Home > Name List By 1 > 1-[4, 4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl] piperidin-4-ol

CAS No 26864-56-2 , 1-[4,
4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]
piperidin-4-ol

  • Name: 1-[4,
    4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]
    piperidin-4-ol
  • Synonyms: R-16341; McN-JR-16,341; R 16341; Penfluridolum [INN-Latin];Semap; BRN 1558826; TLP-607;1-[4,
    4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]
    piperidin-4-ol; 26864-56-2; EINECS 248-074-5;
  • CAS Registry Number:
  • Transport: UN 2811
  • Melting Point: 105-107 ºC
  • Density: 1.29 g/cm3
  • Refractive index: 1.552
  • Water Solubility: H2O: insoluble
  • Safety Statements: R25
  • Hazard Symbols: T: Toxic;
  • EINECS: 248-074-5
  • Molecular Weight: 523.965096
  • InchiKey: MDLAAYDRRZXJIF-UHFFFAOYSA-N
  • InChI: InChI=1S/C28H27ClF5NO/c29-26-12-7-21(18-25(26)28(32,
    33)34)27(36)13-16-35(17-14-27)15-1-2-24(19-3-8-22(30)9-4-19)20-5-10-23
    (31)11-6-20/h3-12,18,24,36H,1-2,13-17H2
  • Risk Statements: S45
  • Molecular Formula: C28H27ClF5NO
  • Molecular Structure:CAS No:26864-56-2 1-[4,<br />4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]<br />piperidin-4-ol
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26864-56-2 Penfluridol

  • China Watson International Ltd. []
  • Tel: +86-(512)-55117610
  • Fax: +86-(512)-55117630
  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, ,China
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26864-56-2 Penfluridol

  • China Xilin Chemical Group Co., Ltd []
  • Tel: +86-(0)-15527136576
  • Fax: +86-(27)-83820093
  • Address: 16# Luojiashan, Wuchang District, Wuhan, Hubei 430071, ,China
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26864-56-2 Penfluridol

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
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26864-56-2 Penfluridol

  • Penfluridol
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,China
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26864-56-2 Penfluridol

  • Penfluridol, 99.0%Min
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,China
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26864-56-2 Penfluridol

  • Penfluridol, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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26864-56-2 Penfluridol

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China ,ZheJiangChina
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26864-56-2 Penfluridol

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26864-56-2 PENFLURIDOL

  • China HuaiBei SanHe Developing Co., Ltd. [Manufacturers]
  • Tel: 86-561-3191113
  • Fax: +86-561-3192253
  • Address: Room 201,Building ZY-1,GuCheng Road,Huaibei,Anhui,China ,anhuiChina
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26864-56-2 Penfluridol

  • China SHANGHAI HANHONG CHEMICAL,CO.,LTD. [Manufacturers]
  • Tel: +86-18917911573
  • Fax: +21 54291107
  • Address: Room 207,Zenghe Building ,Jiachuan Road 245, Xuhui District, Shanghai, China shang hai,shang haiChina
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References of 1-[4,
4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]
piperidin-4-ol
Title: Penfluridol
CAS Registry Number: 26864-56-2
CAS Name: 1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol
Synonyms: 1-[4,4-bis(p-fluorophenyl)butyl]-4-(4-chloro-a,a,a-trifluoro-m-tolyl)-4-piperidinol; 1-(4,4-bis(4-fluorophenyl)butyl)-4-hydroxy-4-(3-trifluoromethyl-4-chlorophenyl)piperidine
Manufacturers' Codes: R-16341
Trademarks: Semap (Janssen)
Molecular Formula: C28H27ClF5NO
Molecular Weight: 523.97
Percent Composition: C 64.18%, H 5.19%, Cl 6.77%, F 18.13%, N 2.67%, O 3.05%
Literature References: Prepn: H. K. F. Hermans, C. J. E. Niemegeers, DE 2040231; eidem, US 3575990 (both 1971 to Janssen); Sindelár et al., Collect. Czech. Chem. Commun. 38, 3879 (1973). Pharmacology and toxicology: Janssen et al., Eur. J. Pharmacol. 11, 139 (1970). Crystal structure: Koch, Acta Crystallogr. 29B, 1538 (1973).
Properties: White, microcrystals, mp 105-107°. Slightly sol in water, dil HCl (<0.5 mg/ml). LD50 orally in mice (day 7): 86.8 mg/kg (Janssen).
Melting point: mp 105-107°
Toxicity data: LD50 orally in mice (day 7): 86.8 mg/kg (Janssen)
Therap-Cat: Antipsychotic.
Keywords: Antipsychotic.