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CAS No 61-90-5 , (2S)-2-amino-4-methylpentanoic acid

  • Name: (2S)-2-amino-4-methylpentanoic acid
  • Synonyms: L-leucine; (S)-Leucine; (S)-2-Amino-4-methylpentanoic acid; Leucinum; 61-90-5; leucine; (S)-2-Amino-4-methylvaleric acid; L-alpha-Aminoisocaproic acid;(2S)-2-amino-4-methylpentanoic acid;
  • CAS Registry Number:
  • Melting Point: 286-288 ºC
  • Density: 1,293 g/cm3
  • Alpha: 15.4 º (C=4, 6N HCL)
  • Water Solubility: 22.4 G/L (20 C)
  • Safety Statements: 24/25
  • EINECS: 200-522-0
  • Molecular Weight: 131.17292
  • InchiKey: ROHFNLRQFUQHCH-YFKPBYRVSA-N
  • InChI: InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
  • Risk Statements: S24/25
  • Molecular Formula: C6H13NO2
  • Molecular Structure:CAS No:61-90-5 (2S)-2-amino-4-methylpentanoic acid
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61-90-5 LEUCINE, L-(P)

  • United States ChromaDex Inc. [Manufacturer]
  • Tel: 949-419-0288
  • Fax: 949-419-0294
  • Address: ChromaDex Inc.
    10005 Muirlands Blvd. Suite G - First Floor
    Irvine, CA 92618 ,United States
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61-90-5 L-Leucine

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61-90-5 L-Leucine

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61-90-5 L-LEUCINE, USP GRADE

  • United States Research Organics, Inc. [Manufacturer]
  • Tel: 216-883-8025/ 800-321-0570
  • Fax: 216-883-1576
  • Address: 4353 East 49th Street
    Cleveland, OH 44125 ,United States
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61-90-5 L-LEUCINE

  • United States Seidler Chemical Company [Manufacturer]
  • Tel: (973) 465-1122
  • Fax: (973) 465-4469
  • Address: 537 Raymond Blvd.
    Newark, NJ 07105 ,United States
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61-90-5 L-Leucine

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61-90-5 08053 H-LEU-OH L-LEUCINE

  • Switzerland Senn Chemicals AG [Manufacturer]
  • Tel: +41 (0)43 422 2400
  • Fax: +41 (0)43 422 2424
  • Address: Senn Chemicals AG
    P.O. Box 267
    Guido Senn Strasse 1, CH-8157 Dielsdorf
    Switzerland ,Switzerland
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61-90-5 L-LEUCINE

  • China YANGZHOU CHEMICAL CO.,LTD. [Manufacturers]
  • Tel: 86-514-87864167
  • Fax: +86-514-87859301,87859302,87859303
  • Address: 7/F,18 WEST WENCHANG ROAD,YANGZHOU,JIANGSU,CHINA yangzhou,jiangsuChina
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61-90-5 Leucine (L-Leucine)

  • Switzerland Senn Chemicals AG [Other]
  • Tel: +41-(43)-422-2400
  • Fax: +41-(43)-422-2424
  • Address: Industriestrasse 12, Dielsdorf CH-8157, Dielsdorf,Switzerland
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61-90-5 L-Leucine

  • China TRITON CHEMTECH CO., LTD. []
  • Fax: +86-21-58895894
  • Address: Room 717, 7/F, Information Tower, 1403 Minsheng Road, Shanghai, 200135, China ,China
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References of (2S)-2-amino-4-methylpentanoic acid
Title: Leucine
CAS Registry Number: 61-90-5
CAS Name: L-Leucine
Synonyms: Leu; L; 2-amino-4-methylvaleric acid; a-aminoisocaproic acid; (S)-2-amino-4-methylpentanoic acid
Molecular Formula: C6H13NO2
Molecular Weight: 131.17
Percent Composition: C 54.94%, H 9.99%, N 10.68%, O 24.39%
Literature References: An essential amino acid for human development. Discovery of leucine is attributed to Proust in 1819 who reported its separation from fermented milk curds. Early chemistry and biochemistry: Amino Acids and Proteins, D. M. Greenberg, Ed. (Charles C. Thomas, Springfield, IL, 1951) 950 pp., passim; J. P. Greenstein, M. Winitz, Chemistry of the Amino Acids vols 1-3 (John Wiley and Sons, Inc., New York, 1961) pp. 2075-2096, passim. Chromatographic determn of specific activity in biological fluids: E. P. Donahue et al., J. Chromatogr. 571, 29 (1991); separation of isotopes: P. Q. Baumann et al., ibid. 573, 11 (1992). Metabolism in humans: K. J. Motil et al., Metabolism 30, 783 (1981); in children receiving parenteral nutrition: O. Goulet et al., Am. J. Physiol. 265, E540 (1993). Kinetics modelling in humans: C. Cobelli et al., ibid. 261, E539 (1991).
Properties: White glistening hexagonal plates from aq alc. d18 1.293. Sublimes at 145-148°. Dec 293-295° (rapid heating, sealed tube). [M]D +21.0° (5N HCl); [M]D +29.5° (glacial acetic acid). [a]D25 -10.8° (c = 2.2); [a]D26 +15.1° in 6N HCl (38 mols HCl per mol leucine); [a]D20 +7.6° in 3N NaOH (30 mols NaOH per mol leucine). Rf value 0.79. Soly in water (g/l): 22.7 (0°); 24.26 (25°); 28.87 (50°); 38.23 (75°); 56.38 (100°); in 99% alcohol: 0.72; in acetic acid: 10.9. Insol in ether.
Optical Rotation: [a]D25 -10.8° (c = 2.2); [a]D26 +15.1° in 6N HCl (38 mols HCl per mol leucine); [a]D20 +7.6° in 3N NaOH (30 mols NaOH per mol leucine)
Density: d18 1.293
 
Derivative Type: DL-Form
Properties: Leaflets fom water. Sweet taste. Dec 332° (also reported as 290°). Sublimes. pK1 2.36; pK2 9.60. Soly in water (g/l): 7.97 (0°); 9.91 (25°); 14.06 (50°); 22.76 (75°); 42.06 (100°); in 90% alcohol: 1.3. Insol in ether.
pKa: pK1 2.36; pK2 9.60
 
Derivative Type: Hydrochloride
Molecular Formula: C6H13NO2.HCl
Molecular Weight: 167.63
Percent Composition: C 42.99%, H 8.42%, N 8.36%, O 19.09%, Cl 21.15%
Properties: Crystals. Freely sol in water.
 
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