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CAS No 80-08-0 , 4-(4-aminophenyl)sulfonylaniline

  • Name: 4-(4-aminophenyl)sulfonylaniline
  • Synonyms: Sulfadione; Diaphenylsulfon; 80-08-0;4-(4-aminophenyl)sulfonylaniline; Sulfona; 4,4'-Diaminodiphenyl sulfone; Avlosulfone;Diaphenylsulfone; Diphenasone;
  • CAS Registry Number:
  • Transport: UN 3249
  • Melting Point: 173-178 ºC
  • Flash Point: 263.2 ºC
  • Boiling Point: 511.7 ºC at 760 mmHg
  • Density: 1.361 g/cm3
  • Water Solubility: <0.1 G/100 ML AT 20 ºC
  • Safety Statements: R22
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 263.2 ºC
  • EINECS: 201-248-4
  • Molecular Weight: 248.30088
  • InchiKey: MQJKPEGWNLWLTK-UHFFFAOYSA-N
  • InChI: InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,
    16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
  • Risk Statements: S22
  • Molecular Formula: C12H12N2O2S
  • Molecular Structure:CAS No:80-08-0 4-(4-aminophenyl)sulfonylaniline
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80-08-0 Bis(4-aminophenyl) sulfone

  • Bis(4-aminophenyl) sulfone
  • Hong kong Frapp's Pharma (Hongkong) Co.,Ltd [Manufacturer]
  • Tel: +852 8130 0917
  • Fax: +852 8130 0927
  • Address: Room 801,Mongkok Harbour Centre,638 Shanghai Street,Mongkok,Kowloon,Hongkang518001 MongkokHONG KONG Mongkok,Hong kong
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80-08-0 4-Aminophenyl sulfone

  • United States HBCChem, Inc. [Manufacturers]
  • Tel: +1-510-219-6317
  • Fax: +1-510-675-0318
  • Address: Union City,CaliforniaUnited States
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80-08-0 4-Aminophenyl sulfone

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80-08-0 4-Aminophenyl sulfone

  • 4-Aminophenyl sulfone
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,China
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80-08-0 4,4'-Diaminodiphenyl sulfone, 98%

  • 4,4'-Diaminodiphenyl sulfone, 98%
  • Belgium Alkemi [Manufacturer]
  • Tel: +32 9 340 49 49
  • Fax: +32 9 340 49 47
  • Address: Poststraat, 82 B-9160 Lokeren Belgium ,Belgium
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80-08-0 4,4' - Diaminodiphenyl sulfone

  • 4,4' - Diaminodiphenyl sulfone, 99.0%Min
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,China
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80-08-0 4-Aminophenyl sulfone

  • 4-Aminophenyl sulfone
  • China Shanghai Synnad Chemical Co., Ltd. [Importer/Exporter]
  • Tel: 86 21 5109 7911
  • Fax: 86 21 5109 7955
  • Address: B-5 Ecust Science Park, No. 18, Lane 1305, Hua Jing Road, Shanghai 200231 China Shanghai,ShanghaiChina
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80-08-0 Acedapsone

  • Acedapsone, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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80-08-0 Diaminodiphenyl sulfone

  • Diaminodiphenyl sulfone
  • China Shenzhen sailing chemical Co.,Ltd [Manufacturer]
  • Tel: 86-755-26415005
  • Fax: 86-755-26412646
  • Address: 1-403 Bei tou hao yuan Nanxing Road Nanshan District Shenzhen, Guangdong 518051 shenzhenCHINA shenzhen,China
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80-08-0 8499.12-100 DAPSONE

  • Germany Campro Scientific GmbH [Manufacturer]
  • Tel: +49.(0)30.629.01.89.0 (Germany)/ +31.(0)318.529.437 (Netherlands)
  • Fax: +49.(0)30.629.01.89.89
    +31.(0)318.542.181
  • Address: Campro Scientific GmbH
    Postfach 36 20 65
    D-10972 Berlin
    Germany
    Tel. +49.(0)30.629.01.89.0
    Fax +49.(0)30.629.01.89.89
    info@campro.eu ,Germany
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References of 4-(4-aminophenyl)sulfonylaniline
Title: Dapsone
CAS Registry Number: 80-08-0
CAS Name: 4,4¢-Sulfonylbisbenzeneamine
Synonyms: 4,4¢-sulfonyldianiline; bis(4-aminophenyl)sulfone; 4,4¢-diaminodiphenyl sulfone; DDS; diaphenylsulfone; DADPS
Manufacturers' Codes: 1358F
Trademarks: Avlosulfon (Wyeth-Ayerst); Croysulfone; Diphenasone; Disulone (Specia); Dumitone; Eporal; Novophone; Sulfona-Mae; Sulphadione; Udolac (Mallinckrodt)
Molecular Formula: C12H12N2O2S
Molecular Weight: 248.30
Percent Composition: C 58.05%, H 4.87%, N 11.28%, O 12.89%, S 12.91%
Literature References: Prepn: FR 829926 (1938 to I. G. Farbenind.), C.A. 33, 1761 (1939); Buckles, J. Chem. Educ. 31, 36 (1954); Ferry et al., Org. Synth. coll. vol. III, 239 (1955). Antibacterial action and metabolism: J. Francis, A. Spinks, Br. J. Pharmacol. 5, 565 (1950). Mechanism of toxic action: Wu, DuBois, Arch. Int. Pharmacodyn. Ther. 183, 36 (1970). Comprehensive description: C. E. Orzech et al., Anal. Profiles Drug Subs. 5, 87-114 (1976). Review of pharmacology and therapeutic use: J. Uetrecht, Clin. Dermatol. 7, 111-120 (1989). Clinical trial with chlorproguanil, q.v., in drug-resistant malaria: T. Mutabingwa et al., Lancet 358, 1218 (2001).
Properties: Crystals from 95% ethanol. mp 175-176° (also a higher melting form, mp 180.5°). pKb 13.0. Soluble in alcohol, methanol, acetone, dil hydrochloric acid. Practically insol in water.
Melting point: mp 175-176° (also a higher melting form, mp 180.5°)
pKa: pKb 13.0
Use: Hardening agent in the curing of epoxy resins.
Therap-Cat: Antibacterial (leprostatic); in treatment of dermatitis herpetiformis.
Therap-Cat-Vet: Antibacterial; coccidostat.
Keywords: Antibacterial (Synthetic); Sulfones; Antibacterial (Leprostatic); Dermatitis Herpetiformis Suppressant.