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CAS No 31362-50-2 , Bombesin

  • Name: Bombesin
  • Synonyms: 108: PN: US20090175821 PAGE: 403 claimedprotein;L-Methioninamide,5-oxo-L-prolyl-L-glutaminyl-L-arginyl-L-leucylglycyl-L-asparaginyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-L-leucyl-; 25: PN: WO2004075830 SEQID: 25 claimed protein; Bombesin 14;Alytesin,2-L-glutamine-6-L-asparagine- (8CI);Bombesin;
  • CAS Registry Number:
  • Density: 1.5g/cm3
  • Refractive index: 1.681
  • Water Solubility: 0.05 M acetic acid: 20 mg/mL, clear, colorless
  • Safety Statements: 22-24/25
  • Molecular Weight: 1619.8481
  • InchiKey: QXZBMSIDSOZZHK-UHFFFAOYSA-N
  • InChI: InChI=1S/C71H110N24O18S/c1-34(2)24-47(92-62(105)43(14-11-22-79-71(76)77)
    89-64(107)45(15-18-52(72)96)90-63(106)44-17-20-55(99)85-44)61(104)81-31-
    56(100)87-51(28-54(74)98)69(112)91-46(16-19-53(73)97)65(108)94-49(26-38-
    29-80-41-13-10-9-12-40(38)41)66(109)84-37(7)60(103)95-58(36(5)6)70(113)
    82-32-57(101)86-50(27-39-30-78-33-83-39)68(111)93-48(25-35(3)4)67(110)
    88-42(59(75)102)21-23-114-8/h9-10,12-13,29-30,33-37,42-51,58,80H,11,
    14-28,31-32H2,1-8H3,(H2,72,96)(H2,73,97)(H2,74,98)(H2,75,102)(H,78,
    83)(H,81,104)(H,82,113)(H,84,109)(H,85,99)(H,86,101)(H,87,100)(H,88,
    110)(H,89,107)(H,90,106)(H,91,112)(H,92,105)(H,93,111)(H,94,108)(H,95,
    103)(H4,76,77,79)
  • Molecular Formula: C71H110N24O18S
  • Molecular Structure:CAS No:31362-50-2 Bombesin
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31362-50-2 Bombesin

  • Bombesin
  • United Kingdom Fluorochem Ltd. [Importer/Exporter]
  • Tel: (01457) 868921 (4 lines)
  • Fax: (01457) 869360/860927
  • Address: Wesley Street, Old Glossop, Derbyshire SK13 7RY Old Glossop,DerbyshireUnited Kingdom
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31362-50-2 Bombesin

  • Bombesin
  • United States LKT Laboratories, Inc [Manufacturer]
  • Tel: (888)-558-5227
  • Fax:
  • Address: 2233 University Ave. West 55114-1600 St. PaulUNITED STATES 55114-1600 St. Paul,nullUnited States
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31362-50-2 BOMBESIN

  • Germany BIOTREND Chemikalien GmbH [Manufacturer]
  • Tel: ++49 (0)2 21 9 49 83 20
  • Fax: ++49 (0)2 21 9 49 83 25
  • Address: BIOTREND Chemikalien GmbH
    Eupener Str. 157
    D - 50933 Cologne
    Germany null,nullGermany
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31362-50-2 BOMBESIN

  • United States American Peptide Company, Inc. [Manufacturer]
  • Tel: 800-926-8272/ 408-733-7604
  • Fax: 888-670-0070
  • Address: Headquarters
    American Peptide Company, Inc.
    777 East Evelyn Ave
    Sunnyvale, CA 94086
    Tel: 800-926-8272; 408-733-7604
    Fax: 888-670-0070; 408-733-7603 null,nullUnited States
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31362-50-2 Bombesin

  • United States LKT Laboratories Inc. null
  • Tel: +1 888-558-5227
  • Fax: +1-(651)-644-8424
  • Address: Toll free 888-LKT-LABS St. Paul,nullUnited States
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31362-50-2 Bombesin

  • France NeoMPS SA [Manufacturers]
  • Tel: +33 (0)3 88 79 08 79
  • Fax: +33 (0)3 88 79 18 56
  • Address: 7 rue de Boulogne 67100 Strasbourg · France Strasbourg,StrasbourgFrance
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31362-50-2 Bombesin

  • China BAM BIOTECH CO., LTD. [Manufacturers]
  • Tel: 86-592-5592612
  • Fax: 86-592-
  • Address: 7/F Tower B No.268 Lianyi Building Heshan Road Xiamen CHINA Xiamen,fujianChina
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31362-50-2 BOMBESIN

  • United States Buckton Scott USA [Manufacturer]
  • Tel: 609 279 9609
  • Fax: 609 279 1909
  • Address: Buckton Scott USA
    330 North Harrison Street
    Princeton, NJ 08540 null,nullUnited States
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31362-50-2 Bombesin

  • Switzerland Biotrend Chemicals AG [Importer/Exporter]
  • Tel: +41-(44)-805 76 76
  • Fax: +41-(44)-805 76 77
  • Address: Unterdorfstr. 21b, Wangen/Zuerich CH-8602, Wangen/Zürich,nullSwitzerland
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31362-50-2 Bombesin

  • BombesinBombesin acetate hydrate, >97%
  • United States Promy Chemical, LLC [Manufacturer]
  • Tel: 5107581388
  • Fax: 5107589388
  • Address: 130 Travalini Ct94803 El SobranteUNITED STATES 94803 El Sobrante,nullUnited States
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References of Bombesin
Title: Bombesin
CAS Registry Number: 31362-50-2
CAS Name: 2-L-Glutamine-6-L-asparaginealytesin
Molecular Formula: C71H110N24O18S
Molecular Weight: 1619.85
Percent Composition: C 52.64%, H 6.84%, N 20.75%, O 17.78%, S 1.98%
Literature References: Pharmacologically active tetradecapeptide found in skins of European amphibians of the family Discoglossidae, principally Bombina bombina and Bombina variegata variegata. Isoln and structure: A. Anastasi et al., Experientia 27, 166 (1971). Pharmacological activity: V. Erspamer et al., J. Pharm. Pharmacol. 22, 875 (1970). Synthesis: L. Bernardi et al., Experientia 27, 873 (1971). It is a potent stimulant of gastric and pancreatic secretions in mammals; a bombesin-like immunoreactive peptide is found in both brain and gut, cf. J. M. Polak et al., Lancet 1, 1109 (1976). Other actions include hypertensive reactions, antidiuresis, and hyperglycemic activity. Bombesin has been shown to have a strong effect on core temperature lowering in rats: M. Brown et al., Science 196, 996 (1977). High levels of intracellular bombesin have also been found in human small-cell lung carcinoma: T. W. Moody et al., ibid. 214, 1246 (1981). Brief review of chemistry, isoln, purification: V. Mutt, Biochem. Soc. Trans. 8, 11 (1980). Effect on suppression of food intake: J. Gibbs et al., Nature 282, 208 (1979). Pharmacological reviews: G. Bertaccini, Pharmacol. Rev. 28, 127 (1976); S. R. Bloom, J. M. Polak, Adv. Clin. Chem. 21, 177 (1980).
 
Derivative Type: Hydrochloride
Molecular Formula: C71H112Cl2N24O18S
Molecular Weight: 1692.77
Percent Composition: C 50.38%, H 6.67%, Cl 4.19%, N 19.86%, O 17.01%, S 1.89%
Properties: Cryst from 99% ethanol, mp 185° (dec). [a]D24 -20.6° (c = 0.65 in DMF-HMPT 8:2).
Melting point: mp 185° (dec)
Optical Rotation: [a]D24 -20.6° (c = 0.65 in DMF-HMPT 8:2)