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CAS No 30544-47-9 , 2-(2-hydroxyethoxy)ethyl 2-[3-(trifluoromethyl)anilino]benzoate

  • Name: 2-(2-hydroxyethoxy)ethyl 2-[3-(trifluoromethyl)anilino]benzoate
  • Synonyms: Etofenamato [INN-Spanish]; Etofenamatum [INN-Latin]; EINECS 250-231-8; Rheumon gel; Rheumon;Bayrogel; TVX 485; 30544-47-9;2-(2-hydroxyethoxy)ethyl 2-[3-(trifluoromethyl)anilino]benzoate;
  • CAS Registry Number:
  • Flash Point: 226.6°C
  • Boiling Point: 451.1°C at 760 mmHg
  • Density: 1.317g/cm3
  • Refractive index: 1.552
  • Safety Statements: Poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous routes. Experimental teratogenic and reproductive effects. Used as an anti-inflammatory agent. When heated to decomposition it emits very toxic fumes of F and NOx. See also FLUORIDES.
  • Flash Point: 226.6°C
  • EINECS: 250-231-8
  • Molecular Weight: 369.33503
  • InchiKey: XILVEPYQJIOVNB-UHFFFAOYSA-N
  • InChI: InChI=1S/C18H18F3NO4/c19-18(20,
    21)13-4-3-5-14(12-13)22-16-7-2-1-6-15(16)17(24)26-11-10-25-9-8-23/h1-7,
    12,22-23H,8-11H2
  • Molecular Formula: C18H18F3NO4
  • Molecular Structure:CAS No:30544-47-9 2-(2-hydroxyethoxy)ethyl 2-[3-(trifluoromethyl)anilino]benzoate
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30544-47-9 Etofenamate

  • Etofenamate, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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30544-47-9 Etofenamate

  • Etofenamate, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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30544-47-9 Etofenamate, 99%

  • Etofenamate, 99%
  • China Pleapharma Co.,Ltd [Manufacturer]
  • Tel: 86 23 67030808
  • Fax: 86 23 67030809
  • Address: 22F,Jingxin center,No.70 Xingguang Road,Yubei Zone,Chongqing402232 chongqingCHINA chongqing,China
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30544-47-9 Etofenamate

  • Etofenamate, 99%
  • China Tianjin Pharmacn Science Co., Ltd. [Manufacturer]
  • Tel: 86-22-23359620/ 86-13612042162 (mobile)
  • Fax: 86-22-23359620
  • Address: 1006 Sinochem Building, 707 Lianmeng RD, Shijiazhuang 050061, Hebei, China ,China
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30544-47-9 ETOFENAMATE

  • United States Carbomer, Inc. [Manufacturer]
  • Tel: 858-552-0992/ (800) 239-7129
  • Fax: 858-552-0999
  • Address: PO Box 261026-1026
    San Diego, CA 92196 ,United States
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30544-47-9 Etofenamate

  • Etofenamate
  • China Hallopharma [Manufacturer]
  • Tel: 0086-23-67030808
  • Fax: 0086-23-67030818
  • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone,401121 ChongqingCHINA Chongqing,China
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30544-47-9 Etofenamate

  • Etofenamate
  • China Inter-Chemical [Manufacturer]
  • Tel: 0086-23-67030808
  • Fax: 0086-23-67030818
  • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone,401121 ChongqingCHINA Chongqing,China
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30544-47-9 ETOFENAMATE

  • Germany Cfm Oskar Tropitzsch [Manufacturer]
  • Tel: +49-9231-9619-0
  • Fax: +49-9231-9619-60
  • Address: Cfm Oskar Tropitzsch
    Waldershofer Str. 49-51
    95615 Marktredwitz
    Germany ,Germany
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30544-47-9 Etofenamate

  • Etofenamate
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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30544-47-9 ETOFENAMATE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China ,China
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References of 2-(2-hydroxyethoxy)ethyl 2-[3-(trifluoromethyl)anilino]benzoate
Title: Etofenamate
CAS Registry Number: 30544-47-9
CAS Name: 2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid 2-(2-hydroxyethoxy)ethyl ester
Synonyms: N-(a,a,a-trifluoro-m-tolyl)anthranilic acid 2-(2-hydroxyethoxy)ethyl ester
Manufacturers' Codes: B-577; TV-485
Trademarks: Bayrogel (Bayropharm); Glasel (Troponwerke); Rheumon gel (Troponwerke; Bayer); Traumon Gel (Troponwerke)
Molecular Formula: C18H18F3NO4
Molecular Weight: 369.34
Percent Composition: C 58.53%, H 4.91%, F 15.43%, N 3.79%, O 17.33%
Literature References: Percutaneously active antiphlogistic agent. Prepn: K. H. Boltze et al., DE 1939112; eidem, US 3692818 (1971, 1972 both to Troponwerke). Series of articles on chemistry, analysis, biochemistry, pharmacology, toxicology, and clinical studies: Arzneim.-Forsch. 27, 1300-1363 (1977). Toxicity: H. Jacobi et al., ibid. 1333. Metabolism and GC determn: ibid. 31, 9-21 (1981).
Properties: Pale yellow viscous oil, thermolabile at 180°. bp.001 130-135°. uv max (methanol): 286 (E1%1cm 423). nD25 1.564. Sol in lower alcohols, ethyl acetate, acetone, chloroform, ether, benzene. Soly in water at 22°: 0.16 mg/100 ml. LD50 in male, female rats (mg/kg): 292, 470 orally; 140, 226 i.v.; 373, 397 i.p.; 643, 568 s.c. (Jacobi).
Boiling point: bp.001 130-135°
Index of refraction: nD25 1.564
Absorption maximum: uv max (methanol): 286 (E1%1cm 423)
Toxicity data: LD50 in male, female rats (mg/kg): 292, 470 orally; 140, 226 i.v.; 373, 397 i.p.; 643, 568 s.c. (Jacobi)
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal); Aminoarylcarboxylic Acid Derivatives.