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CAS No 175481-36-4 , (2R)-2-acetamido-N-benzyl-3-methoxypropanamide

  • Name: (2R)-2-acetamido-N-benzyl-3-methoxypropanamide
  • Synonyms: (R)-2-acetamido-N-benzyl-3-methoxypropanamide; 175481-36-4; Harkoseride; Erlosamide;(2R)-2-acetamido-N-benzyl-3-methoxypropanamide; Vimpat;Lacosamide; SPM 927; Erlosamide [INN]; S1253_Selleck;
  • CAS Registry Number:
  • Flash Point: 278.2 °C
  • Boiling Point: 536.4 °Cat760mmHg
  • Density: 1.12 g/cm3
  • Refractive index: 1.52
  • Flash Point: 278.2 °C
  • Molecular Weight: 250.29362
  • InchiKey: VPPJLAIAVCUEMN-GFCCVEGCSA-N
  • InChI: InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-
    7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1
  • Molecular Formula: C13H18N2O3
  • Molecular Structure:CAS No:175481-36-4 (2R)-2-acetamido-N-benzyl-3-methoxypropanamide
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175481-36-4 Lacosamide

  • Product Name: LACOSAMIDE Synonyms: LACOSAMIDE;(2R)-2-acetamido-N-benzyl-3-methoxy-propanamide;(2R)-2-(Acetylamino)-3-methoxy-N-(phenylmethyl)propanamide;ADD 243037;Erlosamide;Harkoseride;SPM 927;(R)-2-Acetamido-N-benzyl-3-methoxypropanamide CAS: 1754...
  • Min. Order: 1
  • FOB Price: USDfalse - false /
  • China Wuhan Senwayer Century Chemical Co.,Ltd [Manufacturer]
  • Tel: 86-027-59707018
  • Address: 20#Xudong Street,Wuhan China Wuhan,HubeiChina
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175481-36-4 Lacosamide

  • China Hangzhou Sage Chemical Co., Ltd. [, Manufacturer]
  • Tel: +86-571-86818502
  • Fax: +86-571-86818503
  • Address: RM501 Tower A, New Youth Plaza, NO.8 Jia Shan Road, Hangzhou, Zhejiang 310014, ,ZhejiangChina
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175481-36-4 Lacosamide

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175481-36-4 Lacosamide

  • China Xingcheng Chempharm Co., Ltd [Manufacturer]
  • Tel: +86-576-88525005/ +86-576-88886292
  • Fax: +86-576-88225056
  • Address: B Area, 10F, Yaoda Mansion, 289, Shifu Road, Taizhou, Zhejiang, China 318000 ,China
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175481-36-4 Lacosamide

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175481-36-4 Lacosamide

  • India JAI RADHE SALES []
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. ,India
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175481-36-4 Lacosamide

  • China Xilin Chemical Group Co., Ltd []
  • Tel: +86-(0)-15527136576
  • Fax: +86-(27)-83820093
  • Address: 16# Luojiashan, Wuchang District, Wuhan, Hubei 430071, ,China
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175481-36-4 LACOSAMIDE-D3

  • India VARDA Biotech (P) Ltd. [Manufacturer]
  • Tel: +91-22-6693 5686 / 2673 0141 / 2673 4258
  • Fax: +91-22-6693 5687
  • Address: 110 & 111, Kartik Complex
    New link Road, Andheri-(W)
    Mumbai-400053, INDIA. ,India
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175481-36-4 Lacosamide

  • China Kouting Chemical Co.,Ltd [Importer/Exporter]
  • Tel: +86-(21)-58116473
  • Fax: +86-(21)-61094103
  • Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318, shanghai,shanghaiChina
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175481-36-4 LACOSAMIDE

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
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References of (2R)-2-acetamido-N-benzyl-3-methoxypropanamide
Title: Lacosamide
CAS Registry Number: 175481-36-4
CAS Name: (2R)-2-(Acetylamino)-3-methoxy-N-(phenylmethyl)propanamide
Synonyms: (R)-N-benzyl-2-acetamido-3-methoxypropionamide; erlosamide; harkoseride
Manufacturers' Codes: ADD-234037; SPM-927
Molecular Formula: C13H18N2O3
Molecular Weight: 250.29
Percent Composition: C 62.38%, H 7.25%, N 11.19%, O 19.18%
Literature References: Functionalized amino acid with demonstrated anticonvulsant and analgesic activity. Prepn: D. Choi et al., J. Med. Chem. 39, 1907 (1996); H. Kohn, WO 9733861; idem, US 5773475 (1997, 1998 both to Research Corp. Technol.). Improved prepn and anticonvulsant activity: S. V. Andurkar et al., Tetrahedron: Asymmetry 9, 3841 (1998). Mode of action study: G. Lees et al., Neuropharmacology 50, 98 (2006). Evaluation in animal models of seizure: G. E. Duncan, H. Kohn, Epilepsy Res. 67, 81 (2005); of inflammatory pain: T. St?hr et al., Eur. J. Pain 10, 241 (2006). Clinical evaluation in neuropathic pain: G. McCleane et al., Neurosci. Lett. 352, 117 (2003). Review of clinical development: C. A. Hovinga, IDrugs 6, 479-485 (2003).
Properties: White solid, mp 143-144°. [a]D23 +16.0° (c = 1 in CH3OH).
Melting point: mp 143-144°
Optical Rotation: [a]D23 +16.0° (c = 1 in CH3OH)
Therap-Cat: Analgesic; anticonvulsant.
Keywords: Analgesic (Non-Narcotic); Anticonvulsant.