Home > Name List By n > N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2- methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamid...

CAS No 302962-49-8 , N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-
methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide

  • Name: N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-
    methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide
  • Synonyms: 302962-49-8; Spyrcel; BMS 354825; BMS354825; BMS-354825; Dasatinib [USAN];Sprycel; dasatinibum; Dasatinib anhydrous;N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-
    methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.408g/cm3
  • Flash Point: °C
  • Molecular Weight: 488.00554
  • InchiKey: ZBNZXTGUTAYRHI-UHFFFAOYSA-N
  • InChI: InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-
    17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,
    6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)
  • Molecular Formula: C22H26ClN7O2S
  • Molecular Structure:CAS No:302962-49-8 N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-<br />methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide
Search by region :

Select to

302962-49-8 Dasatinib anhydrous

  • Dasatinib anhydrous: DMF available Haorui, established in 1997, is a manufacturer and supplier of APIs, intermediates, veterinary and food additives. Our USFDA approved products Flumazenil, Granisetron HCl, Granisetron Base, Docetaxel Anhydrous, Irin...
  • China Haorui Industrial Dev.Co.,Ltd [Manufacturer, Trading Company]
  • Tel: 86-755-82960263
  • Fax: 86-755-82960262
  • Address: Rm.904-906,First Tower A,Yi Tian Rd,Futian District shenzhen,GuangdongChina
Contact Supplier

302962-49-8 Dasatinib

  • Name Dasatinib N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide Cas No. 302962-49-8 Formula C22H28ClN7O3S MW 488.01
  • China bolonpharm [Manufacturer]
  • Tel: 86-576-88702853
  • Fax: --
  • Address: Jiangkou Economic Development Zone,Huangyan, Taizhou, Zhejiang, China Taizhou,ZhejiangChina
Contact Supplier

302962-49-8 Dasatinib (BMS-354825)

  • As a potent and multi-targeted inhibitor, dasatinib (BMS-354825) can inhibit Abl, Src and c-Kit, with IC50 of <1 nM, 0.5 nM and 79 nM, respectively. More information please visit the website: http://www.creative-enzymes.com/product/Dasatinib-BMS35482...
  • Min. Order: 10
  • United States Creative Enzymes [Manufacturer]
  • Tel: 1-631-6197922
  • Fax: 1-631-9388127
  • Address: Shirley New York,New YorkUnited States
Contact Supplier

302962-49-8 Dasatinib

  • Dasatinib Dasatinib(BMS-354825) is a potent and dual Abl/ Src inhibitor IC50 of Target: Aurora Kinase Product Links: http://www.medchemexpress.cn/dasatinib.html Permanent link: http://www.medchemexpress.com/dasatinib.html
  • United States MedChemexpress LLC [Manufacturer]
  • Tel: 609-228-6898
  • Fax: --
  • Address: 18 Wilkinson Way, Princeton, NJ 08540, USA Princeton,New JerseyUnited States
Contact Supplier

302962-49-8 Dasatinib

  • Name Dasatinib N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide Cas No. 302962-49-8 Formula C22H28ClN7O3S MW 488.01
  • China Taizhou Bolon Pharmchem CO.,Ltd [Manufacturer]
  • Tel: 86-576-88702853
  • Address: Huangyan Jiangkou taizhou,ZhejiangChina
Contact Supplier

302962-49-8 DASATINIB HCL, 99%

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
Contact Supplier

302962-49-8 Dasatinib,302962-49-8

  • Product Name: Dasatinib Synonyms: Dasatinib(BMS-354825);BMS-354825;N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide;5-Thiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2...
  • China Taizhou Bolon Pharmachem Co.,Ltd./Bolon Pharm&Chem Co.,Ltd [Manufacturer, Trading Company]
  • Tel: 86-576-88702850
  • Fax: --
  • Address: Jiangkou Economic Development Zone,Huangyan, Taizhou, Zhejiang, China taizhou city,ZhejiangChina
Contact Supplier

302962-49-8 Dasatinib 302962-49-8

  • Product Name: Dasatinib Synonyms: Dasatinib(BMS-354825);BMS-354825;N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide;5-Thiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2...
  • China Taizhou Bolon Pharmachem Co.,Ltd./Bolon Pharm&Chem Co.,Ltd [Manufacturer, Trading Company]
  • Tel: 86-576-88702850
  • Fax: --
  • Address: Jiangkou Economic Development Zone,Huangyan, Taizhou, Zhejiang, China taizhou city,ZhejiangChina
Contact Supplier

302962-49-8 DASATINIB

  • Germany Cfm Oskar Tropitzsch [Manufacturer]
  • Tel: +49-9231-9619-0
  • Fax: +49-9231-9619-60
  • Address: Cfm Oskar Tropitzsch
    Waldershofer Str. 49-51
    95615 Marktredwitz
    Germany null,nullGermany
Contact Supplier

302962-49-8 DASATINIB

  • China Shanghai Jinglan Chemical Co., Ltd. [Manufacturer]
  • Tel: 86-21-37789410
  • Fax: 86-21-64966973
  • Address: Room 513, 5th Floor, Building B,
    No. 18, Lane 1305, Huajing Road,
    Shanghai, 200231, P.R. China null,nullChina
Contact Supplier

Select to

References of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-
methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide
Title: Dasatinib
CAS Registry Number: 302962-49-8
CAS Name: N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide
Manufacturers' Codes: BMS-354825
Molecular Formula: C22H26ClN7O2S
Molecular Weight: 488.01
Percent Composition: C 54.15%, H 5.37%, Cl 7.26%, N 20.09%, O 6.56%, S 6.57%
Literature References: Orally bioactive, ATP-competitive dual inhibitor of Src and Abl kinases. Prepn: J. Das et al., WO 0062778; eidem US 6596746 (2000, 2003 both to Bristol-Myers Squibb); and Src/Abl kinase inhibition study: L. J. Lombardo et al., J. Med. Chem. 47, 6658 (2004). In vivo evaluation vs imatinib-resistant mutants in chronic myeloid leukemia: N. P. Shah et al., Science 305, 399 (2004). Mechanism of action study: M. R. Burgess et al., Proc. Natl. Acad. Sci. USA 102, 3395 (2005). Review of therapeutic potential in chronic myeloid leukemia: T. O'Hare et al., Curr. Opin. Genet. Dev. 16, 92-99 (2006).
Properties: mp 279-280°.
Melting point: mp 279-280°
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Tyrosine Kinase Inhibitors.