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CAS No 59277-89-3 , 2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one

  • Name: 2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one
  • Synonyms: Aciclovir; 59277-89-3;2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one; Zovirax; Avirax; Virorax;Acycloguanosine; Zovir; Vipral; Wellcome-248U;
  • CAS Registry Number:
  • Transport: OTH
  • Density: 1.77
  • Water Solubility: Water solubility: 0.7 mg/mL
  • Safety Statements: S22;S24/25;S36;S26
  • Hazard Symbols: Xi
  • EINECS: 261-685-1
  • Molecular Weight: 225.20464
  • InchiKey: MKUXAQIIEYXACX-UHFFFAOYSA-N
  • InChI: InChI=1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,
    1-2,4H2,(H3,9,11,12,15)
  • Risk Statements: 36/37/38
  • Molecular Formula: C8H11N5O3
  • Molecular Structure:CAS No:59277-89-3 2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one
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59277-89-3 Aciclovir

  • Aciclovir Alias: 2-amino-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-3H-purin-6-one CAS: 59277-89-3 EINECS: 261-685-1 MF: C8H11N5O3 MW: 225.2 MP: 256-257°C Appearance: White crystalline powders Email: cx05 (at) yccreate (dot) com Skype: annaaqq
  • Min. Order: 500
  • China Hubei Yuancheng Group [Manufacturer]
  • Tel: 86-027-50756063
  • Address: Zhongshan Road Wuhan,HubeiChina
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59277-89-3 Aciclovir

  • Aciclovir Alias: 2-amino-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-3H-purin-6-one CAS: 59277-89-3 EINECS: 261-685-1 MF: C8H11N5O3 MW: 225.2 MP: 256-257°C Appearance: White crystalline powders Any information ,Pls contact through spy@chembj.com Tel:86-0...
  • Min. Order: 3000
  • FOB Price: USDfalse - false /
  • China Wuhan Yuancheng Gongchuang Technology Co.Ltd. [Manufacturer]
  • Tel: 86-187-02759822
  • Fax: 86-27-68886696
  • Address: No.496,Zhongshan Road, Wuhan, Hubei, China Wuhan,HubeiChina
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59277-89-3 Aciclovir

  • Aciclovir Alias: 2-amino-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-3H-purin-6-one CAS: 59277-89-3 EINECS: 261-685-1 MF: C8H11N5O3 MW: 225.2 MP: 256-257°C Appearance: White crystalline powders EXW PRICE: USD37USD/KG samantha1@ycphar.com Skype:Oliver1989...
  • China Wuhan Yuancheng Gongchuang Technology Development Co.,Ltd. [Manufacturer, Trading Company]
  • Tel: 86-27-50756096
  • Fax: 86-27-68886696
  • Address: No.496,Zhongshan Road, Wuhan, Hubei, China Wuhan,HubeiChina
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  • 59277-89-3 high quality Aciclovir for sale

    • high quality Aciclovir for sale speciafictations: product name:Aciclovir CAS: 59277-89-3 EINECS: 261-685-1 Alias: 2-amino-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-3H-purin-6-one MF: C8H11N5O3 MW: 225.2 meating point: 256-257°C Appearance: White crysta...
    • FOB Price: USDfalse - false /
    • China Wuhan Yuancheng Gongchuang Technology Co.,ltd [Manufacturer]
    • Tel: 86-027-50756026
    • Address: No 496 Zhongshan Road wuahn,HubeiChina
    Contact Supplier

    59277-89-3 Aciclovir

    • Aciclovir Alias: 2-amino-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-3H-purin-6-one CAS: 59277-89-3 EINECS: 261-685-1 MF: C8H11N5O3 MW: 225.2 MP: 256-257°C Appearance: White crystalline powders EXW PRICE: USD37USD/KG
    • Min. Order: 3000
    • China Wuhan Yuancheng Saichuang Technology Co.Ltd [Manufacturer]
    • Tel: 86-027-50755972
    • Fax: --
    • Address: No.496, Zhongshan Road,Wuchang District wuhan,HubeiChina
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    59277-89-3 Acyclovir

    • Acyclovir, GMP, DMF Almitrine Bismesylate, DMF Amoxicillin sodium sterile, GMP,DMF Alpha- Keto to Isoleucine Calcium Salt, GMP,DMF Alpha- Keto to leucine Calcium Salt,GMP,DMF Alpha- Keto to Phenylalanine Calcium Salt,GMP,DMF Alpha- Keto to Valine Cal...
    • China Tess Pharmaceuticals Co., Ltd. [Trading Company]
    • Tel: 86-571-88357806
    • Address: ROOM1224,Heda Logistics Information Building No.2,Xiasha District, Hangzhou,ZhejiangChina
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    59277-89-3 Aciclovir

    • Alias: 2-amino-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-3H-purin-6-one CAS: 59277-89-3 EINECS: 261-685-1 MF: C8H11N5O3 MW: 225.2 MP: 256-257°C Appearance: White crystalline powders
    • Min. Order: 5000
    • China Hubei Yuancheng Saichuang Technology Co., Ltd. [Manufacturer, Trading Company]
    • Tel: 86-027-50756244
    • Fax: --
    • Address: 496# Zhongshan Road,Wuchang, Wuhan,Hubei,China wuhan ,HubeiChina
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    59277-89-3 Acyclovir

    • Acyclovir M.F: C8H11N5O3 CAS No: 59277-89-3 Appearance: white crystalline powder Content: 98.5% Grade: CP-2000, BP-98, USO-24 Use: Pharmaceuticals for herpes simplex virus meningitis and keratitis
    • China Wuhan Changland Technology Co.Ltd [Manufacturer]
    • Tel: 86-27-87290719
    • Fax: 86-27-68786490
    • Address: Changland Technology Co.,LTD Wuhan,HubeiChina
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    59277-89-3 acycloguanosine

    • China Taiyuan RHF CO., ltd. [Manufacturers]
    • Tel: 0351-7436719
    • Fax: +86-351-7436719
    • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
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    59277-89-3 acycloguanosine

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    References of 2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one
    Title: Acyclovir
    CAS Registry Number: 59277-89-3
    CAS Name: 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one
    Synonyms: acycloguanosine; 9-[(2-hydroxyethoxy)methyl]guanine
    Manufacturers' Codes: BW-248U; Wellcome 248U
    Trademarks: Acicloftal (Bruschettini); Avirase (Lampugnani); Cycloviran (Sigma-Tau); Maynar (Ferrer); Virmen (Menarini); Viruseen (Hommel); Zoliparin (Mann); Zovir (GSK); Zovirax (GSK)
    Molecular Formula: C8H11N5O3
    Molecular Weight: 225.20
    Percent Composition: C 42.67%, H 4.92%, N 31.10%, O 21.31%
    Literature References: Orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Prepn: H. J. Schaeffer, DE 2539963; idem, US 4199574 (1976, 1980 to Wellcome). Convenient synthesis from guanine: H. Matsumoto et al., Chem. Pharm. Bull. 36, 1153 (1988). Selectivity of action: G. B. Elion et al., Proc. Natl. Acad. Sci. USA 74, 5716 (1977). Chemistry, antiviral activity, metabolism: H. J. Schaeffer et al., Nature 272, 583 (1978). In vitro activity: P. Collins, D. J. Bauer, J. Antimicrob. Chemother. 5, 431 (1979). Effect on herpes simplex infections in mice: H. J. Field et al., Antimicrob. Agents Chemother. 15, 554 (1979); on herpes zoster in immunocompromised patients: H. H. Balfour et al., N. Engl. J. Med. 308, 1448 (1983). Treatment of primary episodes of genital herpes simplex infection: Y. J. Bryson et al., ibid. 916; of recurrent genital herpes: S. E. Straus et al., ibid. 310, 1545 (1984); J. M. Douglas et al., ibid. 1551. HPLC determn in serum and clinical pharmacokinetics: G. Bahrami et al., J. Chromatogr. B 816, 327 (2005). Symposia on pharmacology and clinical studies: Am. J. Med. 73, Suppl. 1A, 1-392 (1982); J. Antimicrob. Chemother. 12, Suppl. B, 1-202 (1983); Scand. J. Infect. Dis. Suppl. 47, 1-176 (1985). Review: R. J. Whitley, J. W. Gnann, Jr., N. Engl. J. Med. 327, 782-789 (1992).
    Properties: Crystals from methanol, mp 256.5-257°. LD50 in mice (mg/kg): >10,000 orally; 1000 i.p. (Schaeffer).
    Melting point: mp 256.5-257°
    Toxicity data: LD50 in mice (mg/kg): >10,000 orally; 1000 i.p. (Schaeffer)
    Therap-Cat: Antiviral.
    Keywords: Antiviral; Purines/Pyrimidinones.