: C16H24N2O
  • Molecular Structure:CAS No:1491-59-4 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol
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1491-59-4 oxymetazoline

  • IUPAC NAME-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)- 2,4-dimethyl-6-tert-butyl-phenol MOLECULAR FORMULA-C16H24N2O MOLAR MASS-260.375?g·mol?1 xymetazoline is a selective alpha-1 agonist and partial alpha-2 agonist topical decongestant
  • India Swapnroop Drugs and Pharmaceuticals [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641870
  • Address: Harsool aurangabad,maharashtraIndia
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1491-59-4 oxymetazoline

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1491-59-4 oxymetazoline

  • United States Waterstone Technology LLC [Manufacturer]
  • Tel: 317-644-0862/ 317-218-7464
  • Fax: 317-569-8068
  • Address: Waterstone Technology LLC
    12202 Hancock Street
    Carmel, IN. 46032 null,nullUnited States
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1491-59-4 Oxymetazoline

  • China Xingcheng Chempharm Co., Ltd [Manufacturer]
  • Tel: +86-576-88525005/ +86-576-88886292
  • Fax: +86-576-88225056
  • Address: B Area, 10F, Yaoda Mansion, 289, Shifu Road, Taizhou, Zhejiang, China 318000 null,nullChina
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1491-59-4 OXYMETAZOLINE-D4

  • India VARDA Biotech (P) Ltd. [Manufacturer]
  • Tel: +91-22-6693 5686 / 2673 0141 / 2673 4258
  • Fax: +91-22-6693 5687
  • Address: 110 & 111, Kartik Complex
    New link Road, Andheri-(W)
    Mumbai-400053, INDIA. null,nullIndia
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1491-59-4 OXYMETAZOLINE

  • India JAI RADHE SALES null
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. null,nullIndia
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1491-59-4 OXYMETAZOLINE HCL

  • Canada Synth?se AptoChem Inc. [Manufacturer]
  • Tel: 514-496-4252
  • Fax: 514-496-4253
  • Address: Synth?se AptoChem Inc.
    6100 Royalmount Ave
    Montreal, QC
    Canada
    H4P 2R2 null,nullCanada
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1491-59-4 oxymetazoline

  • China shanghai sphchem co.,ltd [Manufacturers]
  • Tel: +86-21-56491756 13512199871
  • Fax: 0
  • Address: NO.133, Wuye, Yangxin Road ,Shanghai China shanghai,shanghai ChinaChina
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1491-59-4 oxymetazoline

  • China Maple Chemical Co.,ltd. [Manufacturer]
  • Tel: 86-574- 87512300
  • Fax: 86-574-82095182
  • Address: No.347,Sanbei Road,Sanbei Town,Cixi ,Zhejiang,China Ningbo,ZhejiangChina
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1491-59-4 Oxymetazoline

  • China Levachem Co. Ltd. [Manufacturers]
  • Tel: 86-25-83247442 / 443 / 445 / 446 / 447
  • Fax: +86-25-83247441
  • Address: 2112, SuNing Universal Mansion, 188 Guangzhou Road, Nanjing-210024, China Nanjing,jiangsuChina
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References of 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol
Title: Oxymetazoline
CAS Registry Number: 1491-59-4
CAS Name: 3-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol
Synonyms: 6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol; 2-(4-tert-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline
Manufacturers' Codes: H-990
Trademarks: Navisin; Hazol; Rhinofrenol; Rhinolitan (3M Pharma); Sinerol; Nezeril (Draco)
Molecular Formula: C16H24N2O
Molecular Weight: 260.37
Percent Composition: C 73.81%, H 9.29%, N 10.76%, O 6.14%
Literature References: Prepd from (4-tert-butyl-2,6-dimethyl-3-hydroxyphenyl)acetonitrile and ethylenediamine: Fruhstorfer, Mueller-Calgan, DE 1117588 (1961 to E. Merck), C.A. 57, 4674a (1962). Toxicity data: Hotovy et al., Arzneim.-Forsch. 11, 1016 (1961).
Properties: Crystals from benzene, mp 181-183°.
Melting point: mp 181-183°
 
Derivative Type: Hydrochloride
CAS Registry Number: 2315-02-8
Trademarks: Afrazine (Schering-Plough); Afrin (Schering-Plough); Iliadin (Meda); Nafrine; Nasivin (Merck KGaA); Oxilin (Allergan); Sinex (LaChartre)
Molecular Formula: C16H24N2O.HCl
Molecular Weight: 296.84
Percent Composition: C 64.74%, H 8.49%, N 9.44%, O 5.39%, Cl 11.94%
Properties: Crystals, dec 300-303°. Freely sol in water, alcohol. Practically insol in ether, chloroform, benzene. LD50 orally in mice: 10 mg/kg (Hotovy).
Toxicity data: LD50 orally in mice: 10 mg/kg (Hotovy)
 
NOTE: Ingredient of Drixin.
Therap-Cat: Adrenergic (vasoconstrictor); nasal decongestant.
Keywords: a-Adrenergic Agonist; Decongestant.