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CAS No 543-21-5 , but-2-ynediamide

  • Name: but-2-ynediamide
  • Synonyms: Cellocidin; Acetylenedicarboxylic acid diamide; 2-Butynediamide; Aquamycin; ACETYLENEDICARBOXAMIDE;Lenamycin; Renamycin; Acetylene dicarboxamide;but-2-ynediamide;
  • CAS Registry Number:
  • Melting Point: 179 °C
  • Flash Point: 131.6°C
  • Boiling Point: 294°Cat760mmHg
  • Density: 1.41g/cm3
  • Safety Statements: Poison by ingestion and intravenous routes. Moderately toxic by skin contact. When heated to decomposition it emits toxic fumes of NOx. See also ACETYLENE COMPOUNDS and ALKYNES.
  • Hazard Symbols: T
  • Flash Point: 131.6°C
  • EINECS: 200-816-9
  • Molecular Weight: 112.08676
  • InchiKey: JBTGHKUTYAMZEZ-UHFFFAOYSA-N
  • InChI: InChI=1S/C4H4N2O2/c5-3(7)1-2-4(6)8/h(H2,5,7)(H2,6,8)
  • Risk Statements: 25-21
  • Molecular Formula: C4H4N2O2
  • Molecular Structure:CAS No:543-21-5 but-2-ynediamide
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543-21-5 ACETYLENEDICARBOXAMIDE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
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543-21-5 Acetylenedicarboxamide

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
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543-21-5 Acetylenedicarboxamide

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543-21-5 2-Butynediamide

  • China shanghai sphchem co.,ltd [Manufacturers]
  • Tel: +86-21-56491756 13512199871
  • Fax: 0
  • Address: NO.133, Wuye, Yangxin Road ,Shanghai China shanghai,shanghai ChinaChina
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543-21-5 Acetylenedicarboxamide

  • Germany Fox Chemicals GmbH [Manufacturer]
  • Tel: +49.7240.927151/ +49.160.95781845 (Mobile)
  • Fax: +49.7240.927150
  • Address: Fox Chemicals GmbH
    Bockstalstr.10 A
    D-76327 Pfinztal-Germany ,Germany
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543-21-5 Acetylenedicarboxamide

  • China Haihang Industry Co., Ltd. []
  • Tel: +86-(531)-88032799
  • Fax: +86-(531)-85821093
  • Address: 2/F, East Tower, Bldg 12, No. 2 Qilihe Road, Jinan 250100, ,China
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543-21-5 2-Butynediamide

  • China Maple Chemical Co.,ltd. [Manufacturer]
  • Tel: 86-574- 87512300
  • Fax: 86-574-82095182
  • Address: No.347,Sanbei Road,Sanbei Town,Cixi ,Zhejiang,China Ningbo,ZhejiangChina
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543-21-5 A08290 ACETYLENEDICARBOXAMIDE

  • United States Pfaltz & Bauer [Manufacturer]
  • Tel: (203) 574-0075
  • Fax: (203) 574-3181
  • Address: 172 E. Aurora St.
    Waterbury, CT 06708 ,United States
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543-21-5 ACETYLENEDICARBOXAMIDE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China ,China
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References of but-2-ynediamide
Title: Cellocidin
CAS Registry Number: 543-21-5
CAS Name: 2-Butynediamide
Synonyms: acetylenedicarboxamide; acetylenedicarboxylic acid diamide; aquamycin; lenamycin
Molecular Formula: C4H4N2O2
Molecular Weight: 112.09
Percent Composition: C 42.86%, H 3.60%, N 24.99%, O 28.55%
Line Formula: H2NCOCoCCONH2
Literature References: Antibiotic substance with antibacterial activity. Produced by Streptomyces chibaensis from soil collected at Chiba City, Japan: Suzuki et al., J. Antibiot. 11, 81 (1958). Synthesis from dimethyl acetylenedicarboxylate and concd ammonium hydroxide at -10°: Saggiomo, J. Org. Chem. 22, 1171 (1957); Suzuki, Okuma, J. Antibiot. 11, 84 (1958). Identity with lenamycin: Y. Sekizawa, Meiji Seika Kenkyu Nempo 1960, 42, C.A. 56, 14609a (1962). Biosynthesis: E. R. H. Jones, J. Chem. Soc. Perkin Trans. 1 1973, 148.
Properties: Crystals from dil methanol, dec. 216-218°. uv max (0.1N NaOH): 299 nm (E1%1cm 290). Sparingly sol in water, methanol, ethanol, acetone, chloroform, glacial acetic acid. Relatively stable in neutral or acid solns, showing no loss of activity at pH 2 to 7 when heated for 10 min at 100°. Unstable in alkaline soln evolving ammonia. LD50 i.v. in mice: 11 mg/kg (Suzuki).
Absorption maximum: uv max (0.1N NaOH): 299 nm (E1%1cm 290)
Toxicity data: LD50 i.v. in mice: 11 mg/kg (Suzuki)