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CAS No 6493-05-6 , 3,7-dimethyl-1-(5-oxohexyl)purine-2,6-dione

  • Name: 3,7-dimethyl-1-(5-oxohexyl)purine-2,6-dione
  • Synonyms: Pentoxyfylline; Pentoxil; Pentoxifyllin;3,7-dimethyl-1-(5-oxohexyl)purine-2,6-dione; Vazofirin;Trental; Pentoxyphylline; Pentoxiphyllium; Oxpentifylline; Torental;
  • CAS Registry Number:
  • Flash Point: 275.1°C
  • Boiling Point: 531.3°Cat760mmHg
  • Density: 1.31g/cm3
  • Safety Statements: Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. Human systemic effects by ingestion: pulse rate decrease with fall in blood pressure. Human mutation data reported. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
  • Hazard Symbols: Xn
  • Flash Point: 275.1°C
  • EINECS: 229-374-5
  • Molecular Weight: 278.30702
  • InchiKey: BYPFEZZEUUWMEJ-UHFFFAOYSA-N
  • InChI: InChI=1S/C13H18N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13
    (17)20/h8H,4-7H2,1-3H3
  • Risk Statements: 22
  • Molecular Formula: C13H18N4O3
  • Molecular Structure:CAS No:6493-05-6 3,7-dimethyl-1-(5-oxohexyl)purine-2,6-dione
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6493-05-6 Pentoxifylline

  • Pentoxifylline 98 purity 6493-05-6 Pentoxifylline 98 purity 6493-05-6
  • China bolonpharm [Manufacturer]
  • Tel: 86-576-88702853
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  • Address: Jiangkou Economic Development Zone,Huangyan, Taizhou, Zhejiang, China Taizhou,ZhejiangChina
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6493-05-6 Pentoxifylline 6493-05-6

  • Product Name: Pentoxifylline Tag: Trental,Pentoxifylline,Pentox, Pentoxil and Flexital 1. Basic Information: Product Name Pentoxifylline Synonym Trental,3,7-Dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione CAS 6493-05-6 MF C13H18N4O3 MW 278.31...
  • China Saichuang Far Into the Company [Manufacturer]
  • Tel: 86-027-50756254
  • Address: Zhongshanlu No.497 wuhan,HubeiChina
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6493-05-6 Pentoxifylline

  • Product Name: Pentoxifylline Tag: Trental,Pentoxifylline,Pentox, Pentoxil and Flexital 1. Basic Information: Product Name Pentoxifylline Synonym Trental,3,7-Dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione CAS 6493-05-6 MF C13H18N4O3 MW 278.31...
  • Min. Order: 1
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  • China Shenzhen SiMeiQuan Biotechnology Co., Ltd. [Manufacturer]
  • Tel: 86-755-50755978
  • Address: #2 New District Road, Minzhi Street, Longhua New District, Shenzhen, China Shenzhen,GuangdongChina
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6493-05-6 1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
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6493-05-6 1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-

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6493-05-6 Pentoxifylline

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6493-05-6 PENTOXIFYLLINE

  • India JAI RADHE SALES []
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. ,India
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6493-05-6 PENTOXIFYLLINE

  • Germany BIOTREND Chemikalien GmbH [Manufacturer]
  • Tel: ++49 (0)2 21 9 49 83 20
  • Fax: ++49 (0)2 21 9 49 83 25
  • Address: BIOTREND Chemikalien GmbH
    Eupener Str. 157
    D - 50933 Cologne
    Germany ,Germany
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6493-05-6 PENTOXIFYLLINE

  • Germany Cfm Oskar Tropitzsch [Manufacturer]
  • Tel: +49-9231-9619-0
  • Fax: +49-9231-9619-60
  • Address: Cfm Oskar Tropitzsch
    Waldershofer Str. 49-51
    95615 Marktredwitz
    Germany ,Germany
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6493-05-6 Pentoxifylline

  • United States CBSCHEM LIMITED []
  • Fax: (888) 557-9843
  • Address: 621 South 48th Street, Suite 115,Tempe, AZ 85281 ,United States
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References of 3,7-dimethyl-1-(5-oxohexyl)purine-2,6-dione
Title: Pentoxifylline
CAS Registry Number: 6493-05-6
CAS Name: 3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione
Synonyms: 1-(5-oxohexyl)theobromine; 1-(5-oxohexyl)-3,7-dimethylxanthine; 3,7-dimethyl-1-(5-oxohexyl)-1H,3H-purin-2,6-dione; oxpentifylline; vazofirin
Manufacturers' Codes: BL-191
Trademarks: Azupentat (Azupharma); Durapental (Durachemie); Rentylin (Rentschler); Torental (Aventis); Trental (Aventis)
Molecular Formula: C13H18N4O3
Molecular Weight: 278.31
Percent Composition: C 56.10%, H 6.52%, N 20.13%, O 17.25%
Literature References: Methylxanthine derivative that improves blood flow by decreasing blood viscosity. Identity as a metabolite of pentifylline, q.v.: Mohler et al., Arch. Pharm. 299, 448 (1966); Mohler et al., Arzneim.-Forsch. 16, 1524 (1966). Prepn: NL 6511581; Mohler et al., DE 1235320; eidem, US 3422107 (1966, 1967, 1969 all to Chem. Werke Albert). Series of articles on chemistry, pharmacology and clinical trials: Arzneim.-Forsch. 21, 1159-1177 (1971). Toxicity data: K. Popendiker et al., ibid. 1160. Review of hemorheologic properties and use in cerebrovascular disease: R. Müller, F. Lehrach, Curr. Med. Res. Opin. 7, 253-263 (1981); of pharmacology and therapeutic uses: A. Ward, S. P. Clissold, Drugs 34, 50-97 (1987); C. P. Samlaska, E. A. Winfield, J. Am. Acad. Dermatol. 30, 603-621 (1994).
Properties: Bitter tasting, colorless needles from methanol, mp 105°. uv max: 273, 208 nm (E1%1cm 365, 935). Soly in water: 77 mg/ml at 25°, 191 mg/ml at 37°; in benzene: 11 g/100 ml. LD50 orally in mice: 1385 mg/kg (Popendiker).
Melting point: mp 105°
Absorption maximum: uv max: 273, 208 nm (E1%1cm 365, 935)
Toxicity data: LD50 orally in mice: 1385 mg/kg (Popendiker)
Therap-Cat: Hemorheologic agent.
Keywords: Hemorheologic Agent.