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CAS No 61-90-5 , (2S)-2-amino-4-methylpentanoic acid

  • Name: (2S)-2-amino-4-methylpentanoic acid
  • Synonyms: L-leucine; (S)-Leucine; (S)-2-Amino-4-methylpentanoic acid; Leucinum; 61-90-5; leucine; (S)-2-Amino-4-methylvaleric acid; L-alpha-Aminoisocaproic acid;(2S)-2-amino-4-methylpentanoic acid;
  • CAS Registry Number:
  • Melting Point: 286-288 ºC
  • Density: 1,293 g/cm3
  • Alpha: 15.4 º (C=4, 6N HCL)
  • Water Solubility: 22.4 G/L (20 C)
  • Safety Statements: 24/25
  • EINECS: 200-522-0
  • Molecular Weight: 131.17292
  • InchiKey: ROHFNLRQFUQHCH-YFKPBYRVSA-N
  • InChI: InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
  • Risk Statements: S24/25
  • Molecular Formula: C6H13NO2
  • Molecular Structure:CAS No:61-90-5 (2S)-2-amino-4-methylpentanoic acid
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61-90-5 L-Leucine

  • United States Wintersun chemical [Manufacturers]
  • Tel: +1 909 930-1688 0086-574-87322704, 87298453, 27857
  • Fax: +1 909 947-1788
  • Address: Ontario,OntarioUnited States
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61-90-5 L-Leucine

  • China Sichuan Unibiochem Co., Ltd. [Manufacturers]
  • Tel: +86-28-85 09 35 35
  • Fax: +86-28-85096565
  • Address: No.16, Gaoshengqiao Road, Chengdu 610041, China Chengdu,SichuanChina
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61-90-5 L-Leucine

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61-90-5 LEUCINE BIOCHEMICA

  • Germany AppliChem GmbH [Manufacturer]
  • Tel: +49 6151 93 57 0
  • Fax: +49 6151 93 57 11
  • Address: AppliChem GmbH
    Ottoweg 4
    64291 Darmstadt
    Germany ,Germany
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61-90-5 L-Leucine

  • China Chemfar Ltd. []
  • Fax: 86-571-87859289
  • Address: 16E,Huarong Times Mansion, No.3880 Jiangnan Avenue, Binjiang District, Hangzhou, China ,China
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61-90-5 L-Leucine

  • China Shanghai GL Peptide Ltd [Manufacturers]
  • Tel: 86-21-61263381
  • Fax: 86-21-61263399
  • Address: 519 Ziyue Road, Minhang, Shanghai, China Shanghai,ShanghaiChina
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61-90-5 H-LEU-OH

  • United States Ivy Fine Chemicals [Manufacturer]
  • Tel: 856-465-8550
  • Fax: 856-616-1161
  • Address: Ivy Fine Chemicals
    1312 Bunker Hill Drive
    Cherry Hill, NJ 08003
    USA ,United States
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61-90-5 L-LEUCINE

  • United States Lab Express International Inc. [Manufacturer]
  • Tel: 973-227-1700/ 800-364-5291
  • Fax: 973-227-0023
  • Address: 10 Madison Road, Suite A,
    Fairfield, NJ 07004 ,United States
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61-90-5 L-Leucine

  • China A & Z Food Additives.Co.,Ltd [Importer/Exporter]
  • Tel: 0086 571 85126931
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  • Address: gucui road Hang zhou,Zhe JiangChina
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61-90-5 L-Leucine

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References of (2S)-2-amino-4-methylpentanoic acid
Title: Leucine
CAS Registry Number: 61-90-5
CAS Name: L-Leucine
Synonyms: Leu; L; 2-amino-4-methylvaleric acid; a-aminoisocaproic acid; (S)-2-amino-4-methylpentanoic acid
Molecular Formula: C6H13NO2
Molecular Weight: 131.17
Percent Composition: C 54.94%, H 9.99%, N 10.68%, O 24.39%
Literature References: An essential amino acid for human development. Discovery of leucine is attributed to Proust in 1819 who reported its separation from fermented milk curds. Early chemistry and biochemistry: Amino Acids and Proteins, D. M. Greenberg, Ed. (Charles C. Thomas, Springfield, IL, 1951) 950 pp., passim; J. P. Greenstein, M. Winitz, Chemistry of the Amino Acids vols 1-3 (John Wiley and Sons, Inc., New York, 1961) pp. 2075-2096, passim. Chromatographic determn of specific activity in biological fluids: E. P. Donahue et al., J. Chromatogr. 571, 29 (1991); separation of isotopes: P. Q. Baumann et al., ibid. 573, 11 (1992). Metabolism in humans: K. J. Motil et al., Metabolism 30, 783 (1981); in children receiving parenteral nutrition: O. Goulet et al., Am. J. Physiol. 265, E540 (1993). Kinetics modelling in humans: C. Cobelli et al., ibid. 261, E539 (1991).
Properties: White glistening hexagonal plates from aq alc. d18 1.293. Sublimes at 145-148°. Dec 293-295° (rapid heating, sealed tube). [M]D +21.0° (5N HCl); [M]D +29.5° (glacial acetic acid). [a]D25 -10.8° (c = 2.2); [a]D26 +15.1° in 6N HCl (38 mols HCl per mol leucine); [a]D20 +7.6° in 3N NaOH (30 mols NaOH per mol leucine). Rf value 0.79. Soly in water (g/l): 22.7 (0°); 24.26 (25°); 28.87 (50°); 38.23 (75°); 56.38 (100°); in 99% alcohol: 0.72; in acetic acid: 10.9. Insol in ether.
Optical Rotation: [a]D25 -10.8° (c = 2.2); [a]D26 +15.1° in 6N HCl (38 mols HCl per mol leucine); [a]D20 +7.6° in 3N NaOH (30 mols NaOH per mol leucine)
Density: d18 1.293
 
Derivative Type: DL-Form
Properties: Leaflets fom water. Sweet taste. Dec 332° (also reported as 290°). Sublimes. pK1 2.36; pK2 9.60. Soly in water (g/l): 7.97 (0°); 9.91 (25°); 14.06 (50°); 22.76 (75°); 42.06 (100°); in 90% alcohol: 1.3. Insol in ether.
pKa: pK1 2.36; pK2 9.60
 
Derivative Type: Hydrochloride
Molecular Formula: C6H13NO2.HCl
Molecular Weight: 167.63
Percent Composition: C 42.99%, H 8.42%, N 8.36%, O 19.09%, Cl 21.15%
Properties: Crystals. Freely sol in water.
 
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