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CAS No 30748-29-9 , 4-(3-methylbut-2-enyl)-1,2-diphenylpyrazolidine-3,5-dione

  • Name: 4-(3-methylbut-2-enyl)-1,2-diphenylpyrazolidine-3,5-dione
  • Synonyms: Methrazone;4-(3-methylbut-2-enyl)-1,2-diphenylpyrazolidine-3,5-dione; 30748-29-9; Phenylprenazone; Fenilprenazone; Feprazonum [INN-Latin]; Pheprazone;Prenazone; Analud;
  • CAS Registry Number:
  • Flash Point: 178.7°C
  • Boiling Point: 437.2°Cat760mmHg
  • Density: 1.174g/cm3
  • Refractive index: 1.599
  • Safety Statements: Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
  • Flash Point: 178.7°C
  • EINECS: 250-324-3
  • Molecular Weight: 320.385
  • InchiKey: RBBWCVQDXDFISW-UHFFFAOYSA-N
  • InChI: InChI=1S/C20H20N2O2/c1-15(2)13-14-18-19(23)21(16-9-5-3-6-10-16)22(20(18)
    24)17-11-7-4-8-12-17/h3-13,18H,14H2,1-2H3
  • Molecular Formula: C20H20N2O2
  • Molecular Structure:CAS No:30748-29-9 4-(3-methylbut-2-enyl)-1,2-diphenylpyrazolidine-3,5-dione
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30748-29-9 Feprazone

  • Feprazone
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,China
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30748-29-9 Verlukast

  • Verlukast, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
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  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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30748-29-9 Feprazone

  • Feprazone, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
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  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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30748-29-9 Feprazone

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30748-29-9 Feprazone

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30748-29-9 Feprazone, 99%

  • Feprazone, 99%
  • China Pleapharma Co.,Ltd [Manufacturer]
  • Tel: 86 23 67030808
  • Fax: 86 23 67030809
  • Address: 22F,Jingxin center,No.70 Xingguang Road,Yubei Zone,Chongqing402232 chongqingCHINA chongqing,China
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30748-29-9 Feprazone

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  • China Tianjin Pharmacn Science Co., Ltd. [Manufacturer]
  • Tel: 86-22-23359620/ 86-13612042162 (mobile)
  • Fax: 86-22-23359620
  • Address: 1006 Sinochem Building, 707 Lianmeng RD, Shijiazhuang 050061, Hebei, China ,China
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30748-29-9 Feprazone

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30748-29-9 Feprazone

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  • United States AvaChem Scientific LLC [Manufacturer]
  • Tel: 210-667-3815
  • Fax: 210-764-2240
  • Address: P.O.Box 78044278278 San Antonio, TexasUNITED STATES 78278 San Antonio, Texas,United States
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30748-29-9 Feprazone

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  • China Hallopharma [Manufacturer]
  • Tel: 0086-23-67030808
  • Fax: 0086-23-67030818
  • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone,401121 ChongqingCHINA Chongqing,China
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References of 4-(3-methylbut-2-enyl)-1,2-diphenylpyrazolidine-3,5-dione
Title: Feprazone
CAS Registry Number: 30748-29-9
CAS Name: 4-(3-Methyl-2-butenyl)-1,2-diphenyl-3,5-pyrazolidinedione
Synonyms: 4-prenyl-1,2-diphenyl-3,5-pyrazolidinedione; 4-prenyl-1,2-diphenyl-3,5-dioxopyrazolidine; 4-(b-isoamylenyl)-1,2-diphenyl-3,5-pyrazolidinedione; 4-(2-isopentenyl)-1,2-diphenyl-3,5-pyrazolidinedione; phenylprenazone; prenazone
Manufacturers' Codes: DA-2370
Trademarks: Analud (Unifa); Methrazone (Boehringer, Ing.); Zepelin (De Angeli)
Molecular Formula: C20H20N2O2
Molecular Weight: 320.39
Percent Composition: C 74.98%, H 6.29%, N 8.74%, O 9.99%
Literature References: Non-steroidal anti-inflammatory drug. Prepn: S. Casadio, G. Pala, DE 2031238; eidem, US 3703528 (1971, 1972 both to Ist. De Angeli); Casadio et al., Arzneim.-Forsch. 22, 171 (1972). Series of articles on physical-chemical data, pharmacology, toxicology and clinical studies: ibid. 174-281. Toxicity data: C. Bianchi, G. Bonardi, ibid. 196.
Properties: Fine, white odorless and tasteless crystalline powder, mp 156.5° (ethanol). Very sol in acetone, chloroform, DMF; sparingly sol in acetonitrile, benzene, 10% NaOH. Slightly sol in ether, methanol, ethanol, cyclohexane. Practically insol in 10% HCl, 10% acetic acid, water. uv max (ethanol): 246 nm (log e 4.19); (pH 9-12 buffer): 264 nm (log e 4.322-4.326). pKa 5.09 ± 0.07. LD50 in male mice, rats (mg/kg): 408.8, 386.4 i.p.; 1067, >2000 orally (Bianchi, Bonardi).
Melting point: mp 156.5° (ethanol)
pKa: pKa 5.09 ± 0.07
Absorption maximum: uv max (ethanol): 246 nm (log e 4.19); (pH 9-12 buffer): 264 nm (log e 4.322-4.326)
Toxicity data: LD50 in male mice, rats (mg/kg): 408.8, 386.4 i.p.; 1067, >2000 orally (Bianchi, Bonardi)
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal); Pyrazolones.