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CAS No 58-85-5 , D-Biotin

  • Name: D-Biotin
  • Synonyms: Biotin; Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid;D-Biotin; D-Biotin pure; Vitamin B7;Vitamin H; Vitamin H (D-Biotin);
  • CAS Registry Number:
  • Transport: OTH
  • Melting Point: 231-233 ºC
  • Density: 1.267 g/cm3
  • Refractive index: 90.5 ° (C=2, 0.1mol/L NaOH)
  • Alpha: 89 º (C=1, 0.1N NAOH)
  • Safety Statements: S24/25
  • Hazard Symbols: Xn
  • HS Code: 29362930
  • EINECS: 200-399-3
  • Molecular Weight: 244.31
  • InChI: InChI=1/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)
  • Risk Statements: S24/25
  • Molecular Formula: C10H16N2O3S
  • Molecular Structure:CAS No:58-85-5 D-Biotin
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58-85-5 Biotin (Chemical Purity 97%) (Ring-6,6-D2, 98%)

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58-85-5 D-Biotin

  • D-Biotin Product name: D-Biotin Other name: Vitamin H; Biotin; Vitamin B7 CAS No.: 58-85-5 Assay: 98.5%~100.5% Packing: 1kg/tin M.F.: C10H16N2O3S M.W.: 244.3032 Appearance: White crystalline powder
  • China Hubei Yuancheng Pharmaceutical Co., Ltd [Manufacturer]
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58-85-5 D-Biotin

  • Synonyms: RONACARE(TM) BIOTIN PLUS;PHOTOPROBE(R) BIOTIN;VITAMIN B7;VITAMIN H;BIOTIN(V-H);BIOTINUM;BIOTIN, IMMOBILIZED ON DEXTRAN-LYSINE;BIOTIN, IMMOBILIZED ON DEXTRAN Product Details: Place of Origin: China Certification: ISO9001 Brand:YuanCheng Paym...
  • China Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd. [Manufacturer, Trading Company]
  • Tel: 86-731-22292056
  • Address: No. 388, Huangshan Rd, Tianyuan District, Zhuzhou City, Hunan Province, P.R.China. zhuzhou,HunanChina
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58-85-5 D-Biotin

  • Synonyms: RONACARE(TM) BIOTIN PLUS;PHOTOPROBE(R) BIOTIN;VITAMIN B7;VITAMIN H;BIOTIN(V-H);BIOTINUM;BIOTIN, IMMOBILIZED ON DEXTRAN-LYSINE;BIOTIN, IMMOBILIZED ON DEXTRAN Product Details: Place of Origin: China Certification: ISO9001 Brand:YuanCheng Paym...
  • China Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd. [Manufacturer, Trading Company]
  • Tel: 86-027-50756185
  • Fax: --
  • Address: No. 388, Huangshan Rd, Tianyuan District, Zhuzhou City, Hunan Province, P.R.China. Zhuzhou,HunanChina
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  • 58-85-5 D-Biotin Food grade Assay: 98.5%~100.5%

    • D-Biotin Food grade Assay: 98.5%~100.5% Product name: D-Biotin Other name: Vitamin H; Biotin; Vitamin B7 CAS No.: 58-85-5 Assay: 98.5%~100.5% Packing: 1kg/tin M.F.: C10H16N2O3S M.W.: 244.3032 Appearance: White crystalline powder Email: cx05 (at) yc...
    • China Wuhan Yuancheng Group [Manufacturer]
    • Tel: 86-027-50756063
    • Address: Zhongshan Road Wuchang Wuhan,HubeiChina
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    58-85-5 D-Biotin

    • D-Biotin Product details D-Biotin Product Name: D-Biotin Synonyms: D-Biotin; Biotin; Vitamin B7; Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid; Vitamin H (D-Biotin); D-Biotin pure; VH; Vitamin H CAS No: 58-85-5 Content: 99% Packing: 25kg...
    • China Wuhan Yuancheng Group [Manufacturer]
    • Tel: 86-027-50756063
    • Address: Zhongshan Road Wuchang Wuhan,HubeiChina
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    58-85-5 Vitamin B7

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    58-85-5 D-Biotin(Biotin) dahuamanager@whdhwy.com

    • High quality D-Biotin(Biotin) Synonyms:Biotin (8CI);(+)-Biotin;Biodermatin;Biaos II;Coenzyme R;Factor S(vitamin);Biotin CAS:58-85-5 Formula:C10H16N2O3S Molecular Weight:244.31 EINECS:200-399-3 Assay:99% Appearance:A White or off-white crystalline pow...
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    58-85-5 D-Biotin

    • Name: D-Biotin Synonyms: RONACARE(TM) BIOTIN PLUS;PHOTOPROBE(R) BIOTIN;VITAMIN B7;VITAMIN H;BIOTIN(V-H);BIOTINUM;BIOTIN, IMMOBILIZED ON DEXTRAN-LYSINE;BIOTIN, IMMOBILIZED ON DEXTRAN Product Details: Place of Origin: China Certification: ISO9001 Brand...
    • Min. Order: 25
    • FOB Price: USD1 - 1 /
    • China Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd. [Manufacturer]
    • Tel: 86-181-88938010
    • Address: No. 388, Huangshan Rd, Tianyuan District, Zhuzhou City, Hunan Province, P.R.China. Zhuzhou,HunanChina
    Contact Supplier

    58-85-5 D-Biotin

    • Name: D-Biotin Synonyms: RONACARE(TM) BIOTIN PLUS;PHOTOPROBE(R) BIOTIN;VITAMIN B7;VITAMIN H;BIOTIN(V-H);BIOTINUM;BIOTIN, IMMOBILIZED ON DEXTRAN-LYSINE;BIOTIN, IMMOBILIZED ON DEXTRAN Product Details: Place of Origin: China Certification: ISO9001 Brand...
    • Min. Order: 25
    • FOB Price: USD1 - 1 /
    • China Zhuzhou Yuancheng Hezhong Technology Development C [Manufacturer]
    • Tel: 86-027-50756060
    • Address: No. 388, Huangshan Rd, Tianyuan District, Zhuzhou City, Hunan Province, P.R.China. Zhuzhou,HunanChina
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    References of D-Biotin
    Title: Biotin
    CAS Registry Number: 58-85-5
    CAS Name: Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid
    Synonyms: cis-tetrahydro-2-oxothieno[3,4-d]imidazoline-4-valeric acid; cis-hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric acid; vitamin H; coenzyme R; bios II
    Trademarks: Biodermatin (Lafare)
    Molecular Formula: C10H16N2O3S
    Molecular Weight: 244.31
    Percent Composition: C 49.16%, H 6.60%, N 11.47%, O 19.65%, S 13.12%
    Literature References: Growth factor present in minute amounts in every living cell. Plays an indispensable role in numerous naturally occurring carboxylation reactions. Occurs mainly bound to proteins or polypeptides. The richest sources are liver, kidney, pancreas, yeast, and milk. The biotin content of cancerous tumors is higher than that of normal tissue. Biotin combines with the proteinaceous substance, avidin, in raw egg-white and becomes inactive. When on diets contg large amounts of raw egg-white the rat or chick develops characteristic skin lesions and growth is retarded; these symptoms can be prevented by feeding additional biotin. Isoln from egg yolk: K?gl, T?nnis, Z. Physiol. Chem. 242, 43 (1936); from liver: Gy?rgy et al., J. Biol. Chem. 131, 745 (1939); du Vigneaud et al., ibid. 140, 643 (1941). Identity of biotin with vitamin H: du Vigneaud et al., Science 92, 62 (1940). Structure: du Vigneaud et al., J. Biol. Chem. 146, 475 (1942). First synthesis: Harris et al., J. Am. Chem. Soc. 67, 2096 (1945). Configuration: Traub, Nature 178, 649 (1956). Stereospecific total synthesis of the naturally occurring d-form: P. N. Confalone et al., J. Am. Chem. Soc. 97, 5936 (1975); eidem, J. Org. Chem. 42, 1630 (1977); T. Ogawa et al., Carbohydr. Res. 57, C31 (1977); F. G. M. Vogel et al., Ann. 1980, 1972; R. R. Schmidt, M. Maier, Synthesis 1982, 747. Synthesis of the dl-form: P. N. Confalone et al., Helv. Chim. Acta 59, 1005 (1976); M. Marx et al., J. Am. Chem. Soc. 99, 6794 (1977); A. Fliri, K. Hohenlohe-Oehringen, Ber. 113, 607 (1980); Ph. Rossy et al., Tetrahedron Lett. 22, 3493 (1981). Biosynthetic studies: R. J. Parry, M. G. Kunitani, J. Am. Chem. Soc. 98, 4024 (1976); R. J. Parry, M. V. Naidu, Tetrahedron Lett. 1980, 4783. Coordination properties: H. Siegel, Experientia 37, 789 (1981). Mechanism of action: M. J. Cravey, H. Kohn, J. Am. Chem. Soc. 102, 3928 (1980); D. L. Vesely, Science 216, 1329 (1982). Reviews: A. F. Wagner, K. Folkers, Vitamins and Coenzymes (Wiley, New York, 1964) pp 138-159; Harris in The Vitamins vol. II, W. H. Sebrell, R. S. Harris, Eds. (Academic Press, New York, 2nd ed., 1968) pp 261-359; D. B. McCormick, Nutr. Rev. 33, 97-102 (1975). Review of assay methods: P. Gy?rgy, The Vitamins vol. VII, P. Gyorgy, W. N. Pearson, Eds. (1967) pp 303-313.
    Properties: Characteristics of biotin isolated from liver or milk (K?gl's b-biotin): fine long needles, mp 232-233°. [a]D21 +91° (c = 1 in 0.1N NaOH). Isoelec pt pH 3.5. pH of 0.01% aq soln 4.5. Soly at 25° (mg/100 ml): water ~22; 95% alc ~80. More sol in hot water and in dil alkali. Insol in other common organic solvents. The pure compd is stable to air and temp. Moderately acid and neutral solns are stable several months; alkaline solns are less stable, but appear reasonably stable up to a pH of about 9. Aq solns are very susceptible to mold growth. Acidic solns can be heat sterilized.
    Melting point: mp 232-233°
    Optical Rotation: [a]D21 +91° (c = 1 in 0.1N NaOH)
    Therap-Cat: Vitamin (enzyme cofactor).
    Therap-Cat-Vet: Vitamin (enzyme cofactor).
    Keywords: Vitamin/Vitamin Source.