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CAS No 356-12-7 , Fluocinonide

  • Name: Fluocinonide
  • Synonyms: Cortalar; Lidex;Fluocinonide; Topsymin; Vanos; Straderm; Metosyn;Fluocinolide; Biscosal; Bestasone;
  • CAS Registry Number:
  • Transport: UN 2811 6.1/PG 2
  • Melting Point: 309 ºC
  • Flash Point: 311.3°C
  • Boiling Point: 591.1°Cat760mmHg
  • Density: 1.34g/cm3
  • Refractive index: 1.56
  • Safety Statements: Poison by ingestion, subcutaneous, and intraperitoneal routes. Mutation data reported. Experimental reproductive effects. A steroid. When heated to decomposition it emits toxic fumes of F.
  • Hazard Symbols: T+: Very toxic;
  • Flash Point: 311.3°C
  • EINECS: 206-597-6
  • Molecular Weight: 494.524886
  • InchiKey: WJOHZNCJWYWUJD-IUGZLZTKSA-N
  • InChI: InChI=1S/C26H32F2O7/c1-13(29)33-12-20(32)26-21(34-22(2,
    3)35-26)10-15-16-9-18(27)17-8-14(30)6-7-23(17,4)25(16,28)19(31)11-24(15,
    26)5/h6-8,15-16,18-19,21,31H,9-12H2,1-5H3/t15-,16-,18-,19-,21+,23-,24-,
    25-,26+/m0/s1
  • Risk Statements: 28-63
  • Molecular Formula: C26H32F2O7
  • Molecular Structure:CAS No:356-12-7 Fluocinonide
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356-12-7 Fluocinonide

  • Fluocinonide Synonyms: 1,4-PREGNADIEN-6-ALPHA, 9-ALPHA-DIFLUORO-11-BETA, 16-ALPHA, 17,21-TETROL-3,20-DIONE 16,17-ACETONIDE 21-ACETATE;FLUOCINOLONE ACETONIDE 21-ACETATE;FLUOCINOMIDE;FLUOCINONIDE;FLUOCINONIDE ACETONIDE 21-ACETATE;droxy-,cyclic17-acetal...
  • Min. Order: 10000
  • FOB Price: USDfalse - false /
  • China Zhuhaishi Shuangbojie Technology Co.,Ltd. [Manufacturer]
  • Tel: 86-0756-8889897
  • Fax: 86-0756-8889806
  • Address: NO.101,Guofang Road,Gongbei,Zhuhai zhuhai,GuangdongChina
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356-12-7 Fluocinolone acetonide

  • Fluocinolone acetonide Another Name: (6-alpha,11-beta,16-alpha)-idene)bis(oxy)); (6alpha,11beta,16alpha)-idene)bis(oxy)); 20-dione,6,9-difluoro-11,12-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-,(6-alpha,11-bpregna-4-diene-3; 6-alpha,9-alpha-diflu...
  • Min. Order: 5200
  • FOB Price: USDfalse - false /
  • China Zhuzhou Hezhong Technology Development C [Manufacturer]
  • Tel: 86-0731-22290203
  • Address: No. 388, Huangshan Rd, Tianyuan District, Zhuzhou City, Hunan Province, P.R.China. zhuzhou,HunanChina
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356-12-7 Fluocinolone acetonide

  • Fluocinolone acetonide Another Name: (6-alpha,11-beta,16-alpha)-idene)bis(oxy)); (6alpha,11beta,16alpha)-idene)bis(oxy)); 20-dione,6,9-difluoro-11,12-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-,(6-alpha,11-bpregna-4-diene-3; 6-alpha,9-alpha-diflu...
  • Min. Order: 5200
  • FOB Price: USDfalse - false /
  • China Zhuzhou Hezhong Technology Development C [Manufacturer]
  • Tel: 86-0731-22290203
  • Address: No. 388, Huangshan Rd, Tianyuan District, Zhuzhou City, Hunan Province, P.R.China. zhuzhou,HunanChina
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356-12-7 Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-6,9-difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-,(6a,11b,16a)-

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356-12-7 A1578 FLUOCINONIDE

  • United Kingdom Carbosynth Limited [Manufacturer]
  • Tel: +44 (0)1635 578444
  • Fax: +44 (0)1635 579444
  • Address: Carbosynth Limited
    8&9 Old Station Business Park
    Compton
    Berkshire
    RG20 6NE
    UK ,United Kingdom
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356-12-7 Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-6,9-difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-,(6a,11b,16a)-

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
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356-12-7 Fluocinonide

  • Fluocinonide
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,China
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356-12-7 Fluocinonide

  • Fluocinonide, 99,00%
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,China
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356-12-7 Fluocinonide

  • Fluocinonide 356-12-7 B130510
  • China bepharm ltd. []
  • Tel: 86-21-51816456
  • Address: 128 Xiangyin Road, Room C320-321 Yangpu District, Shanghai 200433, China ,China
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356-12-7 Tyromedan

  • Tyromedan, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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References of Fluocinonide
Title: Fluocinonide
CAS Registry Number: 356-12-7
CAS Name: (6a,11b,16a)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
Synonyms: 6a,9-difluoro-11b,16a,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, cyclic 16,17-acetal with acetone, 21-acetate; 21-acetoxy-6a,9a-difluoro-11b-hydroxy-16a,17a-isopropylidenedioxy-1,4-pregnadiene-3,20-dione; 16a,17a-isopropylidene-6a-fluorotriamcinolone 21-acetate; fluocinolide (obsolete); fluocinolide acetate (obsolete); fluocinolone acetonide acetate
Trademarks: Biscosal (Ohta); Dermaplus (Ripari-Gero); Lidex (Syntex); Metosyn (Zeneca); Synalate (rescinded) (Syntex); Straderm (ITA); Topsym (Grñenthal); Topsymin (Grñenthal); Topsyne (Cassenne); Topsyn (Syntex)
Molecular Formula: C26H32F2O7
Molecular Weight: 494.52
Percent Composition: C 63.15%, H 6.52%, F 7.68%, O 22.65%
Literature References: Prepn: GB 916996 (1963 to Olin Mathieson), C.A. 59, 1716b (1963); H. J. Ringold, G. Rosenkranz, US 3124571; H. J. Ringold et al., US 3126375 (both 1964 to Syntex); J. Fried, US 3197469 (1965 to Pharm. Res. Prod.). NMR: A. D. Cross, P. W. Landis, J. Am. Chem. Soc. 86, 4005 (1964).
Properties: Crystals from methanol. mp 308-311°. [a]D +83° (chloroform). uv max: 237 nm (log e 4.18).
Melting point: mp 308-311°
Optical Rotation: [a]D +83° (chloroform)
Absorption maximum: uv max: 237 nm (log e 4.18)
Therap-Cat: Anti-inflammatory; glucocorticoid.
Keywords: Glucocorticoid.