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CAS No 22254-24-6 , Ipratropium bromide

  • Name: Ipratropium bromide
  • Synonyms: [(1R,5S)-8-Methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate bromide;Ipratropium bromide;
  • CAS Registry Number:
  • Melting Point: 230-232 ºC
  • Safety Statements: S26
  • Hazard Symbols: Xn
  • EINECS: 244-873-8
  • Molecular Weight: 412.37
  • InChI: InChI=1/C20H30NO3.BrH/c1-14(2)21(3)16-9-10-17(21)12-18(11-16)24-20(23)19(13-22)15-7-5-4-6-8-15;/h4-8,14,16-19,22H,9-13H2,1-3H3;1H/q+1;/p-1/t16-,17?,18-,19?,21?;/m1./s1
  • Risk Statements: 20/22-36
  • Molecular Formula: C20H30BrNO3
  • Molecular Structure:CAS No:22254-24-6 Ipratropium bromide
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22254-24-6 Ipratropium bromide

  • IUPAC NAME-[8-methyl-8-(1-methylethyl)- 8-azoniabicyclo[3.2.1] oct-3-yl] 3-hydroxy-2-phenyl-propanoate MOLECULAR FORMULA-C20H30BrNO3 MOLAR MASS-412.37 g/mol
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641875
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22254-24-6 Ipratropium bromide

  • IUPAC NAME-[8-methyl-8-(1-methylethyl)- 8-azoniabicyclo[3.2.1] oct-3-yl] 3-hydroxy-2-phenyl-propanoate MOLECULAR FORMULA-C20H30BrNO3 MOLAR MASS-412.37 g/mol Ipratropium bromide is an anticholinergic drug used for the treatment of chronic obstructive ...
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641875
  • Address: Harsool Aurangabad,MaharashtraIndia

22254-24-6 Ipratropium bromide

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22254-24-6 Ipratropium bromide

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
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22254-24-6 IPRATROPIUM BROMIDE EP

  • United States Aceto Corp. [Manufacturer]
  • Tel: 516-627-6000
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  • Address: One Hollow Lane
    Lake Success, NY 11042-1215 ,United States
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22254-24-6 Ipratropium Bromide

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
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22254-24-6 IPRATROPIUM BROMIDE

  • Germany BIOTREND Chemikalien GmbH [Manufacturer]
  • Tel: ++49 (0)2 21 9 49 83 20
  • Fax: ++49 (0)2 21 9 49 83 25
  • Address: BIOTREND Chemikalien GmbH
    Eupener Str. 157
    D - 50933 Cologne
    Germany ,Germany
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22254-24-6 IPRATROPIUM BROMIDE

  • Switzerland BIOTREND Chemicals AG [Manufacturer]
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  • Fax: +41 44 805 76 77
  • Address: BIOTREND Chemicals AG
    Unterdorfstr. 21b
    CH-8602 Wangen/Zuerich
    Switzerland ,Switzerland
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22254-24-6 Ipratropium bromide

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22254-24-6 Ipratropium Bromide

  • India JAI RADHE SALES []
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. ,India
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References of Ipratropium bromide
Title: Ipratropium Bromide
CAS Registry Number: 22254-24-6
CAS Name: (3-endo,8-syn)-3-(3-Hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo[3.2.1]octane bromide
Synonyms: 3a-hydroxy-8-isopropyl-1aH,5aH-tropanium bromide (±)-tropate; 8-isopropylnoratropine methobromide; N-isopropylnoratropinium bromomethylate
Manufacturers' Codes: Sch-1000
Trademarks: Atem (Chiesi); Atrovent (Boehringer, Ing.); Bitrop (Boehringer, Ing.); Itrop (Boehringer, Ing.); Narilet (Boehringer, Ing.); Respontin (GSK); Rinatec (Boehringer, Ing.)
Molecular Formula: C20H30BrNO3
Molecular Weight: 412.36
Percent Composition: C 58.25%, H 7.33%, Br 19.38%, N 3.40%, O 11.64%
Literature References: Anticholinergic. Prepn: K. Zeile et al., ZA 6707766; eidem, US 3505337 (1968, 1970, both to Boehringer, Ing.); W. Schulz et al., Arzneim.-Forsch. 26, 960 (1976). Chemistry and pharmacokinetics: W. Deckers, Postgrad. Med. J. 51, Suppl. 7, 76 (1975). Pharmacology and toxicology: A. Engelhardt, H. Klupp, ibid. 82. Series of articles on pharmacology, toxicology, pharmacokinetics and clinical studies: Arzneim.-Forsch. 26, 974-985, 989-1020 (1976). Toxicity data: L. Sarafana et al., ibid. 985. Review: R. Bauer et al., in Pharmacological and Biochemical Properties of Drug Substances vol. 2, M. E. Goldberg, Ed. (Am. Pharm. Assoc., Washington, DC, 1979) pp 489-515. Symposium on pharmacology, toxicology and clinical efficacy: Am. J. Med. 81(5A), 1-102 (1986). Review of clinical toxicology: J. D. Truwit, Crit. Care Clin. 7, 639-657 (1991).
Properties: White crystals from n-propanol, mp 230-232°. Freely sol in water and lower alcohols. Insol in ether, chloroform and fluorohydrocarbons. Fairly stable in neutral and acid solns; rapidly hydrolyzed in alkaline soln. LD50 in male, female mice (mg/kg): 1001, 1083 orally; 12.29, 14.97 i.v.; 300, 340 s.c. LD50 in male, female rats (mg/kg): 1663, 1779 orally; 15.89, 15.70 i.v. (Sarafana).
Melting point: mp 230-232°
Toxicity data: LD50 in male, female mice (mg/kg): 1001, 1083 orally; 12.29, 14.97 i.v.; 300, 340 s.c.; LD50 in male, female rats (mg/kg): 1663, 1779 orally; 15.89, 15.70 i.v. (Sarafana)
Therap-Cat: Bronchodilator; antiarrhythmic.
Keywords: Antiarrhythmic; Antimuscarinic; Bronchodilator; Quaternary Ammonium Compounds.