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CAS No 58-85-5 , D-Biotin

  • Name: D-Biotin
  • Synonyms: Biotin; Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid;D-Biotin; D-Biotin pure; Vitamin B7;Vitamin H; Vitamin H (D-Biotin);
  • CAS Registry Number:
  • Transport: OTH
  • Melting Point: 231-233 ºC
  • Density: 1.267 g/cm3
  • Refractive index: 90.5 ° (C=2, 0.1mol/L NaOH)
  • Alpha: 89 º (C=1, 0.1N NAOH)
  • Safety Statements: S24/25
  • Hazard Symbols: Xn
  • HS Code: 29362930
  • EINECS: 200-399-3
  • Molecular Weight: 244.31
  • InChI: InChI=1/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)
  • Risk Statements: S24/25
  • Molecular Formula: C10H16N2O3S
  • Molecular Structure:CAS No:58-85-5 D-Biotin
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58-85-5 Biotine-D

  • Biotine-D
  • China Shanghai Synnad Chemical Co., Ltd. [Importer/Exporter]
  • Tel: 86 21 5109 7911
  • Fax: 86 21 5109 7955
  • Address: B-5 Ecust Science Park, No. 18, Lane 1305, Hua Jing Road, Shanghai 200231 China Shanghai,ShanghaiChina
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58-85-5 Vitamin B7

  • Vitamin B7
  • United States RIA International [Manufacturer]
  • Tel: 19735811282
  • Fax: 19735811283
  • Address: 11 Melanie Lane #17 East Hanover 07936 NJ UNITED STATES NJ,United States
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58-85-5 2-(trifluoromethyl)benzylsulfonyl chloride

  • 2-(trifluoromethyl)benzylsulfonyl chloride
  • China Shenzhen sailing chemical Co.,Ltd [Manufacturer]
  • Tel: 86-755-26415005
  • Fax: 86-755-26412646
  • Address: 1-403 Bei tou hao yuan Nanxing Road Nanshan District Shenzhen, Guangdong 518051 shenzhenCHINA shenzhen,China
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58-85-5 2-trifluoromethylbenzylsulfonyl chloride

  • 2-trifluoromethylbenzylsulfonyl chloride
  • China sales@credimate.com [Manufacturer]
  • Tel: +86 21 51872179
  • Fax: +86 21 51872179
  • Address: Room 2110, Tower 1, Changan Mansion, No. 1001 Changan Road200070 ShanghaiCHINA Shanghai,China
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58-85-5 D-BIOTIN

  • Germany Cfm Oskar Tropitzsch [Manufacturer]
  • Tel: +49-9231-9619-0
  • Fax: +49-9231-9619-60
  • Address: Cfm Oskar Tropitzsch
    Waldershofer Str. 49-51
    95615 Marktredwitz
    Germany ,Germany
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58-85-5 D-Biotin

  • D-Biotin, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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58-85-5 VITAMIN H(BIOTIN)(USP)

  • VITAMIN H(BIOTIN)(USP)Biotin
  • United States ChromaDex Inc. [Manufacturer]
  • Tel: 949-419-0288
  • Fax: 949-419-0294
  • Address: ChromaDex Inc.
    10005 Muirlands Blvd. Suite G - First Floor
    Irvine, CA 92618 ,United States
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58-85-5 Vitamin H

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China ,ZheJiangChina
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58-85-5 ETHYLPHENYLETHANOL

  • ETHYLPHENYLETHANOL
  • United States ChemSampCo Inc. [Manufacturer]
  • Tel: (609) 656-2440
  • Fax: (609) 656-2446
  • Address: ChemSampCo Inc.
    1880 Ryan Road
    Dallas, TX 75220 ,United States
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58-85-5 Biotin

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
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References of D-Biotin
Title: Biotin
CAS Registry Number: 58-85-5
CAS Name: Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid
Synonyms: cis-tetrahydro-2-oxothieno[3,4-d]imidazoline-4-valeric acid; cis-hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric acid; vitamin H; coenzyme R; bios II
Trademarks: Biodermatin (Lafare)
Molecular Formula: C10H16N2O3S
Molecular Weight: 244.31
Percent Composition: C 49.16%, H 6.60%, N 11.47%, O 19.65%, S 13.12%
Literature References: Growth factor present in minute amounts in every living cell. Plays an indispensable role in numerous naturally occurring carboxylation reactions. Occurs mainly bound to proteins or polypeptides. The richest sources are liver, kidney, pancreas, yeast, and milk. The biotin content of cancerous tumors is higher than that of normal tissue. Biotin combines with the proteinaceous substance, avidin, in raw egg-white and becomes inactive. When on diets contg large amounts of raw egg-white the rat or chick develops characteristic skin lesions and growth is retarded; these symptoms can be prevented by feeding additional biotin. Isoln from egg yolk: K?gl, T?nnis, Z. Physiol. Chem. 242, 43 (1936); from liver: Gy?rgy et al., J. Biol. Chem. 131, 745 (1939); du Vigneaud et al., ibid. 140, 643 (1941). Identity of biotin with vitamin H: du Vigneaud et al., Science 92, 62 (1940). Structure: du Vigneaud et al., J. Biol. Chem. 146, 475 (1942). First synthesis: Harris et al., J. Am. Chem. Soc. 67, 2096 (1945). Configuration: Traub, Nature 178, 649 (1956). Stereospecific total synthesis of the naturally occurring d-form: P. N. Confalone et al., J. Am. Chem. Soc. 97, 5936 (1975); eidem, J. Org. Chem. 42, 1630 (1977); T. Ogawa et al., Carbohydr. Res. 57, C31 (1977); F. G. M. Vogel et al., Ann. 1980, 1972; R. R. Schmidt, M. Maier, Synthesis 1982, 747. Synthesis of the dl-form: P. N. Confalone et al., Helv. Chim. Acta 59, 1005 (1976); M. Marx et al., J. Am. Chem. Soc. 99, 6794 (1977); A. Fliri, K. Hohenlohe-Oehringen, Ber. 113, 607 (1980); Ph. Rossy et al., Tetrahedron Lett. 22, 3493 (1981). Biosynthetic studies: R. J. Parry, M. G. Kunitani, J. Am. Chem. Soc. 98, 4024 (1976); R. J. Parry, M. V. Naidu, Tetrahedron Lett. 1980, 4783. Coordination properties: H. Siegel, Experientia 37, 789 (1981). Mechanism of action: M. J. Cravey, H. Kohn, J. Am. Chem. Soc. 102, 3928 (1980); D. L. Vesely, Science 216, 1329 (1982). Reviews: A. F. Wagner, K. Folkers, Vitamins and Coenzymes (Wiley, New York, 1964) pp 138-159; Harris in The Vitamins vol. II, W. H. Sebrell, R. S. Harris, Eds. (Academic Press, New York, 2nd ed., 1968) pp 261-359; D. B. McCormick, Nutr. Rev. 33, 97-102 (1975). Review of assay methods: P. Gy?rgy, The Vitamins vol. VII, P. Gyorgy, W. N. Pearson, Eds. (1967) pp 303-313.
Properties: Characteristics of biotin isolated from liver or milk (K?gl's b-biotin): fine long needles, mp 232-233°. [a]D21 +91° (c = 1 in 0.1N NaOH). Isoelec pt pH 3.5. pH of 0.01% aq soln 4.5. Soly at 25° (mg/100 ml): water ~22; 95% alc ~80. More sol in hot water and in dil alkali. Insol in other common organic solvents. The pure compd is stable to air and temp. Moderately acid and neutral solns are stable several months; alkaline solns are less stable, but appear reasonably stable up to a pH of about 9. Aq solns are very susceptible to mold growth. Acidic solns can be heat sterilized.
Melting point: mp 232-233°
Optical Rotation: [a]D21 +91° (c = 1 in 0.1N NaOH)
Therap-Cat: Vitamin (enzyme cofactor).
Therap-Cat-Vet: Vitamin (enzyme cofactor).
Keywords: Vitamin/Vitamin Source.