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CAS No 18559-94-9 , 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol

  • Name: 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol
  • Synonyms: Buventol; Sultanol; Asmaven; Asthalin; Broncovaleas;4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol; albuterol; Proventil; Aerolin;Salbutamol; Ventolin;
  • CAS Registry Number:
  • Transport: 3249
  • Melting Point: 157-158ºC
  • Density: 1.152 g/cm3
  • Refractive index: 1.566
  • Water Solubility: Solubility: Water: Sparingly Soluble ,Ethanol: Soluble,Chloroform: Very soluble
  • Safety Statements: R22,
  • Hazard Symbols: Xn:Harmful;
  • EINECS: 242-424-0
  • Molecular Weight: 239.31074
  • InchiKey: NDAUXUAQIAJITI-UHFFFAOYSA-N
  • InChI: InChI=1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,
    14-17H,7-8H2,1-3H3
  • Risk Statements: S36,
  • Molecular Formula: C13H21NO3
  • Molecular Structure:CAS No:18559-94-9 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol
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18559-94-9 Albuterol steroids

  • "Albuterol Product Name: salbutamol free base Synonyms: Salbutamol; Albuterol; Levalbuterol; 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol; (L)-Albuterol; 4-[2-(tert-Butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol; Levalbuterol; ...
  • China Maxsource Chem [Manufacturer]
  • Tel: 86-027-83555670
  • Address: No.25, Zhenxing Road, Jianghan District, Wuhan City, Hubei Province, China wuhan,HubeiChina
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18559-94-9 salbutamol

  • IUPAC NAME-(RS)-4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol MOLECULAR FORMULA-C13H21NO3 MOLAR MASS-239.311
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641875
  • Address: Plot No: 04, Mayur Park Road, Harsool Aurangabad,MaharashtraIndia

18559-94-9 Salbutamol

  • IUPAC NAME-(RS)-4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol MOLECULAR FORMULA-C13H21NO3 MOLAR MASS-239.311 Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthm...
  • India Swapnroop Drugs and Pharmaceuticals [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641870
  • Address: Harsool aurangabad,maharashtraIndia
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18559-94-9 SALBUTAMOL

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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18559-94-9 salbutamol free base

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18559-94-9 ALBUTEROL

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
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18559-94-9 salbutamol free base

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi null,ShanXiChina
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18559-94-9 Albuterol

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18559-94-9 Albuterol

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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18559-94-9 ALBUTEROL BASE USP/BP

  • United States Aceto Corp. [Manufacturer]
  • Tel: 516-627-6000
  • Fax: 516-627-6093
  • Address: One Hollow Lane
    Lake Success, NY 11042-1215 null,nullUnited States
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References of 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol
Title: Albuterol
CAS Registry Number: 18559-94-9
CAS Name: a1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol
Synonyms: a1-[(tert-butylamino)methyl]-4-hydroxy-m-xylene-a,a¢-diol; 2-(tert-butylamino)-1-(4-hydroxy-3-hydroxymethylphenyl)ethanol; 4-hydroxy-3-hydroxymethyl-a-[(tert-butylamino)methyl]benzyl alcohol; salbutamol
Manufacturers' Codes: AH-3365
Molecular Formula: C13H21NO3
Molecular Weight: 239.31
Percent Composition: C 65.25%, H 8.84%, N 5.85%, O 20.06%
Literature References: b-Adrenergic agonist. Prepn: L. H. C. Lunts et al., ZA 6705591; eidem, US 3644353 (1968, 1972 both to Allen & Hanburys). Synthesis and structure-activity studies: D. T. Collin et al., J. Med. Chem. 13, 674 (1970). Prepn of isomers: C. J. Hawkins, G. T. Klease, ibid. 16, 856 (1973); R. P. Bakale, Spec. Chem. 15, 249 (1995). Absolute configuration of isomers: D. Hartley, D. Middlemiss, J. Med. Chem. 14, 895 (1971). Pharmacology: R. T. Brittain et al., Nature 219, 862 (1968); V. A. Cullum et al., Br. J. Pharmacol. 35, 141 (1969). Metabolism: L. E. Martin et al., Eur. J. Pharmacol. 14, 183 (1971). Clinical comparison of levalbuterol with racemate: H. S. Nelson et al., J. Allergy Clin. Immunol. 102, 943 (1998). Comprehensive description: H. Y. Aboul-Enein et al., Anal. Profiles Drug Subs. 10, 665-689 (1981). Review of clinical experience in asthma and in preterm labor: A. H. Price, S. P. Clissold, Drugs 38, 77-122 (1989); of toxicology: S. E. Libretto, Arch. Toxicol. 68, 213-216 (1994). Review of clinical trials for add-on therapy to inhaled steroids: S. Shrewsbury et al., Br. Med. J. 320, 1368-1373 (2000).
Properties: Crystalline powder from ethanol-ethyl acetate or ethyl acetate-cyclohexane, mp 151° (Lunts); 157-158° (Collin). Sol in most organic solvents.
Melting point: mp 151° (Lunts); 157-158° (Collin)
 
Derivative Type: Sulfate
CAS Registry Number: 51022-70-9
Trademarks: Aerolin (3M Pharma); Asmaven (APS); Cobutolin (Cox); Ecovent (Ecosol); Loftan (GSK); Proventil (Schering-Plough); Salbulin (3M Pharma); Salbumol (GSK); Salbutard (Lusofarmaco); Salbuvent (Nycomed); Sultanol (GSK); Venetlin (Sankyo); Ventilastin (Viatris); Ventodisks (GSK); Ventolin (GSK); Volmax (GSK)
Molecular Formula: (C13H21NO3)2.H2SO4
Molecular Weight: 576.70
Percent Composition: C 54.15%, H 7.69%, N 4.86%, O 27.74%, S 5.56%
Properties: White crystalline powder. Sol in water; slightly sol in ethanol.
 
Derivative Type: (R)-Form
CAS Registry Number: 34391-04-3
Synonyms: Levalbuterol; levosalbutamol
 
Derivative Type: (R)-Form hydrochloride
CAS Registry Number: 50293-90-8
Trademarks: Xopenex (Sepracor)
Molecular Formula: C13H21NO3.HCl
Molecular Weight: 275.77
Percent Composition: C 56.62%, H 8.04%, N 5.08%, O 17.41%, Cl 12.86%
Properties: Crystallized as the monohydrate; changes crystalline form at 175°; dec 188-195°. [a]D20 -32.2° (c = 0.1 in water).
Optical Rotation: [a]D20 -32.2° (c = 0.1 in water)
 
Therap-Cat: Bronchodilator; tocolytic.
Keywords: ?Adrenergic Agonist; Bronchodilator; Ephedrine Derivatives; Tocolytic.