Home > Name List By c > Cinchonidine

CAS No 485-71-2 , Cinchonidine

  • Name: Cinchonidine
  • Synonyms: alpha-Quinidine; 98%; L-Cinchonidine; alpha-Quinidine; (8alpha,9R)-Cinchonan-9-ol;4-Quinolyl-(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol;Cinchonidine;
  • CAS Registry Number:
  • Transport: 1544
  • Melting Point: 204-206 ºC
  • Density: 1.2 g/cm3
  • Refractive index: -107.5 ° (C=1, EtOH)
  • Alpha: -115 º (C=1, ETOH)
  • Safety Statements: R20/21/22
  • Hazard Symbols: Xn: Harmful;
  • HS Code: 29392900
  • EINECS: 207-622-3
  • Molecular Weight: 294.39
  • InChI: InChI=1/C19H22N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h2-7,9,13-14,18-19,22H,1,8,10-12H2
  • Risk Statements: S36/37
  • Molecular Formula: C19H22N2O
  • Molecular Structure:CAS No:485-71-2 Cinchonidine

Related products

Search by region :

Select to

485-71-2 Cinchonidine

  • India Biokemix [Importer/Exporter]
  • Tel: +91-(40)-6613 6366
  • Fax: +91-(40)-6683 6366
  • Address: Kanchan, 10, Umanagar, Begumpet, Hyderabad, Andhra Pradesh 500016, Manchester,nullIndia
Contact Supplier

485-71-2 (-)-CINCHONIDINE

  • China Shanghai SynCores Technologies Inc. [Manufacturer]
  • Tel: 86-21-51320499
  • Fax: 86-21-51320497
  • Address: Cailun road 538#,
    ZhangJiang Hi-Tech park,
    Pudong, Shanghai, P.R.China null,nullChina
Contact Supplier

485-71-2 Cinchonidine

  • China Xi'an app-chem bio(tech) co.,ltd [Manufacturers]
  • Tel: +86-29-88346300 029-88318908
  • Fax: +86-29-88346300
  • Address: Gazelle Valley,No.69,Jinye Road xi'an,shangxiChina
Contact Supplier

485-71-2 Cinchonidine

  • United States Norse Laboratories, Inc. [Importer/Exporter]
  • Tel: (805) 375-3113
  • Fax: 805 375 0812
  • Address: POB 976, Newbury Park, California (CA), 91319, USA Newbury Park,CaliforniaUnited States
Contact Supplier

485-71-2 Cinchonidine

Contact Supplier

485-71-2 CINCHONIDINE

  • India Alchem International Limited [Manufacturer]
  • Tel: +91 129 4266000
  • Fax: +91 129 2307192
  • Address: Alchem International Limited
    301, Avalon Apartments
    M.G. Road, Sultanpur
    New Delhi-110 030 null,nullIndia
Contact Supplier

485-71-2 Cinchonidine; 99%

  • Cinchonidine; 99%
  • Germany ABCR GmbH & Co KG [Manufacturer]
  • Tel: +49 721 95061-0
  • Fax: +49 721 95061-80
  • Address: Im Schlehert 10
    76187 Karlsruhe
    Germany null,nullGermany
Contact Supplier

485-71-2 Cinchonidine

  • Cinchonidine, 98+%
  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
Contact Supplier

Select to

4/4
Previous 1 2 3 4
References of Cinchonidine
Title: Cinchonidine
CAS Registry Number: 485-71-2
CAS Name: (8a,9R)-Cinchonan-9-ol
Synonyms: cinchovatine; a-quinidine
Molecular Formula: C19H22N2O
Molecular Weight: 294.39
Percent Composition: C 77.52%, H 7.53%, N 9.52%, O 5.43%
Literature References: Occurs in most varieties of cinchona bark, especially in bark of Cinchona pubescens Vahl. (C. succirubra Pav.) and C. pitayensis Wedd., Rubiaceae. Isoln: Leers, Ann. 82, 147 (1852). Structure: Rabe, ibid. 365, 359 (1909). Stereoisomeric with cinchonine: Koenigs, ibid. 347, 182 (1906). Configuration: Prelog, Zalán, Helv. Chim. Acta 27, 535 (1944); Prelog, H?fliger, ibid. 33, 2021 (1950); Roth, Pharmazie 16, 257 (1961); Lyle, Keefer, Tetrahedron 23, 3253 (1967). Biosynthetic studies: Battersby, Parry, Chem. Commun. 1971, 31. Toxicity studies: C. C. Johnson, C. F. Poe, Acta Pharmacol. Toxicol. 4, 265 (1948); E. W. Schafer, Jr. et al., Ecotoxicol. Environ. Saf. 6, 149 (1982).
Properties: Orthorhombic plates, prisms from alcohol, mp 210°. [a]D20 -109.2° (alc). uv absorption data: Kamath et al., Indian J. Chem. 6, 510 (1968). Sol in alcohol and chloroform; moderately sol in ether. Practically insol in water. pK1 5.80, pK2 10.03. Protect from light. LD50 i.p. in rats: 206 mg/kg (Johnson, Poe). LD50 orally in quail: >316 mg/kg (Schafer).
Melting point: mp 210°
pKa: pK1 5.80, pK2 10.03
Optical Rotation: [a]D20 -109.2° (alc)
Toxicity data: LD50 i.p. in rats: 206 mg/kg (Johnson, Poe); LD50 orally in quail: >316 mg/kg (Schafer)
 
Derivative Type: Dihydrochloride
Molecular Formula: C19H22N2O.2HCl
Molecular Weight: 367.31
Percent Composition: C 62.13%, H 6.59%, N 7.63%, O 4.36%, Cl 19.30%
Properties: White or slightly yellow crystals or powder. Freely sol in water or alcohol. Protect from light.
 
Derivative Type: Hydrochloride dihydrate
Molecular Formula: C19H22N2O.HCl.2H2O
Molecular Weight: 366.88
Percent Composition: C 62.20%, H 7.42%, N 7.64%, O 13.08%, Cl 9.66%
Properties: Cryst powder; loses all of its H2O at 120°. [a]D20 -117.5° (water). Sol in 25 parts cold water, more sol in boiling water; sol in alcohol, chloroform, slightly in ether. The aq soln is practically neutral. Protect from light.
Optical Rotation: [a]D20 -117.5° (water)
 
Derivative Type: Sulfate trihydrate
Molecular Formula: (C19H22N2O)2.H2SO4.3H2O
Molecular Weight: 740.91
Percent Composition: C 61.60%, H 7.07%, N 7.56%, O 19.43%, S 4.33%
Properties: Silky, acicular crystals; efflorescent on exposure to air and darkens in light. mp when anhydr ~240° with decompn. One gram dissolves in 70 ml water, 20 ml hot water, 90 ml alcohol, 40 ml hot alc, 620 ml chloroform. Practically insol in ether. The aq soln is practically neutral. Protect from light.
Melting point: mp when anhydr ~240° with decompn
 
Derivative Type: Epicinchonidine
CAS Registry Number: 550-54-9
CAS Name: (8a,9S)-Cinchonan-9-ol
Properties: mp 104°, [a]D20 +63° (c = 0.804 in alc): Rabe et al., Ann. 492, 253 (1932).
Melting point: mp 104°
Optical Rotation: [a]D20 +63° (c = 0.804 in alc): Rabe et al., Ann. 492, 253 (1932)
 
Therap-Cat: Antimalarial.
Keywords: Antimalarial.