Home > Name List By d > Dacarbazine

CAS No 4342-03-4 , Dacarbazine

  • Name: Dacarbazine
  • Synonyms: Dacarbazine;5-(3,3-Dimethyl-1-triazenyl)imidazole-4-carboxamide; 4-(3,3-Dimethyltriazeno)imidazole-5-carboxamide; 4-(Dimethyltriazeno)imidazole-5-carboxamide;
  • CAS Registry Number:
  • Melting Point: 199-205 ºC
  • Flash Point: 229.7 ºC
  • Boiling Point: 456.3 ºC at 760 mmHg
  • Density: 1.48 g/cm3
  • Refractive index: 1.678
  • Water Solubility: slightly soluble in ethanol and water
  • Safety Statements: R45;R46;R20/21/22;R36/37/38
  • Hazard Symbols: T: Toxic;
  • Flash Point: 229.7 ºC
  • EINECS: 224-396-1
  • Molecular Weight: 182.18
  • InChI: InChI=1/C6H10N6O/c1-12(2)11-10-6-4(5(7)13)8-3-9-6/h3H,1-2H3,(H2,7,13)(H,8,9)/b11-10+
  • Risk Statements: S53;S36/37/39;S45
  • Molecular Formula: C6H10N6O
  • Molecular Structure:CAS No:4342-03-4 Dacarbazine

Related products

Search by region :

Select to

4342-03-4 dacarbazine

Contact Supplier

4342-03-4 dacarbazine

  • China Beijing Lunarsun Pharmaceutical Co. Ltd. [Manufacturers]
  • Tel: 86-10-80771377
  • Fax: 86-10-80771338
  • Address: Building No.18 Yard No.11, Xisha Industrial Zone, Beiqijia Town, Changping District, Beijing, China Beijing,BeijingChina
Contact Supplier

4342-03-4 Deticene

Contact Supplier

4342-03-4 dacarbazine

  • Hong kong Keen Union International Limited [Manufacturers]
  • Tel: +86-(852)-21153613
  • Fax: +86-(852)-21153613
  • Address: 15/F., Highgrade Building, 117 Chatham Road, Tsimshatsui, Kowloon, Hongkong,HongkongHong kong
Contact Supplier

4342-03-4 Dacarbazine

  • Dacarbazine 5-(3,3-Dimethyl-1-triazenyl)imidazole-4-carboxamide, DTIC, DIC, NSC-45388 (Dimethyltriazeno)imidazolecarboxamide DACARBAZINE BP STANDARD DACARBAZINE RELATED COMPOUND A 5-AMINOIMIDAZOLE-4-CARBOXAMIDE HCL USP(CRM STANDARD) DACARBAZINE RELAT...
  • Russia Technology for Organic Synthesis Laboratory TOSLab [Manufacturers]
  • Tel: +7 (343) 3754135
  • Fax: +7 (343) 3754135
  • Address: Of. H-262, 28 Mira Str., PO Box 12 620002, Ekaterinburg, Russia Ekaterinburg,EkaterinburgRussia
Contact Supplier

4342-03-4 Dacarbazine

  • China Dalian Wista Pharmaceutical Co., Ltd null
  • Fax: 86-10-52577115
  • Address: No.16, Baimiao Industrial Park, Beiqijia Town, Changping District,102209, Beijing, P. R. China null,nullChina
Contact Supplier

4342-03-4 dacarbazine

Contact Supplier

4342-03-4 dacarbazine

Contact Supplier

4342-03-4 Dacarbazine

  • China Suzhou Leader Chemical Co., Ltd. [Manufacturers]
  • Tel: 0086-512-68412652 68412692
  • Fax: +86-512-68412653
  • Address: 6# Jinshan Road, New District, Suzhou Suzhou,jiangsuChina
Contact Supplier

4342-03-4 dacarbazine

Contact Supplier

Select to

6/8
Previous 1 2 3 4 5 6 7 8 Next
References of Dacarbazine
Title: Dacarbazine
CAS Registry Number: 4342-03-4
CAS Name: 5-(3,3-Dimethyl-1-triazenyl)-1H-imidazole-4-carboxamide
Synonyms: 5(or 4)-(dimethyltriazeno)imidazole-4(or 5)-carboxamide; DIC; DTIC
Manufacturers' Codes: NSC-45388
Trademarks: Dacatic (L×kefarmos); DTIC-Dome (Bayer); Deticene (Bellon)
Molecular Formula: C6H10N6O
Molecular Weight: 182.18
Percent Composition: C 39.56%, H 5.53%, N 46.13%, O 8.78%
Literature References: First synthesized in 1959 at the Southern Research Institute. Prepn: Shealy et al., J. Org. Chem. 27, 2150 (1962); Hano et al., Gann 59, 207 (1968), C.A. 69, 42527g (1968). Antitumor activity: Shealy et al., Biochem. Pharmacol. 11, 674 (1962); Hano et al., Gann 56, 417 (1965), C.A. 63, 18856g (1965). Mechanism of action studies: Saunders, Schultz, Biochem. Pharmacol. 19, 911 (1970). Metabolism: Skibba et al., ibid. 2043; Mizuno, Humphrey, Cancer Chemother. Rep. Part 1 56, 465 (1972). Review: Carter, Friedman, Eur. J. Cancer 8, 85-92 (1972), see also the series of articles on history, activity, mechanism of action and clinical studies: Cancer Treat. Rep. 60, 123-214 (1976).
Properties: Ivory microcrystalline substance; explosive decomp 250-255°. Also reported as mp 205°, Hano et al., loc. cit. (1965). uv max (0.1N HCl): 223 nm (7500); (pH 7): 237 nm (11200); both solns protected from light. Stable in neutral soln in absence of light.
Melting point: mp 205°, Hano et al., loc. cit. (1965)
Absorption maximum: uv max (0.1N HCl): 223 nm (7500); (pH 7): 237 nm (11200); both solns protected from light
CAUTION: This substance is reasonably anticipated to be a human carcinogen: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-76.
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Alkylating Agents.