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CAS No 31362-50-2 , Bombesin

  • Name: Bombesin
  • Synonyms: 108: PN: US20090175821 PAGE: 403 claimedprotein;L-Methioninamide,5-oxo-L-prolyl-L-glutaminyl-L-arginyl-L-leucylglycyl-L-asparaginyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-L-leucyl-; 25: PN: WO2004075830 SEQID: 25 claimed protein; Bombesin 14;Alytesin,2-L-glutamine-6-L-asparagine- (8CI);Bombesin;
  • CAS Registry Number:
  • Density: 1.5g/cm3
  • Refractive index: 1.681
  • Water Solubility: 0.05 M acetic acid: 20 mg/mL, clear, colorless
  • Safety Statements: 22-24/25
  • Molecular Weight: 1619.8481
  • InchiKey: QXZBMSIDSOZZHK-UHFFFAOYSA-N
  • InChI: InChI=1S/C71H110N24O18S/c1-34(2)24-47(92-62(105)43(14-11-22-79-71(76)77)
    89-64(107)45(15-18-52(72)96)90-63(106)44-17-20-55(99)85-44)61(104)81-31-
    56(100)87-51(28-54(74)98)69(112)91-46(16-19-53(73)97)65(108)94-49(26-38-
    29-80-41-13-10-9-12-40(38)41)66(109)84-37(7)60(103)95-58(36(5)6)70(113)
    82-32-57(101)86-50(27-39-30-78-33-83-39)68(111)93-48(25-35(3)4)67(110)
    88-42(59(75)102)21-23-114-8/h9-10,12-13,29-30,33-37,42-51,58,80H,11,
    14-28,31-32H2,1-8H3,(H2,72,96)(H2,73,97)(H2,74,98)(H2,75,102)(H,78,
    83)(H,81,104)(H,82,113)(H,84,109)(H,85,99)(H,86,101)(H,87,100)(H,88,
    110)(H,89,107)(H,90,106)(H,91,112)(H,92,105)(H,93,111)(H,94,108)(H,95,
    103)(H4,76,77,79)
  • Molecular Formula: C71H110N24O18S
  • Molecular Structure:CAS No:31362-50-2 Bombesin
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31362-50-2 Bombesin

  • Bombesin
  • Germany chemcube UG [Manufacturer]
  • Tel: +49 (22 08) 7 75 04 06
  • Fax: +49 (22 08) 7 75 02 30 /
    +49 (32 12) 1 00 74 76
  • Address: chemcube UG
    Salierweg 1
    53859 Niederkassel
    Germany ,Germany
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31362-50-2 Bombesin

  • Bombesin
  • United States Chem-Impex International, Inc. [Manufacturer]
  • Tel: 630 766 2112
  • Fax: 630 766 2218
  • Address: 935 Dillon Drive Wood Dale IL 60191 USA ,United States
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31362-50-2 Bombesin

  • China GL Biochem (Shanghai) Ltd. [Distributor/Wholesaler]
  • Tel: +86-(21)-61263306
  • Fax: +86-(21)-61263300
  • Address: 519 Zi Yue Road, Shanghai, China 200241, ShangHai,ShangHaiChina
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31362-50-2 Bombesin

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31362-50-2 Bombesin

  • China China Langchem Inc. []
  • Tel: +86-(21)-58956006
  • Fax: +86-(21)-58956100
  • Address: 514 Room, 1# Building, 88# Cailun Road, Zhangjiang High Tech Park, Shanghai 201203, ,China
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31362-50-2 Bombesin

  • BombesinpGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
  • China Beijing HuameiHuli Biochem Ltd [Manufacturers]
  • Tel: 010-86181995
  • Fax: 010-86860610
  • Address: Beijing TongZhou District Beijing,BeijingChina
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31362-50-2 Bombesin

  • China GL Biochem (Shanghai) Co., Ltd. [Manufacturers]
  • Tel: +86-21-61263307
  • Fax: +86-21-61263399
  • Address: No.519,ZiYue Road,Zizhu Science Park,Minhang District,Shanghai,China Shanghai,ShanghaiChina
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31362-50-2 AG- 52226 BOMBESIN

  • United Kingdom AGTC Bioproducts Ltd [Manufacturer]
  • Tel: +44(0)1482646020
  • Fax: +44(0)1482646013
  • Address: AGTC Bioproducts Ltd
    Unit 4 Fleet Business Park, Hessle,
    ERY, HU13 9LX
    United Kingdom ,United Kingdom
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31362-50-2 Bombesin

  • Bombesin
  • France NeoMPS [Manufacturer]
  • Tel: + 33 3 88 79 87 04
  • Fax: + 33 3 88 79 18 56
  • Address: NeoMPS SA7 rue de Boulogne67100 StrasbourgFRANCE Strasbourg,France
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31362-50-2 BOMBESIN

  • Switzerland BIOTREND Chemicals AG [Manufacturer]
  • Tel: +41 44 805 76 76
  • Fax: +41 44 805 76 77
  • Address: BIOTREND Chemicals AG
    Unterdorfstr. 21b
    CH-8602 Wangen/Zuerich
    Switzerland ,Switzerland
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References of Bombesin
Title: Bombesin
CAS Registry Number: 31362-50-2
CAS Name: 2-L-Glutamine-6-L-asparaginealytesin
Molecular Formula: C71H110N24O18S
Molecular Weight: 1619.85
Percent Composition: C 52.64%, H 6.84%, N 20.75%, O 17.78%, S 1.98%
Literature References: Pharmacologically active tetradecapeptide found in skins of European amphibians of the family Discoglossidae, principally Bombina bombina and Bombina variegata variegata. Isoln and structure: A. Anastasi et al., Experientia 27, 166 (1971). Pharmacological activity: V. Erspamer et al., J. Pharm. Pharmacol. 22, 875 (1970). Synthesis: L. Bernardi et al., Experientia 27, 873 (1971). It is a potent stimulant of gastric and pancreatic secretions in mammals; a bombesin-like immunoreactive peptide is found in both brain and gut, cf. J. M. Polak et al., Lancet 1, 1109 (1976). Other actions include hypertensive reactions, antidiuresis, and hyperglycemic activity. Bombesin has been shown to have a strong effect on core temperature lowering in rats: M. Brown et al., Science 196, 996 (1977). High levels of intracellular bombesin have also been found in human small-cell lung carcinoma: T. W. Moody et al., ibid. 214, 1246 (1981). Brief review of chemistry, isoln, purification: V. Mutt, Biochem. Soc. Trans. 8, 11 (1980). Effect on suppression of food intake: J. Gibbs et al., Nature 282, 208 (1979). Pharmacological reviews: G. Bertaccini, Pharmacol. Rev. 28, 127 (1976); S. R. Bloom, J. M. Polak, Adv. Clin. Chem. 21, 177 (1980).
 
Derivative Type: Hydrochloride
Molecular Formula: C71H112Cl2N24O18S
Molecular Weight: 1692.77
Percent Composition: C 50.38%, H 6.67%, Cl 4.19%, N 19.86%, O 17.01%, S 1.89%
Properties: Cryst from 99% ethanol, mp 185° (dec). [a]D24 -20.6° (c = 0.65 in DMF-HMPT 8:2).
Melting point: mp 185° (dec)
Optical Rotation: [a]D24 -20.6° (c = 0.65 in DMF-HMPT 8:2)