Home > Name List By p > Pregna-1,4-diene-3,20-dione,6-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6a,11b,16a)-

CAS No 3385-03-3 , Pregna-1,4-diene-3,20-dione,6-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6a,11b,16a)-

  • Name: Pregna-1,4-diene-3,20-dione,6-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6a,11b,16a)-
  • Synonyms: Synaclyn; Nasarel; Aerospan; Syntaris;Pregna-1,4-diene-3,20-dione,6-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6a,11b,16a)-; Rhinalar; Bronalide; Lunis; Aerobid;Nasalide;
  • CAS Registry Number:
  • Flash Point: 305.7°C
  • Boiling Point: 581.8°Cat760mmHg
  • Density: 1.33g/cm3
  • Safety Statements: Human systemic effects by inhalation: deviated nasal septum, ulcerated nasal septum. An experimental teratogen. Experimental reproductive effects. A steroid. When heated to decomposition it emits toxic fumes of F−.
  • Flash Point: 305.7°C
  • EINECS: 222-193-2
  • Molecular Weight: 434.497743
  • InchiKey: XSFJVAJPIHIPKU-XWCQMRHXSA-N
  • InChI: InChI=1S/C24H31FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,
    3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h5-7,13-14,16-17,19-20,
    26,28H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1
  • Molecular Formula: C24H31FO6
  • Molecular Structure:CAS No:3385-03-3 Pregna-1,4-diene-3,20-dione,6-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6a,11b,16a)-
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3385-03-3 FLUNISOLIDE,USP26

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
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3385-03-3 flunisolide

  • IUPAC NAME-(1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one MOLECULAR FORMULA-C24H31FO6 MOLAR MASS-434.498 g/mol
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641875
  • Address: Plot No: 04, Mayur Park Road, Harsool Aurangabad,MaharashtraIndia

3385-03-3 Flunisolide

  • Flunisolide
  • Hong kong Frapp's Pharma (Hongkong) Co.,Ltd [Manufacturer]
  • Tel: +852 8130 0917
  • Fax: +852 8130 0927
  • Address: Room 801,Mongkok Harbour Centre,638 Shanghai Street,Mongkok,Kowloon,Hongkang518001 MongkokHONG KONG Mongkok,Hong kong
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3385-03-3 Flunisolide

  • Flunisolide, 99,00%
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,China
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3385-03-3 Flunisolide

  • Flunisolide, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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3385-03-3 Flunisolide

  • Flunisolide, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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3385-03-3 Flunisolide

  • China Ningbo Inno Pharmchem Co., Ltd. [Manufacturers]
  • Tel: +86-(574)-87319282
  • Fax: +86-(574)-56877908
  • Address: 5F, Building 4, 1035 Guangxian Rd., Ningbo Hi-Tech Park, Ningbo, Zhejiang 315040, Ningbo,ZhejiangChina
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3385-03-3 Flunisolide Anhydrous

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3385-03-3 FLUNISOLIDE 21-AL-IMPURITY

  • India VARDA Biotech (P) Ltd. [Manufacturer]
  • Tel: +91-22-6693 5686 / 2673 0141 / 2673 4258
  • Fax: +91-22-6693 5687
  • Address: 110 & 111, Kartik Complex
    New link Road, Andheri-(W)
    Mumbai-400053, INDIA. ,India
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3385-03-3 Flunisolide

  • United States Parchem Trading [Manufacturer]
  • Tel: 914.654.6800
  • Fax: 914.654.6899
  • Address: Parchem Trading Ltd.
    415 Huguenot Street
    New Rochelle, NY 10801 ,United States
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References of Pregna-1,4-diene-3,20-dione,6-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6a,11b,16a)-
Title: Flunisolide
CAS Registry Number: 3385-03-3
CAS Name: (6a,11b,16a)-6-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
Synonyms: 6a-fluoro-11b,16a,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone; 6a-fluoro-11b,21-dihydroxy-16a,17-isopropylidenedioxy-D1,4-pregnadiene-3,20-dione
Manufacturers' Codes: RS-3999
Trademarks: Aerobid (Forest); Bronalide (Syntex); Lunis (Valeas); Nasalide (Syntex); Rhinalar (Syntex); Synaclyn (Syntex); Syntaris (Syntex)
Molecular Formula: C24H31FO6
Molecular Weight: 434.50
Percent Composition: C 66.34%, H 7.19%, F 4.37%, O 22.09%
Literature References: Synthetic fluorinated corticosteroid related to prednisolone, q.v. Prepn using S. roseochromogenes: GB 933867 (1963 to Am. Cyanamid), C.A. 60, 3070f (1964). Prepn using Cunninghamella blakesleeana 8688b: H. J. Ringold, G. Rosenkranz, US 3124571; H. J. Ringold et al., US 3126375 (both 1964 to Syntex). Metabolism: N. I. Chu et al., Drug Metab. Dispos. 7, 81 (1979). Use in rhinitis: J. N. Sahay et al., Clin. Allergy 9, 17 (1979); J. K. Sarsfield, G. E. Thomson, Br. Med. J. 2, 95 (1979). Use in bronchial asthma: D. R. Webb et al., Ann. Allergy 42, 80 (1979). Clinical study in chronic asthma: R. G. Slavin et al., J. Allergy Clin. Immunol. 66, 379 (1980). Review of pharmacology and therapeutic efficacy: G. E. Pakes et al., Drugs 19, 397-411 (1980); of clinical studies with HFA formulation: S. Shafazand, G. Colice, Expert Opin. Pharmacother. 5, 1163-1173 (2004).
 
Derivative Type: 21-Acetate
CAS Registry Number: 4533-89-5
Manufacturers' Codes: RS-1320
Molecular Formula: C26H33FO7
Molecular Weight: 476.53
Percent Composition: C 65.53%, H 6.98%, F 3.99%, O 23.50%
 
Therap-Cat: Glucocorticoid; antiasthmatic.
Keywords: Antiallergic (Steroidal, Nasal); Antiasthmatic (Steroidal, Inhalant); Glucocorticoid.