Home > Name List By 3 > 3-(5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-11-ylidene)-N, N-dimethylpropan-1-amine

CAS No 50-48-6 , 3-(5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-11-ylidene)-N,
N-dimethylpropan-1-amine

  • Name: 3-(5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-11-ylidene)-N,
    N-dimethylpropan-1-amine
  • Synonyms: Flavyl; Seroten; Tryptanol; Damitriptyline; Proheptadiene; Lantron; Triptanol;3-(5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-11-ylidene)-N,
    N-dimethylpropan-1-amine; Elavil;Damilen;
  • CAS Registry Number:
  • Melting Point: 196-197 ºC
  • Flash Point: 174°C
  • Boiling Point: 398.2°Cat760mmHg
  • Density: 1.076g/cm3
  • Water Solubility: 9.7 MG/ML
  • Safety Statements: Human poison by an unspecified route. Poison experimentally by ingestion, intraperitoneal, subcutaneous, intramuscular, and intravenous routes. Human systemic effects by ingestion and intramuscular routes: changes in sleep, headache, paresthesia, convulsions, excitement, somnolence, muscle contractions, change in heart rate, and other cardiac changes. An experimental teratogen. Other experimental reproductive effects. An antidepressant. When heated to decomposition it emits toxic fumes of NOx.
  • Flash Point: 174°C
  • EINECS: 200-041-6
  • Molecular Weight: 277.40332
  • InchiKey: KRMDCWKBEZIMAB-UHFFFAOYSA-N
  • InChI: InChI=1S/C20H23N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-
    19(17)20/h3-6,8-12H,7,13-15H2,1-2H3
  • Molecular Formula: C20H23N
  • Molecular Structure:CAS No:50-48-6 3-(5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-11-ylidene)-N,<br />N-dimethylpropan-1-amine
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50-48-6 Amitriptyline

  • Catalog No.: FT-0653242 CAS No.: 50-48-6 NAME: Amitriptyline Synonyms: Elavil IUPAC Name: 3-(5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-11-ylidene)-N,N-dimethylpropan-1-amine InChI: InChI=1S/C20H23N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-...
  • China Finetech Industry Limited [Manufacturer]
  • Tel: 86-027-87465837
  • Address: Chukang Road,Wuhan, P.R.China (China Office) wuhan,HubeiChina
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50-48-6 1-Propanamine,3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-

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50-48-6 Amitriptyline hydrochloride

  • Amitriptyline hydrochloride
  • Hong kong Frapp's Pharma (Hongkong) Co.,Ltd [Manufacturer]
  • Tel: +852 8130 0917
  • Fax: +852 8130 0927
  • Address: Room 801,Mongkok Harbour Centre,638 Shanghai Street,Mongkok,Kowloon,Hongkang518001 MongkokHONG KONG Mongkok,Hong kong
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50-48-6 Amitriptyline HCl

  • Amitriptyline HCl
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,China
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50-48-6 Amitriptyline Hydrochloride

  • Amitriptyline Hydrochloride, 99.0%Min
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,China
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50-48-6 Amitriptyline

  • Amitriptyline, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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50-48-6 Amitriptyline Hydrocholoride

  • Amitriptyline Hydrocholoride, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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50-48-6 Amitriptyline

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
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50-48-6 1-Propanamine,3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-

  • United Kingdom Zerenex Molecular Limited [Manufacturers]
  • Tel: +44 (0) 1204 527 700
  • Fax: 44 (0) 1204 527700
  • Address: UNITED KINGDOM ,United Kingdom
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50-48-6 Amitriptyline hydrochloride

  • Amitriptyline hydrochloride, > 98%
  • Switzerland BIOTREND Chemicals AG [Manufacturer]
  • Tel: +41 44 805 76 76
  • Fax: +41 44 805 76 77
  • Address: BIOTREND Chemicals AG
    Unterdorfstr. 21b
    CH-8602 Wangen/Zuerich
    Switzerland ,Switzerland
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References of 3-(5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-11-ylidene)-N,
N-dimethylpropan-1-amine
Title: Amitriptyline
CAS Registry Number: 50-48-6
CAS Name: 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine
Synonyms: 10,11-dihydro-N,N-dimethyl-5H-dibenzo[a,d]cycloheptene-D5,g-propylamine; 5-(g-dimethylaminopropylidene)-5H-dibenzo[a,d]-10,11-dihydrocycloheptene; 10,11-dihydro-5-(g-dimethylaminopropylidene)-5H-dibenzo[a,d]cycloheptene; 5-(3-dimethylaminopropylidene)dibenzo[a,d][1,4]cycloheptadiene
Molecular Formula: C20H23N
Molecular Weight: 277.40
Percent Composition: C 86.59%, H 8.36%, N 5.05%
Literature References: Prepn: Hoffsommer et al., J. Org. Chem. 27, 4134 (1962); 28, 1751 (1963); J. Med. Chem. 8, 555 (1965); Engelhardt et al., BE 584061 (1960 to Merck & Co.); GB 858187; GB 858188 (both 1961 to Hoffmann-La Roche); Tristram, Tull, US 3205264 (1965 to Merck & Co.). Toxicity data: A. Tobe et al., Arzneim.-Forsch. 31, 1278 (1981). Comprehensive description: K. W. Blessel et al., Anal. Profiles Drug Subs. 3, 127-148 (1974).
 
Derivative Type: Hydrochloride
CAS Registry Number: 549-18-8
Manufacturers' Codes: Ro-4-1575
Trademarks: Adepril (Teofarma); Amineurin (Hexal); Domical (Berk); Elavil (AstraZeneca); Endep (Roche); Euplit (Desitin); Laroxyl (Roche); Lentizol (Lundbeck); Miketorin (Schering); Redomex (Lundbeck); Saroten (Bayer); Sarotex (Lundbeck); Triptizol (SIT); Tryptanol (Merck & Co.); Tryptizol (Merck & Co.)
Molecular Formula: C20H23N.HCl
Molecular Weight: 313.86
Percent Composition: C 76.54%, H 7.71%, N 4.46%, Cl 11.30%
Properties: Minute crystals, mp 196-197°. Freely sol in water, chloroform, alc. uv max (methanol): 240 nm (e 13800). pKa 9.4. LD50 in mice, rats (mg/kg): 350, 380 orally; 65, 75 i.p. (Tobe).
Melting point: mp 196-197°
pKa: pKa 9.4
Absorption maximum: uv max (methanol): 240 nm (e 13800)
Toxicity data: LD50 in mice, rats (mg/kg): 350, 380 orally; 65, 75 i.p. (Tobe)
 
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Tricyclics.