Home > Name List By n > N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2- hydroxy-2-methylpropanamide

CAS No 90357-06-5 , N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-
hydroxy-2-methylpropanamide

  • Name: N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-
    hydroxy-2-methylpropanamide
  • Synonyms: ICI 176334; Kalumid;N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-
    hydroxy-2-methylpropanamide; 90357-06-5; Calutide; Cosudex; ICI-176334;Casodex;
  • CAS Registry Number:
  • Transport: OTH
  • Melting Point: 191-193 ºC
  • Density: 1.52 g/cm3
  • Refractive index: 1.577
  • Water Solubility: Insoluble in water
  • Safety Statements: 26-36
  • Hazard Symbols: Xi: Irritant;
  • Molecular Weight: 430.373373
  • InchiKey: LKJPYSCBVHEWIU-UHFFFAOYSA-N
  • InChI: InChI=1S/C18H14F4N2O4S/c1-17(26,10-29(27,
    28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,
    26H,10H2,1H3,(H,24,25)
  • Risk Statements: 36/37/38
  • Molecular Formula: C18H14F4N2O4S
  • Molecular Structure:CAS No:90357-06-5 N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-<br />hydroxy-2-methylpropanamide
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90357-06-5 Bicalutamide merrypharms@yahoo.com

  • product Name Bicalutamide Synonyms Bicalutamide (Subject to patent free); 4-cyano-3-trifluoromethyl-N-(3-p-fluorophenylsulfonyl-2-hydroxy-2-methylpropionyl)aniline; N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hydroxy-2-methyl-p...
  • Min. Order: 1000
  • China Merry Pharmtech Co.,Ltd [Manufacturer, Trading Company]
  • Tel: 86-183-67150305
  • Fax: 86-183-67150305
  • Address: Linan Area hangzhou,ZhejiangChina
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90357-06-5 Bicalutamide

  • Bicalutamide 90357-06-5 Name: Bicalutamide 90357-06-5 Appearance:white powder Cas No:90357-06-5 EINECS:NA Formula:C18H14F4N2O4S Molecular Weight:430.37 Melting Point:191~193 °C Boiling Point: 575.4 °C Flash Point: 313.6 °C Usage:prostate cancer and h...
  • Min. Order: 1
  • FOB Price: USD600 - 800 /
  • China octagon chemicals limited [Manufacturer, Trading Company]
  • Tel: 86-571-28956650
  • Address: Room 5008, No.9 YanAn Road, Hangzhou, 310002, China Hangzhou,ZhejiangChina
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90357-06-5 Bicalutamide

  • China Chemrio International Limited [Manufacturer]
  • Tel: +86 574 2789 1268/ +86-139 5789 5864 (mobile)
  • Fax: +86 574 2789 1266
  • Address: Chemrio International Limited
    Room 611-612, Wante Business Center
    No.487 Yangmuqi Road,
    Hi-tech Park Ningbo, 315040,China null,nullChina
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90357-06-5 N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide

  • N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide
  • Germany chemcube UG [Manufacturer]
  • Tel: +49 (22 08) 7 75 04 06
  • Fax: +49 (22 08) 7 75 02 30 /
    +49 (32 12) 1 00 74 76
  • Address: chemcube UG
    Salierweg 1
    53859 Niederkassel
    Germany null,nullGermany
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90357-06-5 Bicalutamide

  • BicalutamideBicalutamide, 98%
  • China PMIDA AGROCHEMICAL CO.,LTD [Manufacturer]
  • Tel: +86-023-67030808-8010
  • Fax: +86-023-67030809
  • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone401121 ChongqingCHINA Chongqing,nullChina
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90357-06-5 Bicalutamide

  • Bicalutamide, 98%
  • China Shanghai Rainbow Chemistry Co., Ltd. [Manufacturer]
  • Tel: +86-21-64968086
  • Fax: +86-21-64968086
  • Address: Room 128, Building B, No. 8 Lane 1305, Huajing Road, Xuhui District, Shanghai, P.R. China 200000 Shanghai CHINA Shanghai,nullChina
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90357-06-5 Bicalutamide

  • United States HBCChem, Inc. [Manufacturers]
  • Tel: +1-510-219-6317
  • Fax: +1-510-675-0318
  • Address: null Union City,CaliforniaUnited States
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90357-06-5 Bicalutamide

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90357-06-5 Bicalutamide

  • Bicalutamide
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,nullChina
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90357-06-5 Bicalutamide

  • Bicalutamide4-cyano-3-trifluoromethyl-N-(3-p-fluorophenylsulfonyl-2-hydroxy-2-methylpropionyl)aniline, 99.0%Min
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,nullChina
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References of N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-
hydroxy-2-methylpropanamide
Title: Bicalutamide
CAS Registry Number: 90357-06-5
CAS Name: N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide
Synonyms: 4-cyano-3-trifluoromethyl-N-(3-p-fluorophenylsulfonyl-2-hydroxy-2-methylpropionyl)aniline; (±)-4¢-cyano-a,a,a-trifluoro-3-[(p-fluorophenyl)sulfonyl]-2-methyl-m-lactotoluidide
Manufacturers' Codes: ICI-176334
Trademarks: Casodex (AstraZeneca)
Molecular Formula: C18H14F4N2O4S
Molecular Weight: 430.37
Percent Composition: C 50.23%, H 3.28%, F 17.66%, N 6.51%, O 14.87%, S 7.45%
Literature References: Non-steroidal peripherally active antiandrogen. Prepn: H. Tucker, EP 100172; idem, US 4636505 (1984, 1987 both to ICI); and structure-activity: H. Tucker et al., J. Med. Chem. 31, 954 (1988). Resolution and activity of enantiomers: H. Tucker, G. J. Chesterson, ibid. 885. Pharmacokinetics: I. D. Cockshott et al., Eur. Urol. 18, Suppl. 3, 10 (1990). Clinical trials in prostate cancer: G. Lunglmayr, Horm. Res. 32, Suppl. 1, 77 (1989); D. W. W. Newling, Eur. Urol. 18 Suppl. 3, 18 (1990). Review of pharmacology: B. J. A. Furr in Hormonal Therapy of Prostatic Diseases: Basic and Clinical Aspects, M. Motta, M. Serio, Eds. (Mediocom Europe, Milan, 1987) 148-161.
Properties: Crystals from a 1:1 (v/v) mix of ethyl acetate and petroleum ether, mp 191-193°.
Melting point: mp 191-193°
Therap-Cat: Antiandrogen; antineoplastic (hormonal).
Keywords: Antiandrogen; Antineoplastic (Hormonal); Antiandrogens.