Home > Name List By p > Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxy-, (11b,16a)-

CAS No 51022-69-6 , Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxy-, (11b,16a)-

  • Name: Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxy-, (11b,16a)-
  • Synonyms: Cyclocort; CL 34699;Spiro[cyclopentane-1,8'-[2H]naphth[2',1':4,5]indeno[1,2-d][1,3]dioxole],pregna-1,4-diene-3,20-dione deriv.; Amcinonid;Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxy-, (11b,16a)-; Penticort; Amcinonide; Amciderm; Visderm;
  • CAS Registry Number:
  • Density: 1.33 g/cm3
  • Refractive index: 1.586
  • Water Solubility: Soluble in chloroform (200 mg/4.0 ml-clear, faint yellow solution)
  • Safety Statements: Poison by subcutaneous and intraperitoneal routes. A steroid. When heated to decomposition it emits toxic fumes of F−.
  • EINECS: 256-915-2
  • Molecular Weight: 502.63
  • InChI: InChI=1S/C28H35FO7/c1-16(30)34-15-22(33)28-23(35-26(36-28)9-4-5-10-26)13-20-19-7-6-17-12-18(31)8-11-24(17,2)27(19,29)21(32)14-25(20,28)3/h8,11-12,19-21,23,32H,4-7,9-10,13-15H2,1-3H3/t19?,20-,21-,23+,24?,25?,27-,28+/m0/s1
  • Molecular Formula: C28H35 F O7
  • Molecular Structure:CAS No:51022-69-6 Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxy-, (11b,16a)-

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References of Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxy-, (11b,16a)-
Title: Amcinonide
CAS Registry Number: 51022-69-6
CAS Name: (11b,16a)-21-(Acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxypregna-1,4-diene-3,20-dione
Synonyms: 9-fluoro-11b,16a,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with cyclopentanone 21-acetate
Manufacturers' Codes: CL-34699
Trademarks: Amciderm (Hermal); Cyclocort (Fujisawa); Penticort (Lederle)
Molecular Formula: C28H35FO7
Molecular Weight: 502.57
Percent Composition: C 66.92%, H 7.02%, F 3.78%, O 22.28%
Literature References: Prepn: W. Shultz et al., DE 2437847 (1975 to Am. Cyanamid), C.A. 83, 10608g (1975). Bioavailability study: R. Woodford, J. M. Haigh, Curr. Ther. Res. 26, 301 (1979). Therapeutic use in eczematoid conditions: G. L. Rocha et al., ibid. 19, 538 (1976); E. W. Rosenberg, Cutis 24, 642 (1979).
Therap-Cat: Glucocorticoid.
Keywords: Glucocorticoid.